Sentences with phrase «effective drug candidates»

The findings of this study suggest a new way to find more effective drug candidates with optimal kinetic and thermodynamic properties.

Not exact matches

By accelerating promising drug candidates through the drug discovery and development pipeline and spearheading innovative public - private partnerships, we increase the chance of finding an effective treatment, and a cure, for Alzheimer's disease.

Researchers from the UK and Denmark have developed a new method to predict the physical stability of drug candidates, which could help with the development of new and more effective medicines for patients.

Neural machine translation has been a latecomer to the game of deep learning, a method of making predictions about everything from effective marketing pitches to potential drug candidates.

An affordable hepatitis C combination treatment including the new drug candidate ravidasvir has been shown to be safe and effective, with extremely high cure rates for patients, including hard - to - treat cases, according to interim results from the Phase II / III STORM - C - 1 trial presented by the non-profit research and development organisation Drugs for Neglected Diseases initiative (DNDi) at the International Liver Conference in Paris.

A new paper published in the journal Science Translational Medicine describes the discovery and biological profiling of an exciting new anti-malarial clinical drug candidate, MMV390048, effective against resistant strains of the malaria parasite, and across the entire parasite lifecycle, with the potential to cure and protect in a single dose.

The data obtained from this study provide a basis for more rapid, cost - effective clinical trials to evaluate new influenza drugs or to determine the efficacy of candidate vaccines for both seasonal and pandemic influenza.

Triple - negative cancers are so called because they do not express receptors for the hormones estrogen and progesterone, nor for HER2 (human epidermal growth factor 2), and hence patients with these cancers are not candidates for treatment with modern hormonal therapies or the highly effective HER2 - targeted drug Herceptin (trastuzumab).

Draper's human organ system should be able to identify effective drugs and ineffective ones early in the drug discovery process, allowing developers to refocus resources on the strong candidates earlier and end unproductive research earlier, minimizing costs, Borenstein said.

Snowdon, Inc. has discovered prospective drug candidates that address the urgent need for safe and effective medicines in three major therapeutic areas — cancer, pain, and infectious diseases.

As potential lead drug candidates, we generated a large number of derivatives of the curry spice curcumin, which is effective in AD transgenic mice [8, 9].

The early intervention strategy is most frequently used for drug testing in AD because drug candidates assayed in AD transgenic mice at the stage when pathology is already present are generally less effective [27 — 30].

«It also was effective against known drug - resistant strains of the HIV virus, making it a very promising candidate for further development into a new HIV drug.»

Their hope is that drug candidates that get as far as animal testing and clinical trials will then be more likely to be safe and effective.

«The goal of the deCODE collaboration was to generate a final optimized compound with the required properties of an effective SMA drug, called a «Clinical Candidate».

Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost - effective decision making in exploratory development and increase phase II success.

«Although more than 30 drug candidates derived from fragment - based methods have entered the clinic, Wyss's work shows this approach can be effective even on a particularly difficult target,» comments Daniel Erlanson, the symposium organizer and cofounder of Carmot Therapeutics, a biotech company that focuses on FBLD.

Drugs (oral, injectable or transdermal) Opioids — these drugs are related to morphine and there are several safe and effective candidates in this cateDrugs (oral, injectable or transdermal) Opioids — these drugs are related to morphine and there are several safe and effective candidates in this catedrugs are related to morphine and there are several safe and effective candidates in this category.

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