Sentences with phrase «effector phenotypes»

Not exact matches

The phenotype of NP cells generated ex vivo (Figure S8) closely resembles that of central memory CD4 + T cells found in vivo, which persist for years in secondary lymphoid organs and can differentiate into effector memory CD4 + T cells [45].

Binding of adenosine to the A2A receptor on immune cells blocks the activation and effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.

The adenosine A ₂ ₐ receptor is the main adenosine receptor expressed on immune cell subsets including T - cells, NK cells and dendritic cells and binding of adenosine to the A ₂ ₐ receptor on immune cells blocks the activation and effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.

Furthermore, CMV - specific CTL have a highly polarized membrane phenotype that is typical of effector memory cells (CD28 -LRB--), CD57 (+), CCR7 -LRB--)-RRB-.