Sentences with phrase «effector complex»
His thesis was entitled «Structural and biochemical studies of Argonaute reveal the slicing mechanism of RISC - RNAi effector complex.»
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As well as innovative tools for basic research, CRISPR - associated effector complexes will be instrumental for developing the next generation of antiviral prophylactics and therapeutics.
Over the past decade, we have used computational and molecular approaches to annotate mi / si / piRNAs, and to elucidate mechanisms of how they are made and how they are sorted into appropriate Argonaute effector complexes.
Not exact matches
The next insight was to assemble a synthetic transcription activation complex consisting of multiple distinct effector domains that work together synergistically, modeled after natural transcription activation processes.
Rho GTPases and the Downstream Effectors Actin - related Protein 2/3 (Arp2 / 3) Complex and Myosin II Induce Membrane Fusion at Self - contacts.
Murine models of inflammatory arthritis have also expanded our understanding of the role of complex, inter-connected complement activation pathways and effector mechanisms.
Huynh, T.N., Santini, E., and Klann, E. (2014) Requirment of mammaliant target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence.
To examine the functional role of Smad1 and Smad5 in GDF5 - induced neurite length, primary cultures were transfected by microporation with siRNAs targeting the co-Smad4 (required for nuclear translocation of Smad1 / 5 transcriptional complex [33]-RRB- or the Smad1 and Smad5 effectors proteins, which are known targets of miR - 181a (Table 2).