Sentences with phrase «effective vaccine which»

Not exact matches

The new oral rabies vaccine should prove more effective than prior versions, which may lead to a drop in rabies in our raccoon populations.

The researchers are currently planning a follow - up study which will test whether a flu vaccine is more effective for the elderly when combined with brief use of Losmapimod.

Exactly which organization or nation might fund the mass production of these vaccines, assuming they prove effective, also remains an open question.

Dr. David Cavanagh, of the University of Edinburgh's School of Biological Sciences, who led the study, said: «There is a desperate need for an effective vaccine, which can be made easily in large quantities, to protect against this devastating disease.

Researchers have new insights into how protective antibodies attack dengue viruses, which could lead to more effective dengue fever vaccines and drug therapies.

With HIV, progress has been slow, but we have a glimmer of hope now from the so - called RV144 trial in Thailand, in which an experimental HIV vaccine turned out to be about 30 percent effective.

Professor Ajit Lalvani from the National Heart and Lung Institute at Imperial College London, who led the study, said: «New strains of flu are continuously emerging, some of which are deadly, and so the Holy Grail is to create a universal vaccine that would be effective against all strains of flu.»

If there can be a low - cost vaccine which is effective in rendering the parasite harmless, then millions of lives can be saved and this will also benefit the economy by millions of dollars each year, says Prof Preiser.

He adds that the findings, which are published in the online 26 September issue of Nature Medicine, may be applicable to other infectious diseases such as tuberculosis, for which no highly effective vaccine exists.

Learning more about the new strains could help public health officials to determine which drugs might be effective and to design new vaccines for the next flu season, which will likely include strains that are now circulating.

To develop an effective vaccine, it is imperative to identify a suitable antigen structure of the virus which will create an effective immune response in humans.

One of the vaccines, which is based on a recombinant vesicular stomatitis virus expressing the glycoprotein of the Zaire strain of the Ebola virus (VSV - ZEBOV), was recently shown to be extremely effective with 100 per cent efficacy against the lethal Ebola virus disease in WHO - funded studies carried out in Guinea and Sierra Leone.

A group of leading scientists from across Europe have launched a three - year project aimed at developing an oral vaccine against Clostridium difficile, an infection that kills around 4,000 people a year (almost four - times more than MRSA) and for which there is currently no effective treatments.

Current vaccines, which require experts to pick the flu strains that they believe are going to circulate in a given year, are typically 40 to 70 percent effective in the U.S., though in some years protection is as low as 20 percent.

Recent studies have shown that locally made Chinese vaccines are less effective than imported versions, which cost five to 10 times as much.

The researchers are now looking at how ICOS signals can be altered to diminish autoimmune disorders and augmented for more effective vaccine development, and are beginning research on how ICOS signaling may benefit Chimeric Antigen Receptor - T cell (CAR - T) therapies, which involves engineering of patient's own immune cells to recognize and attack their cancers.

Gandhi reports that his team's estimates, which are not yet complete, find a basically negligible demand of 10 million treatments for a minimally effective vaccine.

Perhaps, the researchers hypothesized, the minute changes make the vaccine less effective, which could explain the reappearance of the disease.

Candidate vaccines against Ebola or malaria — one of which recently received an important stamp of approval in Europe — should definitely be used if they are safe and effective, he says, but they could lead to more virulent pathogens.

«Taken together, these two studies suggest that the new scalable vaccine formulation is likely to prove as effective as the original formulation — which would make it the first protective TB vaccine in humans since BCG, which was introduced almost a century ago,» said Professor Ajit Lalvani, Director of the Tuberculosis Research Centre, National Heart and Lung Institute, Imperial College London and a member of the DAR - 901 development team.

Maria A. Croyle and colleagues note that in the current Ebola outbreak, which is expected to involve thousands more infections and deaths before it's over, an effective vaccine could help turn the tide.

The standard smallpox vaccine, a virus called vaccinia, is amazingly effective, which explains how the disease was eradicated in the late 1970s.

Because the immune system mounts an inadequate protective response against HIV, an HIV vaccine most likely will not be as effective as proven vaccines used to control or end global outbreaks, such as yellow fever and polio vaccines, which are nearly 100 percent effective.

This kind of research — figuring out which of the many HIV strains are affecting local people and how they are transmitted — is essential for designing an effective vaccine.

Or it might be necessary to reformulate the vaccine to make it effective against dengue serotype 2, which would also require redoing the clinical trials.

The DNA vaccine for Zika virus is more immunogenic and effective than other vaccines because it can create memory responses, which inactivated vaccines with killed viruses fail to produce, Higgs said.

Dr Gambhir said the team looked at whether a randomized control trial (RCT)-- where all people in the population have the same chance of being selected; or a stepped - wedge cluster trial design — which would give vaccine to healthcare workers and eventually treat all of them — is most safe and effective in evaluating a vaccine.

«Our findings support PfSEA - 1 as a potential vaccine candidate, and we are confident that by partnering with our colleagues at the National Institutes of Health and other researchers focused on vaccines to prevent the parasites from entering red blood cells, we can approach the parasite from all angles, which could help us develop a truly effective vaccine to prevent this infectious disease that kills millions of children every year.»

His research could help scientists develop more effective vaccines and treatments for allergies and autoimmune diseases, which occur when our bodies make antibodies wrong, and they end up attacking the body itself.

We aim to develop a globally - effective HIV vaccine which, in combination with other proven prevention strategies, would enable us not only to protect our Warfighters from HIV, but would be critical in the control of the global pandemic.

PHILADELPHIA --(April 19, 2018)-- The Wistar Institute and partners at the Perelman School of Medicine at the University of Pennsylvania, Inovio Pharmaceuticals, and GeneOne Life Science were recognized among the Top 10 Clinical Research Achievement Awards by the Clinical Research Forum for their ground - breaking phase 1 DNA - based Zika vaccine research — the first trial of a Zika vaccine in humans, which proved safe and effective.

The vaccine, which has proven effective in trials on rodents and monkeys, works by mimicking the unique structure of the heroin molecule and its key metabolite, 6 - acetylmorphine.

«The two greatest challenges remaining in HIV / AIDS research are finding a cure and developing a safe and effective preventive vaccine,» said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, which is leading the vaccine trial.

Next steps are correlates research, which is underway, and regional clinical studies, with the goal of developing a globally - effective vaccine.»

For example, the UK government's program for tackling HIV and AIDS in the developing world, which was published shortly after the Bangkok meeting, makes the unqualified comment that the enterprise «will accelerate research and development of an effective vaccine.»

Prof Ajit Lalvani from the National Heart and Lung Institute, who led the study, said: «New strains of flu are continuously emerging, some of which are deadly, and so the Holy Grail is to create a universal vaccine that would be effective against all strains of flu.»

We exploit these findings to design a chemically synthesized peptide corresponding to RH5Nt, which could contribute to a cost - effective malaria vaccine.

I currently work at the National Institute of Allergy and Infectious Diseases, which has opened my eyes to the need for more safe and effective vaccines for an array of diseases.

Another research goal is a safe and more broadly effective vaccine, which remains one of the most difficult challenges, according to Drs. Fauci and Eisinger.

She noted that the Canadian researchers estimated that the flu vaccine is 55 percent effective against influenza B viruses, which typically cause more infections late in the season.

THURSDAY, Sept. 29, 2016 (HealthDay News)-- The vaccine against human papillomavirus (HPV) infection, which doctors believe causes most cases of cervical cancer, appears even more effective than believed, a new study finds.

This is a new strain that's just been discovered, so there's no vaccine for it — which is usually the most effective way to control dissemination.

The next problem is that the age at which vaccine can be effective is different for each individual puppy.

Adjuvants cause the vaccine to be more effective at stimulating an immune response, which is the way that vaccines provide protection from disease.

Core vaccinations are for diseases that are common, easily transmitted, and severe, and in which the vaccines have been shown to be safe and effective.

Scientists have been trying to develop a human leptospirosis vaccine for decades — one that's safe and effective and which governments will license around the world.

While no vaccine is 100 % effective, vaccinating your dog against Lyme disease in areas in which it is prevalent is absolutely essential,» said Dr. Laura Weis of Doylestown Veterinary Hospital & Holiday House Pet Resort.

Thyro - Cat administers radioactive iodine I - 131 therapy (which is also used for overactive thyroids in humans) for feline hyperthyroidism in diagnosed cats as easily and quickly as a vaccine, as it is injected just under the skin; and is entirely safe and effective for your cat.

Vaccines against the H3N8 influenza virus — which has existed in this country for more than a decade — are available, but there are differences in the genetic sequences of the two strains that suggest that these vaccines would be poorly effective, or ineffective in protecting dogs against the H3N2 virus infecting dogs in the MidwestVaccines against the H3N8 influenza virus — which has existed in this country for more than a decade — are available, but there are differences in the genetic sequences of the two strains that suggest that these vaccines would be poorly effective, or ineffective in protecting dogs against the H3N2 virus infecting dogs in the Midwestvaccines would be poorly effective, or ineffective in protecting dogs against the H3N2 virus infecting dogs in the Midwest.»

Which vaccine and what has been studied in lab trials determines how often a vaccine needs to be boostered or how often it needs to be repeated in an adult animal to be effective.