Moreover, recent studies show that T. gondii can deliver
effector proteins into cells that it does not invade [33], [34], and that these proteins can manipulate host cells without active parasite replication [35].
Not exact matches
They systematically deleted genes for secreted
effector proteins — molecules that the parasite injects
into a host cell to modulate the immune system during infection — and injected the altered parasites
into mice with aggressive ovarian cancer.
Further insight
into the basic details of CRISPR - Cas structure, functions, and biology — and characterization of new Cas
effector proteins in particular — is crucial for optimizing and further expanding the diverse applications of CRISPR - Cas systems.
However, all in all, a lot of basic research still needs to be carried out to fully understand the disease process: XopH is only one of a total of more than 35
effector proteins that bacteria inject
into plants to colonise them.
In their earlier work, the Halle lab already proved that the bacteria introduce numerous harmful
proteins, so - called
effectors,
into plant cells via a specialised secretion system which works like a molecular syringe.
A patent application has been filed and testing is underway on the
protein — called HT - TALENs (short for HIV - targeted transcription activator - like
effector nucleases)-- which uses a newly developed gene - editing technique to rid the body's cells of the immunodeficiency virus before it has a chance to multiply and possibly develop
into AIDS.