Sentences with phrase «effective therapeutic target»
Abnormal BMIPP identifies specific myocardial injury which could be an effective therapeutic target for preventing sudden cardiac death.»
https://www.sciencedaily.com/ Not exact matches
Broadening the therapeutic targets is essential to develop an effective treatment.
This pathway may serve as a target for the development of an effective therapeutic.
This webinar will examine how, by targeting proteins responsible for the crosstalk between epigenetics and metabolism, we may be able to develop new and effective therapeutic options for cancer treatment.
«This makes it important to identify new therapeutic targets for the development of effective treatments,» the investigators conclude.
«We have identified a novel therapeutic target for the treatment of severe influenza that is effective under conditions where known antiviral drugs fail to protect from death.»
«Ultimately, figuring out how to target PC may help researchers develop new, more effective therapeutic strategies to improve upon current lung cancer treatments, which are limited and harmful.»
«This breakthrough could lead to more effective therapies for women with this very common subtype of breast cancer and be the therapeutic target that the drug companies have been waiting for.»
Most importantly for individuals with FOP, the study identifies HIF - 1α as a therapeutic target — knowledge that will likely contribute to the development of more effective treatments for FOP and related common disorders of heterotopic ossification.
Whilst a handful of these genes including DOT1L, BCL2 and MEN1 are already established therapeutic targets, most of them are novel and open up many new possibilities for developing effective treatments against the disease.
New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.
C. Develop ways to overcome cancer's resistance to therapy Identify therapeutic targets to overcome drug resistance through studies that determine the mechanisms that lead cancer cells to become resistant to previously effective treatments.
«This project could lead to new therapeutic targets and more effective and safer drugs for the disease.»
Penn Medicine's Hematologic Malignancies Translational Center of Excellence seeks to redefine the diagnostic and therapeutic approach to blood cancers in order to provide more effective targeted therapies.
Martin Carroll, MD and Edward Stadtmauer, MD are leading efforts at this TCE to redefine the diagnostic and therapeutic approaches to blood cancers — including leukemia, lymphoma and myeloma — and provide more effective targeted therapies.
The Hematologic Malignancies Translational Center of Excellence (TCE) is a multidisciplinary center that seeks to redefine the diagnostic and therapeutic approaches to blood cancers, including leukemia, lymphoma and myeloma, and provide more effective targeted therapies.
The ultimate goal of this work is to contribute to the design of effective therapeutic approaches that target dysregulated ER functions for patients with leukemia and other malignancies.
Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost - effective decision making in exploratory development and increase phase II success.
These targets are then fed into an active drug discovery program to develop effective therapeutic strategies for the improved treatment of cancer patients.
Because viruses have evolved such effective methods for finding their target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting therapeutic vehicles that can deliver drugs to specific cells or tissues or selectively target and destroy tumors.
This research was effectuated to create a theranostic bioconjugate with an optimal effective therapeutic index, achieved by biomarker - specific targeting.
Exposure therapy is widely appreciated as one of the most effective therapeutic treatments for anxiety spectrum disorders; however, it is often underutilized due to problems that present themselves during treatment, such as client unwillingness or hesitancy, or a lack of understanding on the professional's part regarding targeted applications.