Intrigued by the ability of certain polymers to mop up DNA and RNA for gene transfer, Sullenger and colleagues tested the idea that these chemical compounds might also be
effective targeting such nucleic acids as they arise in cell death.
Not exact matches
«Flash activism,» the label I prefer for online protest forms
such as online petition, can be
effective at influencing
targets in specific circumstances.
Perhaps the most
effective measure that British Government could use to help achieve its
target of cutting teenage pregnancy rates is to introduce a rule giving prohibiting confidential abortions for minors,
such that parents would have to be informed or, better still, would have to consent to their youngsters having an abortion.
Social media sites
such as Facebook and other online platforms provide an
effective way sending your
targeted advertising messages to people within the locality of your business.
This article discusses implementation research in the home visiting field, how
such research can be used to strengthen programs and improve
targeted outcomes, and the conditions and supports necessary for
effective implementation.
In support of this model, multiple studies have shown the association between infant negative reactivity and later psychosocial outcomes
such as problem behaviour and self - regulation to be moderated by parental behaviour, so that highly reactive children fare better than others when they experience optimal parenting but worse than others when they experience negative parenting.41 - 46 Further support is found in studies indicating that interventions
targeting parental attitudes and / or behaviours are particularly
effective for children with a history of negative reactive temperament.47, 49
If your child does have depression with impulsive and / or aggressive behaviors, certain treatments may be more
effective in decreasing these behaviors,
such as coping skills training, anger management and certain medications
targeted toward impulse control.
In addition, Affected State Entities may receive credit towards meeting the
Target for installing on - site renewable generation if the host site for
such renewable generation has deployed all cost -
effective energy efficiency improvements consistent with the goals of this Executive Order.
Dr. McCabe said nanoparticles are a leading - edge technology also being studied for delivery of drugs for other conditions,
such as cancer, heart disease, and bacterial infections, in order to
target specific cells to reduce toxicity and side effects of those medications and to make them more
effective.
Therefore, common treatments
such as endocrine therapy and molecular
targeting of the HER - 2 receptor are not
effective for this breast cancer subtype.
«If we could load these virus shells with a different cargo, say a drug, and
target it to a particular place in the body,
such as a tumor, it could then deliver the drug to just that specific location, making the drug more
effective, or reducing side effects,» Lawrence said.
In
such situations there is no single
target (like Washington or Moscow) for nukes, rendering them less
effective either as offensive weapons or deterents.
The results from the study could be used to help public health officials to plan a more
effective response to future pandemics,
such as rolling out vaccines at a much earlier time and
targeting specific types of vaccines at different age groups.
Of course, there might be other explanations
such as improved awareness among the public of security issues and identity theft and the like as well as more
effective and so protective software and security systems on putative
targets of cybercrime including as email phishing attacks on bank account, for example.
«Having an accurate overview of how different regions of countries are connected by human movement aids
effective disease control planning and helps
target resources,
such as treated bed nets or community health workers, in the right places.
«Memory training needs to
target specific difficulties to be
effective, suggests study: A recently published Baycrest study suggests that training programs can help, but only if they are tailored towards an individual's specific memory difficulty,
such as trouble remembering faces, voices or recent events.»
When given to diseased mice, the engineered T cells
targeted and killed B cells that express antibodies
targeting desmoglein 3, hinting that
such a strategy may be an
effective way to treat antibody - driven autoimmune diseases.
«Methods
such as the stable isotope assignment approach in this paper are extremely important because they give us a starting point for making these kinds of assignments, and pave the way for more
effective and
targeted management of Golden Eagle populations.»
«PHB is a druggable
target (
targeted by Rocaglamide) and as
such, it is hoped that our work paves the way towards an
effective treatment able to prevent the neurological complications associated with EV71 infections.»
In
such cases, the patient will be treated with a cocktail of chemotherapy instead of a more appropriately
targeted treatment, which could be more
effective and gentler on the patient.
TNBC is deadly because, unlike other types of breast cancers
such as estrogen receptor (ER) positive or HER2 amplified breast tumours which have
effective targeted therapy, TNBC tumours do not respond to
targeted therapy.
--
Effective on January 1, 2033, and once every 3 years thereafter, the Secretary shall determine, after notice and opportunity for comment, whether further energy efficiency building code improvements for residential or commercial buildings, respectively, are life cycle cost - justified and technically feasible, and shall establish updated national building code energy efficiency
targets that meet
such criteria.
Particular cancers,
such as treatment - resistant breast cancers, have a unique dependence on transcription, meaning
targeting CDK7 may be particularly
effective.
«The knowledge of which HLA molecules are lost will be critical to develop
such effective therapies and choose the right antigens to
target.»
Because viruses have evolved
such effective methods for finding their
target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting therapeutic vehicles that can deliver drugs to specific cells or tissues or selectively
target and destroy tumors.
However, viruses, while
effective, introduce other problems to the body,
such as toxicity, immune and inflammatory responses, and gene control and
targeting issues.
Through
such evolutionary processes, a drug that
targets telomerase could seem
effective at first, only to be defeated by the cancer cell line if it can (for instance) more effectively break the drug down, or prevent the drug from entering its cells, or put out the biological equivalents of the «chaff» and flares that are used by fighter jets to ward off the
targeting systems of hostile missiles.
The chronic leukemias have very
effective treatments in the form of biologic therapies (
such as Gleevec for CML), which are designed to stimulate the body's immune system to
target cancer cells.
A one
such study indicates that HIIT is very
effective in
targeting abdominal body fat during intermittent fasting.
Some experts even suggest that the plank is way more
effective for your abs than any other other exercise that directly
target your abs,
such as crunches or sit ups.
This herb is particularly
effective for
targeting such headaches.
Some of these treatments
such as Gerson Therapy work to strengthen and balance the immune system and take some time to be
effective while other treatments,
such as High Dose Vitamin C intravenous therapy,
target cancer cells safely and work right away to decrease tumor load, allowing time for the nutritional program to work.
Programs promoting spot reduction,
such as those
targeting spare tires with crunches, are a distortion of the most
effective ways to achieve weight loss, according to the American Council on Exercise.
Failure is ONLY
effective, when you overload the positive stress intensity factor on the
target muscle to
such a degree and in the minimal possible duration, that another perfect style rep (POSITIVE FAILURE is incapable of being performed.
The FEBS Journal reports that curcumin is particularly
effective in
targeting hormone - dependent forms of the disease
such as breast cancer.
Effective coaching programs respond to particular needs suggested by data, allowing improvement efforts to
target issues
such as closing achievement gaps and advocating for equity.
As
such, you have to find the one that
targets the Big Data you need to make your eLearning
effective.
Specific strategies for
targeted purposes,
such as
effective early intervention programs designed to identify at - risk students;
There is evidence that computer - based tutoring can yield results similar to one - on - one tutoring in certain subjects,
such as science, technology, engineering, and math (STEM) fields, 27 or when certain principles of the cognitive science of learning —
such as self - explanation — are embedded in the program or software.28 While these programs can not replace the need for human interaction and relationships, they may be
effective for some students and allow for greater
targeting of resources toward students who most need traditional one - on - one tutoring.
Facebook ads were particularly
effective because I could
target fans of similarly geeky books by authors
such as Daniel Suarez and Charles Stross.
There are some criteria on which you're not allowed to do price discrimination -
such as race / gender / ethnicity / etc; but it's both allowed and
effective to charge different customer
target groups different prices for essentially the same thing.
After the
effective date of the ban, dogs in the municipality that are identified as
targeted breeds are usually subject to being killed by animal control, though in some cases,
such dogs may be saved if relocation is an option.
On the other hand, the
targeted sterilization approach at the heart of programs
such as Albuquerque's has proven
effective at reducing the population of unowned free - roaming cats.
«We strongly urge the government to set
such a
target, using cost -
effective energy efficiency gains to help meet its goal,» Mr. Mandil emphasised.
Integrated assessment models (IAMs) take underlying socioeconomic factors,
such as population and economic growth, as well as a climate
target —
such as limiting warming to 1.5 C — and estimate what changes could happen to energy production, use, and emissions in different regions of the world to reach the
targets in the most cost -
effective way.
The request shall specify the maximum proportion of annual combined
targets (not more than two fifths) that can be met through demonstrated total annual electricity savings, and the period for which
such proportion shall be
effective.
Although economic analyses can provide policy - makers with valuable information
such as which technologies will achieve ethically determined goals at lowest cost, thereby providing criteria for making remedies cost -
effective, there are serious ethical problems with cost - benefit analyses used prescriptively to set emissions reductions
targets.
And, if home insulation is a cost -
effective method of reducing emissions, which householders are neglecting for reasons
such as credit constraints, the scheme could allow the
target to be reached at lower social cost.
[132] Policies implemented by governments have included [133][134][135] national and regional
targets to reduce emissions, promoting energy efficiency, and support for renewable energy
such as Solar energy as an
effective use of renewable energy because solar uses energy from the sun and does not release pollutants into the air.
While
such videos cost considerably more to create, in the long run, they will be far more
effective at conveying expertise and authority to your
target audience.