Sentences with phrase «effects at those doses»

They also found that vitamin D did not improve lung function or day - to - day asthma symptoms, and that it did not increase the risk of side effects at the doses that were tested.

There isn't any other toxicant that we know of that even comes close to arsenic in terms of the number of health effects at the doses we're seeing and the numbers of people worldwide who are potentially exposed.»

But even more damning from a pharmacological perspective, the team found the same effect at all doses of either herbicide or GM maize.

There is a potential for side effects at those doses.

Not exact matches

But researchers at the University of Aberdeen found that a treatment originally designed for fighting cancer and diabetes could melt away fatty arterial plaque with a single dosing and reverse the effects of atherosclerosis, which can lead to multiple heart problems.

They had never really before tried to limit the negative effects of low interest rates — asset - price bubbles — while at the same time as applying a heavy dose of monetary stimulus.

Animal studies of the chemical have found it has no health effects on reproduction or development at doses up to at least 100 mg per kg of body - weight per day.

While you can't blame tryptophan for your inability to keep your eyes open this afternoon, that doesn't mean the hefty dose you'll get from eating way too much turkey doesn't have any effect on your mood at all.

Many of these effects are found at very low, physiologically relevant doses.

High - quality protein dosed at 0.4 — 0.5 g / kg of LBM at both pre - and post-exercise is a simple, relatively fail - safe general guideline that reflects the current evidence showing a maximal acute anabolic effect of 20 — 40 g

Even if conditions in the children's homes are chaotic and stressful, Educare's directors believe, the large dose of responsive care they experience each day at the center will allow them to transcend the potential ill effects of that instability.

The lactation team at The Breastfeeding Center of Chicago utilizes multiple research sources that rank medications by their level of safety, lists appropriate doses for moms to take, and lists potential side effects for babies.

However, lessons were learned from these early programmes and in 2004, the Texas Fragile Families initiative reported an increase in child support orders / paternity establishment among its participants (with a «dose» effect — the longer the young father was involved in the programme, the more likely he was to establish paternity / pay child support); and employment rates up from 50 % at the start of the programme to almost 70 % at six months and 80 % at one year (Romo et al, 2004).

Unfortunately you failed to report the results of the most definitive research on BPA, which found no evidence of health effect at low doses, or the conclusion from the NTP review.

Of the studies that have been done, one or more studies show reproductive effects at very low doses, organ system toxicity, and developmental / reproductive toxicity!

Ultimately, Papsin says, his study is about dose: «The recommendations for parents is to use machines for as short a duration as possible, as reduced a volume as possible, and at the farthest distance from the baby as possible to get the desired effect,» he says.

Because there are no standard dosages based on a child's weight, stimulants are usually started at a low dosage and gradually increased to find a child's best dose, which «is the one that leads to optimal effects with minimal side effects.»

Chemicals having estrogenic activity (EA) reportedly cause many adverse health effects, especially at low doses in babies and children.

Since 2006, almost 90 million doses of HPV vaccines have been administered nationally, and the most common side effects are soreness or swelling at the site of the shot.

This would help tamp down antibiotic resistance, while allowing doctors to lower the dosage of antibiotics that are toxic at high doses and that produce nasty side effects such as deafness and kidney damage.

«We know about the dose - limiting side - effects of liposomes, but no one had looked at what happens to the liposome over time in the skin — how they get there and what happens to liposomes after injection,» says Dmitri Simberg, PhD, investigator at the CU Cancer Center and the paper's senior author.

«At higher doses, most drugs start having less specific effects.

«Although there was an overall dampening effect of alcohol on the prefrontal cortex, even at a low dose of alcohol we observed a significant positive relationship between dorsomedial and dorsolateral prefrontal cortex activity and alcohol - related aggression,» explains Denson.

Re-challenging as well as switching statins — While switching statins and reducing doses are commonplace, re-challenging patients with the same statin at the same dose is unusual because patients often feel uncomfortable retrying a statin that they perceive has caused intolerable effects.

But the small viruses that deliver therapeutic genes can have adverse side effects at high doses.

Researchers at the Veterans Health Administration conducted a systematic review of 67 published studies to determine the effectiveness of strategies to reduce or discontinue long - term opioid therapy prescribed for chronic pain and the effect of dose reduction or discontinuation on important patient outcomes.

At lower doses, it temporarily produces the same schizophrenia - like effects as PCP.

Subjects who received liraglutide started at a dose of 0.6 mg, which gradually was increased to 3 mg, to minimize side effects, such as nausea.

Just because a molecule appears to heighten attention in a small study on a couple dozen people doesn't mean it will have any effect if it's mixed into a drink and given to someone at random at an unknown dose.

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

A separate review by Ducharme and a different group of colleagues looked at 22 studies that tested varying the dose of steroids, and found that lower doses had less of an effect on height.

«Our preclinical data suggest that combining low doses of these inhibitors will enhance the clinical effects of both drugs as a potential treatment for patients with AML,» says the senior author, Feyruz V. Rassool, PhD, associate professor of radiation oncology at the University of Maryland School of Medicine (UM SOM) and a researcher at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).

Michael Oshinsky at Thomas Jefferson University in Philadelphia, Pennsylvania, and colleagues tested the effect of low doses of ethanol — about the equivalent of a single drink — on rats prone to migraines.

Anaesthesiologist David Waisel at Harvard University is concerned Phillips may not be rendered sufficiently unconscious by the injected midazolam before the high dose of hydromorphone — which can cause soft tissue in the throat to collapse — takes effect.

The toxic effects started very soon after PTCs were exposed to HEC, and further increased at higher doses.

The effect is most severe at lower doses, according to new research, including concentrations similar to what might be found in the environment.

The cumulative long - term effect of these pollutants may be more important than the dose at which 50 % of a population of water fleas or minnows dies, he says.

In this prospective birth cohort study, researchers looked at the effects of low - dose chemical exposure in 164 pregnant women.

New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that's used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline.

Ezio Bonifacio, Ph.D., of the DFG Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Germany and colleagues randomly assigned autoantibody - negative, genetically at - risk children to receive oral insulin at varying doses (n = 15) or placebo (n = 10) once daily for 3 to 18 months to assess whether oral insulin can induce a potentially protective immune response without causing adverse effects.

In this prospective birth cohort study, he and colleagues looked at the effects of low - dose chemical exposure in 164 pregnant women.

At low doses, few adverse effects were seen in the flies as they continued to feed normally and produce healthy offspring.

«Using a mouse model of tuberculosis, we have shown lower doses of bedaquiline together with verapamil have the same antibacterial effect as the higher toxic doses,» says Shashank Gupta, Ph.D., a research fellow at Johns Hopkins.

So far, Markiewicz and his colleagues have found that if the polyethylene absorbs a dose of 12 kilograys of X-rays, the discharge effect can be suppressed at temperatures below 30 °C for several months.

Most of the side effects were considered manageable, although 37 percent of patients required at least one dose reduction and 6 percent discontinued therapy.

We're emphasizing that we really need to look at the low - dose effects.

By that I mean you can take 10 estrogenic chemicals at doses that on their own don't have an effect, but if you add them together, you end up with problems.

«The advantage of being able to deliver methotrexate in this targeted way is to be able to gain the benefits from this key treatment of RA, while reducing the risk of adverse effects that are more frequent at high doses,» concluded Dr Macor.

A dose - response effect was found in women randomized to weight loss counseling in that women who lost at least 5 % body weight experienced an approximate 22 % decrease in insulin, 38 % decrease in leptin, and 55 % decrease in CRP, compared to significantly less biomarker improvement in women randomized to weight loss who lost less than 5 % body weight.

Linda Birnbaum: The $ 30 million program that we have on bisphenol A is looking at what can bisphenol A do, especially developmental exposures: At what doses do these effects occur and how serious are theat what can bisphenol A do, especially developmental exposures: At what doses do these effects occur and how serious are theAt what doses do these effects occur and how serious are they?