Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the
following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the
effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the
effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the
effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of
diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the
effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the
effect of changes in tax law, such as the
effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the
effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
For its annual list, US News & World Report ranked 38 eating plans, considering different criteria including how easy the diet is to
follow, its
effects on weight loss (both short and long term), how nutritional and safe the diet is, and how well it helps prevent diabetes and heart
disease.
As we recognize the harmful
effects of taking synthetic medications and the benefits of
following a natural lifestyle, a lot of us are looking for ways to protect ourselves from different
diseases and trying to figure out how to fight them with natural remedies if we do become sick.
The official stance on medications and breastfeeding, supplied by the Center for
Disease Control and Prevention's (CDC) website, is as
follows: «Although many medications do pass into breast milk, most have no
effect on milk supply or on infant well - being.
Congenital infections also call for close medical
follow - up to watch for any
effects of the
disease that may develop as the baby grows.
An epidemiological study of PFOA
effects in West Virginia communties found a «probable link» between exposure to the chemical and the
following illnesses: diagnosed high cholestorol, ulcerative colitis, thyroid
disease, testicular cancer, kidney cancer, and pregnancy - induced hypertension.
This prevented severe
disease following antibody - enhanced infection when only virus was inoculated, but the protective
effect of the operation was lost when saliva was also present.
«If we can confirm selumetinib's effectiveness in treating advanced uveal melanoma in this
follow - up trial, it will become the standard therapy for this
disease, forming a foundation for new drug combinations that could maximize selumetinib's MEK - inhibitor
effect,» he said.
Williams said, the long - term
follow up allowed authors to examine dietary patterns and analyze the
effect of gradual adherence to a plant - based diet through reduced animal food intake and increased plant food intake on heart
disease risk.
Since the long - term health
effects experienced by children
following severe
disease likely differs from that of adults, researchers said that additional studies are needed to determine the health needs for children who survive EVD.
Called stereotactic body radiotherapy (SBRT), the study finds patients lived, on average, six to seven months longer
following treatment with minimal side -
effects even when they had other severe comorbidities such as chronic obstructive pulmonary
disease (COPD), heart
disease and diabetes.
Albertini replied that there might be subtle health
effects, such as early onset of adult
diseases like diabetes and cancer, that won't appear until 15 or 20 years after IVF, and he pointed out that there is very little
follow - up data on the health of children created through assisted reproductive medicine.
The risk of a febrile seizure
following the MMR is approximately one case in 3,000 doses for children aged 12 to 15 months but one case in 1,500 doses for children aged 16 to 23 months «This study adds to the evidence that the best way to prevent
disease and minimize side
effects from vaccines is to vaccinate on the recommended schedule,» says Simon Hambidge, lead author of the study and the director of general pediatrics at Denver Health.
We report a variety of biallelic
effects on organismal phenotype attributable to combinations of recessive Xpd alleles, including the
following: (i) the ability of homozygous lethal Xpd alleles to ameliorate a variety of
disease symptoms when their essential basal transcription function is supplied by a different
disease - causing allele, (ii) differential developmental and tissue - specific functions of distinct Xpd allele products, and (iii) interallelic complementation, a phenomenon rarely reported at clinically relevant loci in mammals.
We found no coding mutations that
followed the risk or non-risk haplotypes suggesting that regulatory mutations exert the
effect on
disease.
Effect of fetal neural transplants in patients with Huntington's
disease 6 years after surgery: a long - term
follow - up study.
examines long - term sequelae resulting from a diagnosis of childhood cancer and its treatment, and health care relating to these late
effects.This multi-study initiative is funded by a Canadian Cancer Society program project grant, with additional funding from CCS BC and Yukon Division, and has examined long - term health
effects and educational attainment, health care utilization, and quality of
follow - up care among
disease survivors.
Cook NR, «Long term
effect of dietary sodium reduction on cardiovascular
disease outcomes: observational
follow - up of the trials of hypertension prevention.
For example, Alzheimer's, cardiovascular
disease, and cancer (from the last bullet point)
follow the same pattern: they are not necessarily caused by excess carbohydrate consumption, and yet excess carbohydrate consumption exacerbates their negative health
effects as surely as it does those of Type I diabetes.
Published last week, it outrageously stated the
following: «Because coconut oil increases LDL cholesterol, a cause of cardiovascular
disease, and has no known offsetting favorable
effects, we advise against the use of coconut oil.»
One of my fears is that when this starts to happen, when the hundreds of thousands or millions of people
following these diets develop bad
effects, such as colon cancer, and other metabolic distortions, and diverticular
disease, conventional thinkers will say: «see we told you all those fad diets don't work and they're gonna be dangerous» they're going to label more rational approaches, like our approach, the Undoctored or the Wheat Belly approach as just a fad, when it's not.
We reported this to the Food Standards Agency, who have taken action to notify Cow & Gate of labelling requirements and issued the
following statement: In light of advice from the Scientific Advisory Committee on Nutrition on the adverse
effects of trans fats on the risk of coronary heart
disease, the Agency welcomes the voluntary action by the UK food industry to reduce the levels of artificial trans fats in our foods.
Thus we found the
following results: primary prevention is a powerful weapon against this kind of
disease and applying correctly in our daily freak miraculous
effects that has aroused the interest of scientists in various places around the world.
Complications and severity of side
effects varies from dog to dog, geography, epidemiology of a
disease, failure due to mishandling and by not
following protocols of vaccination.
Another less common side
effect is the development of immune mediated
disease following vaccination.
If your pet is born with the genes that make it susceptible to hip dysplasia,
following my advice regarding feeding, nutrition and exercise should be helpful in preventing, controlling or minimizing the
effects of this debilitating
disease.
Ten grants will be awarded to pre-proposals focusing on the health
effects of animals on humans with the
following conditions: autism, cancer, cardiovascular
disease, dementia / Alzheimer's, depression, post-traumatic stress disorder (PTSD), or childhood allergies and immunity.
At the time his death, on May 18, 2012, he was penning the autobiographical Close to the Bone, a book about his fifteen + year relationship with multiple myeloma (bone cancer), the treatments that
followed, and the
effects the
disease and modern medicine had upon his life and spiritual beliefs.
This conclusion is further supported by... the witnesses» evidence, found, inter alia, that «One of the
effects of criminal sanctions against homosexual acts is to reinforce the misapprehension and general prejudice of the public and increase the anxiety and guilt feelings of homosexuals leading, on occasions, to depression and the serious consequences which can
follow from that unfortunate
disease.»