Instead migraine sufferers may be given other, less
effective drugs such as opioid narcotics.
Not exact matches
So many companies have developed
such increasingly
effective medicines,
such as those that treat more hep C strains with far shorter treatment regimens, that Gilead — a pioneer in the field with Sovaldi and Harvoni — is projecting $ 3.5 billion to $ 4 billion in U.S. sales from these kinds of
drugs in 2018, a dramatic drop from nearly $ 13 billion in 2015.
InvivoSciences will continue to contribute to the improvement of human health by establishing a new paradigm for discovering
drugs that focus on diseases with limited treatment options
such as cardiac fibrosis, scleroderma, and lupus in a time -
effective manner while remaining safe and cost
effective.»
While
drug treatments are potentially dangerous and not highly
effective for symptoms ascribed to colic or GER, one partial exception may be the older type of acid - reducing
drugs such as Zantac, still prescribed today.
«As
such, the conventions recognize that, to be truly
effective, a State's response to offences by
drug abusers must address both the offences and the abuse of
drugs (the underlying cause).»
The Youth Rise also stated that it was also excited about Saraki's call for the review of all
drug related laws, stating that
such a review would lead to a more
effective framework to tackle the
drug menace across Nigeria.
In his words, «The wide acceptance of NYSC Scheme both at the national and international levels is borne out by the noteworthy contribution of Corps members to
such exercises as the electoral process, the
effective nationwide campaign against HIV / AIDs, Road accidents,
Drug Abuse, Human Trafficking, Corruption, Illiteracy and the implementation of various aspects of the SDGs programme.
With new research —
such as Cutrer's theory about the nature of aura — more possibilities for tailoring
effective drugs have emerged.
Dr. McCabe said nanoparticles are a leading - edge technology also being studied for delivery of
drugs for other conditions,
such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and side effects of those medications and to make them more
effective.
«Furthermore, risk of ischaemic heart disease can be reduced substantially by other lifestyle changes, as well as by
drugs such as statins shown to be
effective in primary prevention.»
The authors — Martin Llewelyn, a professor of infectious diseases at Brighton and Sussex Medical School, and nine British colleagues — point to recent studies that have shown shorter courses of certain
drug classes
such as quinolones are as
effective as the longer courses that have been recommended in the past.
Total knee and hip replacements are highly
effective operations for patients with severe pain in these joints, and opioids are the main
drugs used for acute pain management after
such surgeries.
«If we could load these virus shells with a different cargo, say a
drug, and target it to a particular place in the body,
such as a tumor, it could then deliver the
drug to just that specific location, making the
drug more
effective, or reducing side effects,» Lawrence said.
«Using this technology, the study is the first to discover the critical role of astroglial cells in Down syndrome as well as identify a promising pathway for exploring how a
drug such as minocycline may offer an
effective way to help treat it.»
African Americans are less supportive than either whites or Hispanics of allowing access to experimental
drug treatments before
such treatments have been shown to be safe and
effective.
Previous research has suggested that anti-inflammatory
drugs such as aspirin used in conjunction with antipsychotic treatments may be more
effective than just the antipsychotics themselves.
Preventative treatment of malaria is a useful strategy to protect young children in Africa, but it is unclear which
drug and dosing strategy is most
effective, especially with the rise of resistance to a class of
drug known as antifolates,
such as sulfadoxine - pyrimethamine (SP) and trimethoprim - sulfamethoxozole (TS).
Checkpoint inhibitors already produce unprecedented rates of long - term remission for a handful of hard - to - treat cancers, but their potential is even greater: Because
such drugs modify the body's response to cancer, rather than the cancer itself, they could theoretically be
effective against almost any kind of malignancy.
When all the evidence is weighed together, Prozac, Paxil, and other
such popular pills seem to be at best weakly
effective against depression — an argument Kirsch presses in his new book, The Emperor's New
Drugs.
For example, the study defined cases of pancreatic cancer that are driven by a gene called BRAF, for which there are FDA - approved
drugs, and showed that
such drugs were selectively
effective against BRAF - mutated pancreatic cancer cells.
«For example, we found that highly aggressive ovarian cancer cells are glutamine - dependent, and in our laboratory studies, we showed that depriving
such cells of external sources of glutamine — as some experimental
drugs do — was an
effective way to kill late - stage cells.
Given the progressive nature of MS, the debilitating nature of fatigue, and the lack of
effective fatigue
drug treatments that work for the majority,
such findings are encouraging and important.
Although
effective new
drugs based on
such research may be decades away, near - term payoffs could include ways of identifying teens at risk of developing schizophrenia early on, or tools that help physicians better manage their patients» medications, added Steve McCarroll, director of genetics research at Broad.
«Given the potential for future lethal pandemics,
effective drugs are needed for the treatment of severe influenza,
such as that caused by H5N1 viruses,» says senior study author Yumiko Imai of Akita University.
Thanks to the organism's creation, synthetic biologists are learning more about customizing cells,
such as for development of highly
effective drugs and energy alternatives to fossil fuels.
A system just published in Chemistry of Materials by a group of researchers from Oregon and the United Kingdom offers an even more
effective way to deliver
such drugs and may be able to greatly improve this approach, scientists say.
Such drugs would be much more
effective at killing cancer cells while leaving healthy cells unhurt, which significantly reduces side effects for patients.»
Stimulants and other
drugs such as modafinil are often very
effective in helping narcoleptics fend off sleepiness during the day.
Parish says these positive results suggest the
drugs might be
effective against other autoimmune diseases
such as multiple sclerosis.
Dr Natalie Carter, head of research liaison and evaluation at Arthritis Research UK, said: «While this
drug is known to be
effective for some forms of inflammatory arthritis,
such as rheumatoid arthritis, this study does not back up its use for hand osteoarthritis.
Discouraged by recent findings that antiviral
drugs such as zidovudine (AZT), ddI and ddC are less
effective than had been hoped, many people with HIV, and their doctors, are now confused about how and when to use them.
The findings open up new avenues of research into exactly how the brain controls eating, and suggest that
drugs designed to activate or inhibit neurons in the DRN could be
effective in treating obesity and preventing its related disorders,
such as diabetes and hypertension.
Researchers at University of Florida Health have discovered the mechanics of how dopamine transports into and out of brain cells, a finding that could someday lead to more
effective treatment of
drug addictions and neurological disorders
such as Parkinson's disease.
While this limits the clinical implications of using a 24p3 inhibitor as a sole treatment for leukemia, adding it to a cancer
drug such as Gleevec might prove
effective, he says.
«The approach may be extended to additional complex disorders and diseases for which we don't understand the underlying biology but do have
drugs that may have some beneficial actions,
such as depression, anxiety, schizophrenia and others in need of more
effective therapies.
In general, the
drugs are
effective for about 70 percent of those who take it, although Viagra does have side effects
such as flushing, headache, heartburn, and, rarely, visual disturbances.
I have been especially interested in testing
drugs that can inhibit MMPs in cancer models and in understanding why
such drugs have not been
effective in human cancer patients.
«If we could catch Alzheimer's disease before this occurred,
such an amyloid - removing
drug might stop it in its tracks, but once tau tangles and neurodegeneration have set in this approach would be unlikely to be
effective.
Compounds found in the milk of Australia's Tasmanian devil were found
effective at killing disease - causing pathogens
such as the
drug - resistant bacteria MRSA.
These research collaborations have the power to answer questions critical to improving cancer outcomes,
such as how tumors develop
drug resistance, and what treatments are most
effective against particular genomic traits.
The researchers say the findings provide an explanation for recent evidence showing that anti-angiogenesis
drugs such as Avastin can be much more
effective when combined with chemotherapy.
Such approaches are becoming less
effective due to the emergence of pesticide - resistant mosquito populations and
drug - resistant strains of the parasite.
A better handle on the basic biology of intranasal oxytocin,
such as how it enters the brain and which receptors it hits, might enable researchers to develop more
effective drugs, Young adds.
Compared to
such blunt, non-specific
drugs, our immune system is a complex, highly
effective system, responsible for protecting us against most diseases and keeping us healthy for the duration of our lives.
Because viruses have evolved
such effective methods for finding their target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting therapeutic vehicles that can deliver
drugs to specific cells or tissues or selectively target and destroy tumors.
A
drug that blocks the serotonin 1b receptors may be
effective in reducing OCD symptoms; however, no
such chemical is currently available, Dulawa said.
Through
such evolutionary processes, a
drug that targets telomerase could seem
effective at first, only to be defeated by the cancer cell line if it can (for instance) more effectively break the
drug down, or prevent the
drug from entering its cells, or put out the biological equivalents of the «chaff» and flares that are used by fighter jets to ward off the targeting systems of hostile missiles.
«Injecting
drugs such as collagenase, verapamil — a calcium channel blocker — and interferon - alpha - 2b is an option,» says Dr. Goldstein, «though only interferon has been shown to be
effective.»
Prescription narcotic painkillers —
drugs such as Oxycontin, Vicodin and Percocet — are not as
effective as NSAIDs for inflammatory pain, he explained.
While
effective, these
drugs have the potential to cause undesirable side effects
such as weight gain, memory impairment, and sedation.