Sentences with phrase «effects levels require»
More problematic is the Dolby Digital 5.1 audio, whose mismatched dialogue and effects levels require a constant riding of the remote control.
http://www.filmfreakcentral.net/ Not exact matches
Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.
Tax reform of this magnitude is the biggest change we've seen in a generation and will require intense focus to understand not only how the changes apply at the federal level, but also to navigate the ripple effect this is likely to have on state taxation as well.
Cities are projected to require at least USD 1.7 trillion a year for climate change mitigation and adaptation above business as usual in order to align GHG levels with those that limit global warming to 2 °C and avoid the worst effects of climate change.
Offer vs. Serve is still in effect... in fact, it is required at the high school level.
The institution of ratification grants states the necessary time - frame to seek the required approval for the treaty on the domestic level and to enact the necessary legislation to give domestic effect to that treaty.
WHEREAS, in furtherance of the united effort to address the effects of climate change, in 2010 the 16th Session of the Conference of the Parties to the UNFCC met in Cancun, Mexico and recognized that deep cuts in global greenhouse gas emissions were required, with a goal of reducing global greenhouse gas emissions so as to hold the increase in global average temperature below 2 °C above pre-industrial levels;
I hope they will aim to raise the initial tax threshold to the current subsistence level (even if over a few years), simplify the benefit system so that benefit claimants receive in effect a weekly wage or monthly salary instead of a number of dribs and drabs (all of which require horrendous forms), amalgamate NI with IT and then look at introducing a flat tax to cover the lot.
We should also note that serotonin treatment had no effect on milk yield, feed intake or on levels of hormones required for lactation.»
Researchers» recommendations: Implementing instruments to combat urban sprawl to maximum effect requires a high level of regional coordination.
Now a study has found that the gene mutation's toxic effects require higher than normal levels of a protein called suPAR to trigger the onset and progression of the disease.
To avoid the white coat effect, at - home automatic measurements taken by the patient may be required, but available oscillometry - based automatic meters offer a low level of accuracy.
Foods designed to have novel compounds or altered levels of natural substances require a special attention for unintended health effects, the committee concluded.
Across studies of animals — from rats to frogs to marine mammals — plasma levels, time required to eliminate PFAAs from the body, and health effects vary greatly, making it difficult to extrapolate from one species to another.
«This requires an interdisciplinary effort, for example through long - term experiments that examine the effects of multiple drivers over many generations at the community level.
Vitamins and minerals are required for sustaining optimal health, but few of them also have a positive effect on your anabolic hormone levels.
Circuit training also triggers a significant EPOC effect, which is the amount of oxygen required to restore your body to its normal, resting level metabolic function.
However, in my personal experience using this approach to «starve» my brain tumour, I find I can become quite the data junkie, measuring blood levels of both glucose and ketones up to four times a day, because in my mind, the optimal levels of both are perhaps what's required to have a therapeutic effect.
They require other compounds to work in synergy to be able to sufficiently enhance Growth hormone levels if used in small amounts, especially ingredients that can block Somatostatin, otherwise the effect of amino acids is only going to be minimal.
Basically, your body becomes so used to excess sugar, that the normal levels of insulin required to counteract the effects of the sugar are no longer enough.
While more research is required, it looks as though Ashwagandha's effect on insulin secretion and sensitivity could be harnessed to help reduce blood sugar levels.
Although ketoacidosis — acidification of the blood due to pathological levels of ketones — was historically proposed as a side effect, nutritional ketosis simply can not achieve the level of ketones required to induce this life - threatening state.
A certain level of technical competence is required for the «squat more, lift more» motto to be in effect.
This is required in the conversion of cholesterol into testosterone; therefore, a low level of this vitamin causes a direct effect on testosterone levels.
Everything you eat has a thermic effect, which refers to the energy level it requires for your body to process it.
Furthermore, this harmful effect of fructose does not require high blood glucose or blood insulin levels to wreak havoc.
Although the effects of arginine on blood flow, protein synthesis, and exercise performance require further investigation, dosages commonly consumed by athletes are well below the observed safe level of 20 g / d and do not appear to be harmful [182].
«Even mild dehydration that can occur during the course of our ordinary daily activities can degrade how we are feeling — especially for women, who appear to be more susceptible to the adverse effects of low levels of dehydration than men,» says Harris Lieberman, one of the studies» co-authors and a research psychologist with the Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine in Natick, Mass. «In both sexes these adverse mood changes may limit the motivation required to engage in even moderate aerobic exercise.
Specification points covered are: Paper 2 Topic 1 (4.5 - homeostasis and response) 4.5.1 - Homeostasis (B5.1 lesson) 4.5.3.2 - Control of blood glucose concentration (B5.1 lesson) 4.5.2.1 - Structure and function (B5.2 lesson) Required practical 7 - plan and carry out an investigation into the effect of a factor on human reaction time (B5.2 lesson) 4.5.3.1 - Human endocrine system (B5.6 lesson) 4.5.3.4 - Hormones in human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9Required practical 7 - plan and carry out an investigation into the effect of a factor on human reaction time (B5.2 lesson) 4.5.3.1 - Human endocrine system (B5.6 lesson) 4.5.3.4 - Hormones in human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9 lesson)
It was a mutual effort to learn from each other the effect of which was to show there is a degree of normality in the country and, despite a high level of security awareness required for the trip, the school found stereotypes could quickly be cast aside.
Separating out the effect of race matching from differences between schools requires individual - level data on students and teachers, including their race and exposure to school discipline measures over multiple years.
Focusing on secondary level education, frequent feedback from teachers on shorter homework tasks has a larger impact upon progress, open - ended projects require time and have a lower effect on overall progress.
The top 3 levels require findings of a statistically significant effect on improving student outcomes or other relevant outcomes based on and are mandatory for school improvement plans funded by 7 % set aside (Section 1003):
The guarantee, which takes effect this year, requires that students read at grade level or better in order to graduate to fourth grade.
Child Trends, Inc.; Washington D.C. $ 283,000 over two years to investigate children's access to highly - qualified ECE professionals and identify potential disparities in certain geographic areas, analyze the effects of recent state - level workforce policies and funding decisions on the ECE workforce in two states, and develop a forecasting tool that state leaders can use to estimate the potential cost / time factors required to implement ECE workforce development policies.
This study examines the effects of grade retention on student misbehavior in Florida, which requires students with reading skills below grade level to be retained in the 3rd grade.
The «Read to Achieve» program, which went into effect this year, requires all third - grade students to read at grade level or risk being held back.
Airport development means --(1) Any work involved in constructing, improving, or repairing a public airport or portion thereof, including the removal, lowering, relocation, and marking and lighting of airport hazards, and including navigation aids used by aircraft landing at, or taking off from, a public airport, and including safety equipment required by rule or regulation for certification of the airport under section 612 of the Federal Aviation Act of 1958, and security equipment required of the sponsor by the Secretary by rule or regulation for the safety and security of persons and property on the airport, and including snow removal equipment, and including the purchase of noise suppressing equipment, the construction of physical barriers, and landscaping for the purpose of diminishing the effect of aircraft noise on any area adjacent to a public airport; (2) Any acquisition of land or of any interest therein, or of any easement through or other interest in airspace, including land for future airport development, which is necessary to permit any such work or to remove or mitigate or prevent or limit the establishment of, airport hazards; and (3) Any acquisition of land or of any interest therein necessary to insure that such land is used only for purposes which are compatible with the noise levels of the operation of a public airport.
The net effect of this is therefore that a completely uneducated, common - Joe investor can enjoy the same level of diversification as wealthy sophisticated investors who can create private portfolios requiring hundreds of thousands or even millions of dollars.
The Dividend Rate and Annual Percentage Yield are fixed and will be in effect for the initial term of the account so long as the required products and services applicable to the relationship levels are maintained.
Cats with exceptionally high potassium levels may require medications immediately to rapidly lower the potassium level and prevent adverse effects on the heart.
This could be a problem in patients with congestive heart failure or other patients who require sodium restriction May stunt growth if used in young, growing animals May lower seizure threshold and alter mood and behavior At high doses, this medication can cause birth defects early in pregnancy, be irritating to the stomach or cause higher than normal blood sugar levels If your pet has received high doses, it should not be vaccinated without your veterinarian's advice as the vaccine may not work or it may actually give your pet the disease you are trying to prevent Less common side effects include weight gain, insomnia, panting, diarrhea, vomiting, elevated liver enzymes, pancreatitis and behavior changes Serious side effects are not expected with routine use.
Here is an example of the amounts of different types of chocolate (in ounces) that a 10 - pound cat would need to consume in order to experience toxic effects (smaller cats and kittens require much smaller amounts to reach toxic levels):
It reaches its peak blood level in 3 to 6 hours in cats but may require a full 12 hours in dogs to reach its full effect.
That additional puzzle that changes the map is basically the easiest one as well, ones in later levels require you to hit / destroy multiple objects which have varying effects — mainly zombie killing effects though.
Today, BioWare and Electronic Arts have revealed their recommended Mass Effect: Andromeda system requirements, giving you an idea of the performance required to enjoy the game at a high level of detail at 1920x1080, the most popular gaming resolution.
A Colombian location shoot should lend the film — at least the parts not requiring lots of special effects — a certain level of authenticity.
Spokesman Niels Peter Nørring stated, «A climate tax would require a massive setup in the public sector and the food industry while the effects would be minimal,» adding that climate change can only be addressed at a global level.