Not exact matches
Though wholesalers like McKesson have limited control over what happens to the
drugs they drop off
at the pharmacy door, they have a legal obligation to maintain an
effective system that will help prevent diversion; they are required to detect and report «suspicious orders» — those of unusual size, frequency or deviating from a customer's normal patterns — to the DEA.
Drugs that were
effective at warding off infections decades ago are now less potent because the bacteria they were designed to kill have developed defence mechanisms.
Drugs that were
effective at warding off infections decades
These
drugs were used primarily to treat cancer but they were also reasonably
effective in producing medical abortion,
at least up to eight weeks gestation.
Treatment is seven times more cost -
effective than domestic law enforcement, ten times more
effective than interdiction, and 23 times more
effective than attacking
drugs at their source.
Are
drug laws any more
effective at protecting us than gun laws?
Private companies taking full responsibility for their products is far more
effective at promoting food safety than any government inspection program and the War on
Drugs has done much to ruin what little liberty we have left.
A 2005 study in the American Journal of Clinical Nutrition found that consuming almonds as part of a heart - healthy diet can be just as
effective at lowering LDL «bad» cholesterol levels as first generation statin
drugs.
Given the variety of strains and ways to take in the
drug, patients could find marijuana more
effective for their health conditions
at one dispensary rather than another.
In doing so, it is reiterating its support for a «war on
drugs» mindset and a punitive
drugs policy which all the evidence shows is not
effective at reducing
drug use.
In his words, «The wide acceptance of NYSC Scheme both
at the national and international levels is borne out by the noteworthy contribution of Corps members to such exercises as the electoral process, the
effective nationwide campaign against HIV / AIDs, Road accidents,
Drug Abuse, Human Trafficking, Corruption, Illiteracy and the implementation of various aspects of the SDGs programme.
As a result, Soviet pharmaceutical companies churned out billions of units of questionable
drugs that were only partially
effective at normal dosages, weakening bacteria but not killing them outright — an environment perfect for spurring antibiotic resistance.
«If
drugs are proved not to be
effective or to have some bad effects, [there may be] pressure not to publish these findings
at all,» Anderson says.
When Gupta's team added salinomycin to cultured human breast - cancer cells, it was about 100 times as
effective at killing the cancer stem cells as popular anti-cancer
drug, paclitaxel.
At the end of the 3 years, the
drug was shown to be
effective and the same patients were offered the choice of taking a statin or not.
If proved correct,
drugs that modify the immune system may be
effective at treating this and other psychiatric conditions that may be associated with mutated microglia, says Capecchi.
Mitchell Cohen, a microbiologist
at the Centers for Disease Control and Prevention, in Atlanta, says that although he finds the EGS approach to
drug resistance «very clever,» in the long run, it may be no more
effective than another new antibiotic.
The authors — Martin Llewelyn, a professor of infectious diseases
at Brighton and Sussex Medical School, and nine British colleagues — point to recent studies that have shown shorter courses of certain
drug classes such as quinolones are as
effective as the longer courses that have been recommended in the past.
University of Melbourne Professor, Leann Tilley, an Australian Research Council Laureate Fellow
at the Bio21 Institute, tested the new
drug in red blood cells infected with parasites and found that it was as
effective at killing the artemisinin resistant parasites as it was for the sensitive parasites.
If dozens of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed
at last of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably
effective drug for relieving or preventing a variety of neurological disorders, including Parkinson's disease, mild cognitive impairment (MCI), Tourette's and schizophrenia.
Other studies suggest that nicotine may be as
effective at enhancing attention as methylphenidate (Ritalin) and the wakefulness - promoting
drug modafinil (Provigil).
As a result, infectious disease experts currently try to find a balance between making sure
drugs are
effective at knocking out harmful bacteria while keeping the treatment duration to the bare minimum required to stamp out an infection.
Since cows are so good
at making broadly neutralizing antibodies, it also might be possible to turn the cow's handiwork into
drugs for HIV treatment, if bovine antibodies are
effective at stopping the virus in other animals, he says.
Until now, EGFR inhibitors have only been
effective at treating the 10 to 15 percent of non-small cell lung cancers that have a variant of EGFR, but the two -
drug combo could potentially work for all non-small cell lung cancers, explained Dr. John Minna, Director of the Hamon Center for Therapeutic Oncology Research and Professor of Internal Medicine and Pharmacology.
Christian Confavreux, a neurologist
at Pierre Wertheimer Neurological Hospital in Lyon, France, and a member of that team, says that pregnancy is more
effective at keeping MS in check than
drugs commonly used to treat it.
Previous research
at York showed that regulating cannabis use could result in more
effective strategies aimed
at helping
drug users to access the right support and guidance.
The antibiotic, first identified by Nosopharm, is unique and promising on two fronts: its unconventional source and its distinct way of killing bacteria, both of which suggest the compound may be
effective at treating
drug - resistant or hard - to - treat bacterial infections.
For example, a study just out in The Lancet, funded by the U.S. Food and
Drug Administration and focused on Medicare patients, found that the high - dose vaccine was 22 percent more
effective at preventing flu - related hospital admissions.
«New study is an advance toward preventing a «post-antibiotic era»: Biologists identify
drug combinations that may be highly
effective at reducing growth of deadly bacteria.»
A statin
drug commonly used to lower cholesterol is not
effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine
at Temple University Hospital in Philadelphia, PA..
«These findings are important for cancer treatments, as currently there are no
drug therapies for enchondromas and there are no universally
effective chemotherapies for chondrosarcomas,» said senior author Benjamin Alman, M.D., chair of the Orthopaedic Surgery Department
at Duke University Medical Center.
«These
drugs are highly
effective and well - tolerated by patients
at all stages of liver disease.»
But some of these
drugs are only
effective after several months, and their use is «based on very weak evidence,» Niklas Långström, a psychiatric epidemiologist
at KI, said
at the press conference.
«One criticism of the PARP
drugs is they are not active in patients who have developed resistance to other therapies, but we found veliparib appears to be
effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author of the study and professor and vice chair of clinical research
at the University of Texas MD Anderson Cancer Center, Houston.
An existing anti-stroke
drug is an
effective treatment for middle - ear infections, showing the ability to suppress mucus overproduction, improve bacterial clearance and reduce hearing loss, according to researchers
at Georgia State University and the University of Rochester.
Over her time
at FDA, Woodcock has moved up, first by running the review group for biologics, then becoming the deputy director of biologics, then head of the Office of Therapeutics, and finally being appointed head of the Center for
Drug Evaluation and Research (CDER), a division of FDA committed to ensuring that «all prescription and over-the-counter
drugs are safe and
effective.»
An affordable hepatitis C combination treatment including the new
drug candidate ravidasvir has been shown to be safe and
effective, with extremely high cure rates for patients, including hard - to - treat cases, according to interim results from the Phase II / III STORM - C - 1 trial presented by the non-profit research and development organisation
Drugs for Neglected Diseases initiative (DNDi)
at the International Liver Conference in Paris.
Realizing they might have a potentially
effective drug on their hands, Bogyo and his colleagues brought in Sonnenburg, whose lab is adept
at using mouse models of C. difficile infection.
When all the evidence is weighed together, Prozac, Paxil, and other such popular pills seem to be
at best weakly
effective against depression — an argument Kirsch presses in his new book, The Emperor's New
Drugs.
A new insight into immune cells by scientists
at The University of Manchester could lead to more
effective drug treatments.
Achim Harder, head of anthelmintic research
at Bayer, the German company that makes praziquantel, says it is not clear why the
drug is less
effective in Senegal.
However, this security system is so
effective at protecting the brain that it prevents many life - saving
drugs — all but some small molecules — from being able to treat cancer and other diseases of the brain.
MDR - TB Multi-drug-resistant tuberculosis, defined as strains that resist
at least two of the most
effective anti-tubercular
drugs.
A
drug used to treat men with late - stage prostate cancer proved
effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute
at Oregon Health & Science University (OHSU).
Detection of dementia
at the earliest stages has become a worldwide priority, because
drug treatments, prevention strategies and other interventions will likely be more
effective very early in the disease process, before extensive brain damage has occurred.
Using virtual tissue technology, researchers
at Indiana University have identified a potential new
drug target in the fight against polycystic kidney disease, an illness with no
effective FDA - approved treatment that affects 200,000 people per year in the United States.
By performing experiments in petri dishes and with mice, they found that panobinostat, a
drug designed to change the way cells regulate genes, may be
effective at inhibiting DIPG growth and extending survival rates.
Although
effective new
drugs based on such research may be decades away, near - term payoffs could include ways of identifying teens
at risk of developing schizophrenia early on, or tools that help physicians better manage their patients» medications, added Steve McCarroll, director of genetics research
at Broad.
With
drug - resistant strains running rampant, a few hospitals have limited use of certain antibiotics for months
at a time — on the assumption that hardier
drug - sensitive strains would outcompete the resistant bugs and allow the
drugs to be
effective once again.
However, this security system is so
effective at protecting the brain that it prevents many life - saving
drugs from reaching the cancer.