Sentences with phrase «effectiveness of drugs used»

Regardless of whether Landrigan's legal team was simply using the drug shortage as stalling tactic, their legal maneuvering brings to the fore a contentious dispute over the science (or some would say lack thereof) behind lethal injection executions in the U.S.. For more than two decades, it has been argued that the FDA should be required to certify the safety and effectiveness of drugs used to carry out executions (as it does for drugs used to euthanize animals).

Not exact matches

On November 8, the US House of Representatives held a hearing on the effectiveness of a 1999 law known as the Kingpin Act, which is used to sanction individuals suspected of involvement in the drug trade.

The Home Office cites falling drug use in the UK as evidence its policies are working, but critics point out illegal drug use is falling internationally and is probably not connected to the effectiveness of government policy.

When a class of drugs called triptans became available in the early 1990s, Healy used them, but over time their effectiveness dimmed.

The agency has ongoing research examining the effectiveness of drugs such as methadone, buprenorphine, and naltrexone that are used to wean people off of stronger opioids, as well as research developing alternatives such as vaccines and transcranial magnetic stimulation to treat opioid addictions.

To test the safety and effectiveness of microdosing, the researchers delivered a common drug ophthalmologists use to dilate the pupil and examine the back of the eye.

Published in the journal Molecular Cancer Therapeutics, the study also found that use of a second inhibitor might improve the effectiveness of these drugs by possibly preventing resistance, and it recommends that clinical trials should be designed to include a second inhibitor.

In a new Essay publishing 28 December in the open access journal PLOS Biology, Kristofer Wollein Waldetoft and Sam P. Brown of Georgia Institute of Technology propose that development of alternative therapies for mild infections could help slow the development and spread of antibiotic resistance, thereby preserving the drugs» effectiveness for use in severe infections.

Tina Hernandez - Boussard, Ph.D., of Stanford University, Stanford, Calif., and colleagues conducted a review and meta - analysis to evaluate the effectiveness of commonly used drug - free interventions for pain management after TKA.

In any given season, the effectiveness of the vaccine depends on how good a match there is between the viruses used in the drug's production and the strains that are actually circulating that year.

Many patients and physicians assume that the safety and effectiveness of newly approved drugs is well understood by the federal Food and Drug Administration (FDA)-- but a new study by researchers at Yale School of Medicine shows that the clinical trials used by the FDA to approve new drugs between 2005 and 2012 vary widely in their thoroughness.

«This is the first time the 3 - D culturing method has been used to predict the effectiveness of different drugs on tumors from individual patients,» said graduate student Alex Walsh, who has played a key role in developing the test.

Treatment using such antibodies is extremely expensive, however, and oncologists are keen to find a biomarker that can predict the effectiveness of these drugs for individual patients.

The drug, called AQ - 13, was able to clear the parasite responsible for the disease within a week, matching the effectiveness of the most widely used treatment regimen.

This, in turn, amplifies the effectiveness of fulvestrant, a drug commonly used in this subset of patients.

As reported in the journal Angewandte Chemie, this drug blocks key enzymes used in mycomembrane biosynthesis, significantly increasing the effectiveness of conventional antibiotics.

Ultimately, the goal is to use stem cells of an individual patient and create a personalized model of their reproductive system to test new drugs for safety and effectiveness.

Its effectiveness in several clinical trials led the U.S. Food and Drug Administration to approve preventive use of ARVs in 2012.

Introduction of 9 - 12 month courses of multidrug - resistant tuberculosis therapy will increase the effectiveness of treatment and reduce the total number of anti-tuberculosis drugs during the course of treatment and save funds that can be used to treat more patients.

Raydiance's technology has attracted the attention of the U.S. Food and Drug Administration (FDA), which in July 2007 signed the company to a two - year cooperative research and development agreement that has allowed the FDA's Center for Devices and Radiological Health (CDRH) to evaluate the use, safety and effectiveness of Raydiance's USP laser system in a number of areas, including the ablation of corneal tissues in refractive surgery and corneal repair; the administration of light therapy for treating cancer, cardiovascular disease and diabetes; and the removal of plaque on teeth without damaging the enamel.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices.

Although a small number of repurposed and new drugs have recently become available to treat drug - resistant TB (including bedaquiline, delamanid, and linezolid), the authors warn that without accurate diagnostic tests to deliver individually targeted treatments, clear prescription guidelines on appropriate use and improved control efforts to prevent transmission, optimal dosing and administration, and well - functioning health care systems, the effectiveness of the drugs could be rapidly lost.

The data were considered using meta - analysis, an approach long used in fields such as biomedicine to determine the effectiveness of a treatment based on studies with a variety of patient groups, providers and ways of administering the therapy or drugs.

The researchers examined the effects of a widely used African botanical supplement, called Sutherlandia, and found that it may disrupt the effectiveness of a common anti-tuberculosis drug.

The ultimate goal is to precisely understand the mechanisms of checkpoint blockade effectiveness and bring next generation, sustainable immunotherapies to even more patients, perhaps using by using epigenetic drugs in combination with checkpoint blockade to allow epigenetic reprogramming of exhausted T cells into durable and functional memory T cells.

Researchers have found a way to increase the effectiveness of a widely used cancer drug while decreasing the risk of heart - damaging side effects, according to a new study by researchers from The University of Texas Medical Branch at Galveston and Texas Tech University Health Sciences Center.

In laboratory tests using rodents, White and his colleagues found that while morphine lost its pain - relieving effectiveness three weeks after nerve injury, a combination therapy of morphine and carbamazepine — used to prevent epileptic seizures — could effectively reverse this loss of drug action.

Using a mathematical modeling approach, scientists have found that certain parameters of tumor growth in mice can predict the effectiveness of drugs that block formation of tumor - nourishing blood vessels.

The drug will be given to a larger group of people to confirm its effectiveness and compare it to commonly used stroke treatments.

Researchers from the University of Missouri School of Medicine have developed an imaging technique using a specific form of helium to measure the drug's effectiveness.

If bacterial resistance to those drugs is already high because of their use as animal - growth promoters, they could have limited effectiveness as infection fighters in people, he says.

Despite the long - recognized, time - dependent variation in the effectiveness of many commonly used drugs, there has been little use of chronotherapy in clinical practice.

Drug discontinuation rates are an indicator of effectiveness and may be used in health economic models to determine cost - effectiveness.

But before such a drug can be used, Gupta explained, scientists have a precise way to quantify the latent HIV reservoir, which would allow for the effectiveness of the drug to be measured.

To date, a screen of the collection of FDA - approved drugs in the Prestwick Library has identified a handful of potential candidates which have demonstrated effectiveness at lowering secretion of IL - 6, a component of SASP whose concentration tends to rise systemically with aging and here used as a preliminary marker of SASP as a phenotype.

Using a drug we know can target the garbage disposal system of the brain, we will test the effectiveness of this treatment in a model of AD.

She and her collaborators found that gut bacteria impact the effectiveness of indomethacin, an anti-inflammatory drug used to treat pain and arthritis.

The most profound effect of stem cells in the meantime could be to screen new drugs for safety and to gauge a medication's effectiveness on real human tissue without using patients as guinea pigs.

In addition to providing a simple and much less expensive means of making artemisinin, the most powerful anti-malaria drug in use today, synthetic biology can also help to extend the effectiveness of this drug...

Researchers from University College London and King's College London have examined the effectiveness of using drugs that are currently being trialled in cancer patients to treat autoimmune disease in mice.

Phase I Trials initial studies to determine the safety and pharmacologic actions of drugs in humans, and the side effects associated with increasing doses; in some cases can also be used to gain early evidence of effectiveness.

A study published in a recent issue of the journal Neuron revealed that fluorescent compounds used in brain scans prove might help researchers diagnose the disease, monitor treatment effectiveness, and test new drugs.

The DASH diet's effect for some people with gout was so strong that it nearly matched the effectiveness of drugs normally used to treat the painful condition, the study authors said.

Additionally, Vitalzym can increase the effectiveness of certain medications; another reason to consult with a doctor or pharmacist prior to using them if taking prescription drugs.

Using ella with hormonal contraceptives such as birth control pills could reduce the effectiveness of both drugs in preventing pregnancy.

[1] This article evaluates the effectiveness of curcumin in treating Rheumatoid Arthritis (RA) during different phases of the disease, using different routes of administration, and by comparing it to other pharmaceutical drugs.

Using ella with hormonal birth control such as birth control pills can reduce the effectiveness of both drugs to prevent pregnancy.

And «because the safety and effectiveness of ayahuasca has yet to be determined, it should only be used in the context of careful research studies, designed to protect the safety of patients, while generating data that could inform the overall balance of risks and benefits associated with this drug,» he said

They used two measurements to gauge a drug's effectiveness and tolerability: the percentage of patients who showed at least a 50 % improvement in their symptoms as measured by one of two scales, or who scored «much improved or very much improved» after eight weeks of treatment (or from 6 to 12 weeks if eight - week data wasn't available) and the percentage of patients who dropped out of the study before eight weeks for any reason.

Basically, Dr. Parikh explains, Dr. Cipriani and the other researchers were able to make comparisons among drugs that hadn't been studied head - to - head by using their effectiveness as compared to Prozac — the best studied of these drugs — as a kind of common currency.