Sentences with phrase «effectiveness of these drugs for»

Treatment using such antibodies is extremely expensive, however, and oncologists are keen to find a biomarker that can predict the effectiveness of these drugs for individual patients.

Phase II Trials clinical studies conducted to evaluate the effectiveness of the drug for a particular disease or signs or symptoms in patients with the disease or condition under study and to determine the common short - term side effects and risks.

Researchers hope that if the ongoing preliminary studies prove the safety and effectiveness of these drugs for certain treatments, the government will step in to fund larger trials.

Not exact matches

Sidenote: Chew is also one of the few biopharma execs I've ever spoken to who voluntarily brought up the Institute for Clinical and Economic Review (ICER), a tough drug pricing critic organization which insists on proven outcomes (and has consequently become a major biopharma gadfly), because the group actually validated the cost - effectiveness of Omada's tech.

The endorsement came despite lingering questions about safety and effectiveness, but also followed a high - stakes pressure campaign in which the manufacturer accused the Food and Drug Administration of gender bias, since several pills were already approved for men with sexual problems.

This generally supports the case that Living Goods offers high quality products, but because our experience on the site visit may have been non-representative and there are many other potential factors that may affect the effectiveness of drug treatments aside from following storage procedures for drugs properly, we consider it to be only weak evidence in support of the quality of Living Goods» drug treatments.

If they want their drugs to be provided in those wards and if they want it to be eligible for that forced savings dollars, they have to price it at a level of cost effectiveness that the Singaporean government likes.

Being one of the most thoroughly researched plants ever; it's been claimed to match the effectiveness of drugs including statins like liptor, corticosteroids, antidepressants, anti-inflammatories, and drugs for chemotherapy and diabetes.

A new report has questioned the effectiveness of random drug testing in schools, calling for further evidence on their probable impact.

To guide the spending of that money, the National Institute of Medicine made a priority list of situations for which data about outcomes are badly needed — for instance, comparing the effectiveness of various medical and behavioral interventions to prevent the elderly from falling (the complications of which are a leading cause of death), comparing assorted drugs and surgeries alone or in combination in the treatment of specific cancers, comparing the effectiveness of different implants and devices for treating hearing loss, and so forth.

With this kind of review process, if 20 studies of the effectiveness of a truly ineffective drug are conducted, and one of them shows a significant effect with a p - value of 0.05 because of chance alone, investigators for the other 19 studies not showing any effect would presumably not be inhibited from writing up and submitting reports of these for publication out of fear that they'll be denied publication because of their nonsignificant results.

The NAPOLI - 1 (NAnoliPOsomaL Irinotecan) Phase 3 study — a final confirmation of a drug's safety and effectiveness — was conducted among patients with metastatic pancreatic cancer who previously received gemcitibine, which has been the standard - of - care therapy for such patients.

«Researcher develops, proves effectiveness of new drug for spinal muscular atrophy.»

St. Jude Children's Research Hospital leads study showing that a drug withdrawn from the market in 2010 may enhance the effectiveness of bone marrow transplants for select pediatric leukemia patients

In a new Essay publishing 28 December in the open access journal PLOS Biology, Kristofer Wollein Waldetoft and Sam P. Brown of Georgia Institute of Technology propose that development of alternative therapies for mild infections could help slow the development and spread of antibiotic resistance, thereby preserving the drugs» effectiveness for use in severe infections.

«We urgently need new treatments for lung cancer patients, and this research suggests we can boost the effectiveness of an existing drug, rather than switch to another new expensive treatment.

Researchers from the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester, who led the study, warned that failure to take the drugs correctly, known as «non-adherence», reduced their effectiveness and may lead to a worsening of patients» disease.

For example, the results of one study, known as UPLIFT, one of four large - scale studies conducted in 2008, demonstrated the effectiveness and safety of a drug called Spirivain about 6,000 patients with respiratory disease.

Tina Hernandez - Boussard, Ph.D., of Stanford University, Stanford, Calif., and colleagues conducted a review and meta - analysis to evaluate the effectiveness of commonly used drug - free interventions for pain management after TKA.

On the scientific agenda are identifying molecular markers for resistance, which would simplify testing; accelerating the development of alternative drugs; and studying the effectiveness of mass screening and treatment to eliminate malaria in the areas where resistance occurs.

In the randomised study, all patients with social anxiety disorder were treated with the same dosage of escitalopram for nine weeks, but only one group was correctly informed about the drug and its effectiveness.

notes G. Caleb Alexander, MD, MS, associate professor of Epidemiology and Medicine and co-director of the Johns Hopkins Center for Drug Safety and Effectiveness.

That goal is part of the Tissue Chip for Drug Screening program, which is funded by the National Institutes of Health to improve ways of predicting drug safety and effectivenDrug Screening program, which is funded by the National Institutes of Health to improve ways of predicting drug safety and effectivendrug safety and effectiveness.

Kipnes is currently recruiting patients for a second safety trial as well as a larger Phase 2 trial of the drug's effectiveness.

The drug, called AQ - 13, was able to clear the parasite responsible for the disease within a week, matching the effectiveness of the most widely used treatment regimen.

«Just like working memory can hold about 7 items and a drug can be effective for certain amount of time, social influence seems to have a limited time window for effectiveness.»

Vitamin B6 has been shown to have a small effect on hangover in scientific studies, as have prostaglandin inhibitors, a class of drugs that includes aspirin and ibuprofen; for optimum effectiveness these should be taken while you are drinking, not the next morning, though they can also help the morning after.

Motion - sickness drugs, for instance, take longer to reach a level of effectiveness in women.

Regardless of whether Landrigan's legal team was simply using the drug shortage as stalling tactic, their legal maneuvering brings to the fore a contentious dispute over the science (or some would say lack thereof) behind lethal injection executions in the U.S.. For more than two decades, it has been argued that the FDA should be required to certify the safety and effectiveness of drugs used to carry out executions (as it does for drugs used to euthanize animalFor more than two decades, it has been argued that the FDA should be required to certify the safety and effectiveness of drugs used to carry out executions (as it does for drugs used to euthanize animalfor drugs used to euthanize animals).

The Institute for Clinical and Econonic Review (ICER), an influential non-profit that studies the cost effectiveness of new drugs, is holding a meeting to review Luxturna on Jan. 25.

«The data from these two Phase III trials conducted in Europe and in the U.S. support the effectiveness of this novel photo - protective drug, offering the patients in Europe — where the drug has been approved by the European Medicines Agency — the opportunity to perform their daily functions without the pain induced by sun exposure,» said Robert J. Desnick, PhD, MD, Principal Investigator of the U.S. Trials and Dean for Genetic and Genomic Medicine, Icahn School of Medicine.

A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer.

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment — to dramatically slow and control tumors on a long - term, sustained basis, not necessarily aiming for their complete elimination.

Given the effectiveness of the drug cocktail, Hütter would not have considered such a risky procedure for AIDS alone.

Offsetting any such savings, according to CSDD, are higher costs due to the increased complexity of clinical trials, a greater focus on chronic and degenerative diseases, and tests for insurers seeking comparative drug effectiveness data.

Ultimately, the goal is to use stem cells of an individual patient and create a personalized model of their reproductive system to test new drugs for safety and effectiveness.

Raydiance's technology has attracted the attention of the U.S. Food and Drug Administration (FDA), which in July 2007 signed the company to a two - year cooperative research and development agreement that has allowed the FDA's Center for Devices and Radiological Health (CDRH) to evaluate the use, safety and effectiveness of Raydiance's USP laser system in a number of areas, including the ablation of corneal tissues in refractive surgery and corneal repair; the administration of light therapy for treating cancer, cardiovascular disease and diabetes; and the removal of plaque on teeth without damaging the enamel.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices.

Drs. Rajkumar and Kantarjian say other reasons for the high cost of cancer drugs include legislation that prevents Medicare from being able to negotiate drug prices and a lack of value - based pricing, which ties the cost of a drug to its relative effectiveness compared to other drugs.

That finding helps explain the effectiveness of some formerly mysterious treatments for malaria: The drugs attack chloroplasts.

Their results, published in PLOS Neglected Tropical Diseases, provide details on the procedure for evaluating candidate anti-Ebola drugs and comparing the antiviral effectiveness of eight drugs from three different drug classes.

Before arriving at a potential treatment for humans, the researchers are planning to evaluate the effectiveness of new drugs to awaken similar virus reservoirs in monkeys and determine where the virus is hidden.

A trained robotic surgeon experienced in the treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they need to penetrate into the tumour efficiently in order to reach the cystoplasm of all the cancer cells that are being targeted without affecting the normal cells.

The mice were developed in Roussel's laboratory and are a powerful tool for testing the effectiveness of drugs against human tumors.

«Effectiveness of drug to improve natriuretic peptide levels for chronic heart failure.»

«New imaging technique shows effectiveness of cystic fibrosis drug: Hyperpolarized helium MRI could aid in development of improved therapies for lung diseases.»

As it turns out, a group of atoms essential to the drug molecule's effectiveness, and also toxicity, made for a good attachment point.

It will also provide diagnostic tools for disease identification and allow medical professionals to measure the effectiveness of drug treatment regimes in an easy laboratory manner.

Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal, offering scientists a tantalizing target for new anticancer drugs of greater effectiveness and lower toxicity.

Watkins» work with glia, for example, has indicated that long - term opioid therapy may have an effect similar to that of chronic inflammation, causing glial cells to release an excess of cytokines that actually reduce the drug's effectiveness in blocking pain.