Sentences with phrase «effector molecules»
"Effector molecules" refer to specific molecules in the body that carry out and initiate specific biological activities or responses. These molecules are responsible for triggering or influencing different functions and processes in cells, tissues, organs, or systems of the body. They act as messengers, signaling or causing certain actions to occur, including muscle contraction, enzyme activity, immune response, or hormone release, among others. Full definition
In addition to IL - 22, ILC3s produce other effector molecules such as IL - 17 and GM - CSF.
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We are currently investigating the details of the signaling cascades involved in these phenomena, as well as attempting to identify cytoplasmic binding partners for NG2 which may serve as effector molecules for activation of downstream signaling events.
Activation of multiple signaling pathways may allow cells to finely tune expression of effector molecules as well as provide redundancy and resiliency.
However, combined inhibition of both ERK1 / 2 and AKT did not increase additional cell death, indicating that the radiation - induced cell death in B16F10 cells is possibly mediated by common downstream effector molecules of ERK1 / 2 and AKT.
Antibodies are key effector molecules in health and disease as they harbor the ability to recognize specific molecular structures and, consequently, elicit immune responses.
We have shown here another potential mechanism for how lethal toxin perturbs barrier function through the down - regulation of a key effector molecule, IL - 22, in mucosal barrier maintenance and wound repair.
IL - 22 is one of the most important effector molecules produced by ILC3s.
Recently, we showed that bortezomib treatment in mice bearing breast and kidney tumors provided host survival benefit by amplifying tumor cell caspase8 activation, CD8T cell effector molecules via increased NotchNFkB crosstalk and Fas ligandmediated lysis of tumor cells.
MAIT cells secrete IFN - γ, IL - 17 and / or other effector molecules according to the context of triggering.
Most well - characterized effector molecules in other insects are secreted into the hemolymph: in our study, 91.2 % of previously identified AMPs have bioinformatic evidence indicating presence of a signal peptide.
In order to assess whether previously uncharacterized but highly - induced genes represent novel immune effector molecules, we assessed which and how many of these genes encode proteins that possess properties common to known AMPs.
In addition to IL - 22, ILC3s also secrete other effector molecules, including the cytokine GM - CSF.
Yang Y, Lu Y, Espejo A, Wu J, Xu W, Liang S, Bedford MT (2010) TDRD3 is an effector molecule for arginine - methylated histone marks.