Sentences with phrase «effective drug combinations»
And City of Hope is a leader in personalized medicine, including clinical trials here that are finding new and more effective drug combinations to kill lung cancer cells.
https://www.cityofhope.org/ Not exact matches
But a nonprofit is making its own hepatitis C combination medication that it says is just as effective as those created by for - profit drug giants.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
This drug combination may be a more effective therapy for portal hypertension and warrants further clinical evaluation, the researchers wrote.
The research team currently is working to identify new biomarkers that will allow them to develop a better understanding of how drug resistance develops, and how to best design effective combinations of medications that may improve patient responses.
A key to the study is an understanding that using two, three or more antibiotics in combination does not necessarily make the drugs more effective in combating bacteria — in fact, in many cases, their effectiveness is actually reduced when drugs are used together — so the combinations must be chosen carefully and systematically.
Dr Sian Clarke from the London School of Hygiene & Tropical Medicine, also a principal investigator in the research, said: «This study shows that rapid diagnostic tests can improve the use of artemisinin - based combination therapies — the most effective treatment for malaria — in drug shops, but it's not without its challenges.
«I doubt a single drug will ever work in this cancer, so it is a matter of finding which drugs in combination are going to be most effective,» says Dr. Smallridge.
(Five of the three - drug combinations were less effective than they expected, and the other 13 groupings performed as they predicted.)
«New study is an advance toward preventing a «post-antibiotic era»: Biologists identify drug combinations that may be highly effective at reducing growth of deadly bacteria.»
The new paper also provides the first detailed explanation of how the scientists created a mathematical formula that can help predict which combinations of drugs will be most effective.
Among the three - drug combinations, the researchers found two that were noticeably more effective than they had expected.
Drug classes found to meet «Level A» criteria in the study (established as effective for treating acute migraine) included triptans, dihydroergotamine (DHE), many NSAIDS (nonsteroidal anti-inflammatory drugs), butorphanol nasal spray, and the combination medications sumatriptan / naproxen and acetaminophen / aspirin / caffeine.
Studies show that PD - 1 inhibitors are effective for a larger proportion of melanoma patients than ipilimumab alone — and, in combination with that drug, they achieve a two - year survival rate of 80 percent.
An affordable hepatitis C combination treatment including the new drug candidate ravidasvir has been shown to be safe and effective, with extremely high cure rates for patients, including hard - to - treat cases, according to interim results from the Phase II / III STORM - C - 1 trial presented by the non-profit research and development organisation Drugs for Neglected Diseases initiative (DNDi) at the International Liver Conference in Paris.
Patient - derived xenographs involve the implantation of tumor tissue into an immunodeficient mouse which becomes an avatar to help identify which drug or drug combinations are most likely to be effective for an individual cancer patient.
Additional experiments using a combination of maraviroc and a drug that blocks the VEGF protein suggest that the treatment duo could be an effective way to prevent metastatic disease in human breast cancer patients, according to the researchers.
A subsidy program intended to drive down the cost of lifesaving malaria drugs called artemisinin - based combination therapies — now considered the most effective treatment against the parasitic disease — was unveiled today in Norway.
The other study showed how using a combination of drugs at increased potency could prove an effective therapy against glioblastoma by inhibiting the PI3K and MAPK cellular pathways.
Many Africans get their malaria drugs in the private sector, from local pharmacies or village shops, where the latest and most effective generation of drugs, the so - called artemisinin - based combination therapies (ACTs), are often hard to find and expensive.
We've also found that when these drugs are used in combinations, they don't reach high enough concentrations within the brain tumor to be effective.
The shorter, safer and more effective antifungal drug regimen treats cryptococcal meningitis with a one - week combination antifungal regimen of amphotericin B and flucytosine for the initial induction phase of treatment.
If this combination of drugs proves effective, we may be able to improve outcomes for this deadly disease.
When that happens, patients have to switch to a new drug combination that can be less effective than the previous treatment.
A new study questions conventional wisdom on antibiotics — that a course should be taken to completion and that drug combinations can be more effective
«Drug combination may be highly effective in recurrent ovarian cancer.»
Clinical trials at other institutions have also shown that fixed - dose combination is nearly five times more effective at controlling high blood pressure than other drug therapies.
«It was found that drugs normally used to treat HIV / AIDS were also effective at inhibiting Ebola, alone, but more so in combination with interferon beta,» noted Dr. Branch, who is also an Associate Professor, Medicine and Laboratory Medicine and Pathobiology, University of Toronto.
The drugs were effective when used alone or in combination with other classes of antifungals.
«Our research adds weight to the idea that effective antifungal drugs can target even those mitochondrial proteins that are highly conserved in humans and fungi, and that this could be a way to make a broad spectrum antifungal combination therapy that would be less susceptible to resistance,» says Benjamin Vincent, a former graduate student in Whitehead Member Susan Lindquist's lab who is now a scientist at Yumanity Therapeutics.
We are very excited at the prospect that this drug combination may be much more effective in prolonging patients» lives.»
«Since doxorubicin is one of the cheapest drugs that is effective against many types of cancer but rarely used in colon cancer, the combination therapy could be highly effective in combating colon cancer while drastically lowering risk of cardiotoxic side effects.»
Research from the University of Southampton has shown a drug, used in combination with chemotherapy to treat advanced colorectal cancer, is not effective in some settings, and indeed may result in more rapid cancer progression.
Not only could the new process ease the manufacture of existing protein therapeutics — and thus drop their price — but it could also speed the search for new so - called glycoprotein drugs, because researchers could easily attach different sugars to screen for the most effective combination.
In an animal model of AML, treatment with a combination of FLT3 - and SYK - inhibiting drugs was significantly more effective than treatment with either drug alone.
A team of Massachusetts General Hospital (MGH) investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma.
Some cancer drugs inhibit secreted growth factors but have been only partially effective at blocking angiogenesis (SN: 6/7/03, p. 358: Available to subscribers at Cancer Advance: Treatment combinations stall colorectal cancer).
This study is intended to evaluate whether the combinations of these drugs are effective in the treatment of 2 different types of metastatic melanomas depending on whether there is a mutation of the BRAF gene.
Or if used in a vaccine, they may be most effective in combination with other drugs: a few patients in the small clinical trials whose cancer relapsed after the trials responded to treatment with a checkpoint inhibitor.
Erinna says that based on current results, the researchers now believe that a drug targeting BFL - 1 could be highly effective for treatment of melanoma, particularly if used in combination with the currently available MCL -1-targeting molecule.
A combination of two diabetes drugs was more effective in treating 10 -17-year-olds with recent - onset type 2 diabetes than one, according to researchers at Washington University in St. Louis who participated in a multicenter clinical trial funded by the National Institutes of Health (NIH).
2013 — Our scientists unravel complex chains of events that lead to skin cancer becoming resistant to drugs that target BRAF, and are the first to show that a new combination of drugs is more effective at slowing cancer's growth.
Because SLC6A14 is essential for tumour growth yet dispensable for normal development and tissue maintenance, small molecules that block amino acid import through this transporter could be effective and selective anti-cancer agents, particularly as components of rational drug combinations.
For antigen induced tolerance to be effective, combination therapies may also include an anti-inflammatory drug to create the appropriate environment for sustained suppression of autoimmunity.
December 6, 2011 Drug combination highly effective for newly diagnosed myeloma patients, study finds A three - drug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly diagnosed patients, according to a multi-center study led by Andrzej Jakubowiak, MD, PhD, professor of medicine and director of the multiple myeloma program at the University of Chicago Medical CenDrug combination highly effective for newly diagnosed myeloma patients, study finds A three - drug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly diagnosed patients, according to a multi-center study led by Andrzej Jakubowiak, MD, PhD, professor of medicine and director of the multiple myeloma program at the University of Chicago Medical Cendrug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly diagnosed patients, according to a multi-center study led by Andrzej Jakubowiak, MD, PhD, professor of medicine and director of the multiple myeloma program at the University of Chicago Medical Center.
From a single sample taken from a patient's tumor, SEngine scientists can discover which drugs or combinations of drugs are most effective in killing or disabling that individual's cancer.
Treatment (which may involve therapy, drugs, or a combination of the two) is very effective.
«Our thinking is that the combination is safe, free of any side - effects and may prove to be as effective as drugs used for management of diabetes.»
The combination of grape extract and physical activity offers more protection than physical activity alone 06.03.2018 Grape Seed Extract during menopause: fewer hot flushes, more muscle and better sleep 12.08.2015 Poo smells less with Grape Seed Extract supplement 08.08.2015 Slimming supplement containing ECGC, resveratrol and Grape Seed Extract shown to work in human study 12.01.2014 Grape Seed Extract speeds up damaged muscle tissue recovery 15.09.2013 Grape Seed Extract keeps big eaters» weight down 11.12.2012 Grape Seed Extract helps prevent swollen legs 06.08.2012 Grape Seed Extract inhibits «genetically inevitable» prostate cancer 14.07.2012 Resveratrol and Grape Seed Extract protect against skin cancer 02.03.2012 Red grape juice is a smart drug 18.11.2011 Gallic acid is the anti-cancer agent in Grape Seed Extract 12.11.2011 Grape Seed Extract protects against prostate cancer 11.11.2011 Grape Seed Extract protects against skin cancer 29.10.2011 Anti-cancer supplements like GSE need plant - based proteins to be effective 21.09.2011 Arginine with grape extract enhances condition condition 25.06.2010 Grape Seed Extract inhibits aromatase & glucocorticoid receptor 05.08.2009
A study on rats found that a combination of ginger and turmeric was more effective than a standard anti-inflammatory drug at treating the impairment of kidney functions (5).