Sentences with phrase «effectors when»

Perhaps readers can suggest an alternative to this general approach for determining the potential of effectors when challenged with real parasites, in wild genetic backgrounds and in the presence of humans.

Partial activation of the yeast pheromone response pathway by beta - adrenergic receptor agonists was achieved in cells coexpressing h beta - AR and a mammalian G protein (Gs) alpha subunit - demonstrating that these components can couple to each other and to downstream effectors when expressed in yeast.

Not exact matches

Effector T cells incite GvHD when they become overactive as the patient's immune system starts to rebuild itself from the donor stem cells.

This «friendly fire» goes unchecked due to the failing of another type of immune cell: called the T - reg, which controls T - effector cells, shutting them down when they are not needed.

Whereas acute CD8 + T cell effector responses are enhanced in DGKζ - deficient mice postinfection with intracellular pathogens, persistent memory formation is impaired, most dramatically when both DGKζ and DGKα, the other isoform of DGK that metabolizes DAG downstream of the TCR in T cells, are deleted (35, 36).

Here we show that HO - 1 inducers inhibit antigen - specific effector T cells when injected intradermally together with the T cell cognate antigens in mice.

When considering the anatomy of the mucosal immune system, sites can be defined as either inductive or effector sites.

Since their first work together in 2000, Collmer and Martin have sought to tease apart the interactions between effectors and plant defense proteins, to understand how and when the plant's immune system responds.

Whereas when an effector is detected inside the plant cell, the plant knows for sure it is being attacked and it activates ETI, a very strong immune response,» said co-author Greg Martin, the Boyce Schulze Downey Professor at BTI.