Sentences with phrase «effects of a given drug»

Building on each subsequent experiment, researchers using Valdar and Lenarcic's methodology could eventually pinpoint which genetic variations play roles in the side effects of a given drug.

Not exact matches

To balance out the effects of men's low testosterone levels while taking the drug, the patients were given a synthetic androgen, or male steroid hormone, to help them maintain their «male» characteristics.

For future studies, they suggested, researchers should test the performance of doped chess players given a much longer time limit, so the study could isolate the positive effects of brain drugs.

It tells the story of «the guinea pigs»» the people most likely to be research subjects in Phase I trials, which test the safety of a drug under development by giving it to healthy subjects and examining any side effects they experience.

For instance, it is remarkable how little attention is given to the effects of alcohol, drugs, and tranquilizers on the lives of church members.

The conclusion: given relatively unlimited availability, heroin users will voluntarily stabilize or reduce their dosage and some will even choose abstinence; long - addicted users can lead relatively normal, stable lives if provided legal access to their drug of choice, and with few side effects; and ordinary citizens (in Switzerland at least) will support such initiatives.

Drugs used in active management have documented risks for the mother, including death, and we do not know the long - term effects of these drugs, which are given at a critical stage of brain development, for the Drugs used in active management have documented risks for the mother, including death, and we do not know the long - term effects of these drugs, which are given at a critical stage of brain development, for the drugs, which are given at a critical stage of brain development, for the baby.

Garrison (personal communication) reports that Narcan, which is sometimes needed by the baby to counteract the sedating effect of pain - relieving drugs such as pethidine (demorol), given to the mother in labour, can be effectively administered via the mother's veins in third stage, waking up the newborn baby in a matter of seconds.

The pregnancy section would outline any known risks a given drug may pose to a fetus, while the lactation section would list any known details about «the drug's impact on milk production, what is known about the presence of the drug in human milk, and the effects on the breast - fed child.»

A 2013 study on the transfer of drugs into human milk, published in the American Academy of Pediatrics (AAP) News & Journal, explains how women who are advised to stop nursing when taking medications are given this advice because of the largely errant belief that the drugs may have negative effects on their babies.

But given that the most pernicious effect of the state's drug laws remains the extraordinary volume of low - level marijuana arrests — an expensive habit Cuomo has made noise about correcting in the past — his new executive order is most noteworthy for what it does not do.

Community members were given free Naloxone kits, as well as instructions on how to properly administer the life - saving drug that reverses the effects of opioid overdose.

But when Rafi Ahmed and colleagues at Emory University School of Medicine in Atlanta, Georgia, gave the drug to mice infected with a virus, to probe its effects on specific parts of the immune system, they found it can have another effect.

«Given the cost and potential side effects associated with pregabalin, it is critical that we understand the efficacy of this drug,» Markman said.

The main purpose of phase I clinical trials are to evaluate the safety of a new drug, helping researchers determine the maximum dose that can be given safely as well as any harmful side effects.

Giving the bees a drug to block the neurochemical dopamine, which is related to the reward system in humans, largely reversed the effects of the treat, indicating that these effects were down to dopamine making them feel good.

Those suspected of having TB may also be given potent antibiotics as a precaution — drugs that can cause serious side effects, including vomiting, headaches, rash and drug - induced hepatitis (liver inflammation).

In a paper published online by the New England Journal of Medicine, investigators at Dana - Farber and research centers around the world found that the drug combination — given as a single pill known as TAS - 102 — not only extended patients» overall survival, but also delayed the advance of the disease and did so with very few side effects.

In a double - blind study, the participant may come to realise that he or she has been given the drug instead of placebo because of the experienced side effects, and this may in turn result in increased expectations of improvement and a better effect is reported.

Many researchers believe that psychedelic effects are driven in large part by expectations of the experience so neither monitors nor subjects knew when they would be given the psychoactive drug.

New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that's used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline.

«By understanding the mechanisms for these noxious effects,» says Hugh Hemmings, a professor of anesthesiology at Weill Cornell Medical College in New York City, «it gives you a way to screen for new drugs that don't have these effects, but do produce anesthesia.»

Only about a third of people with such symptoms do go on to develop psychosis, however, and antipsychotic drugs can cause nasty side effects, so these are rarely given as a preventative.

However, if SSRIs had indeed acted merely by means of a placebo effect, these drugs should not outperform actual placebo in clinical trials where patients have been treated with an SSRI or with ineffective placebo pills, and where neither the physician nor the patient knows which treatment the patient has been given until the study is over.

By giving an experimental drug along with a narcotic, a team of researchers has eliminated the opiate's potentially lethal side effect while preserving its ability to blunt pain.

Think of it like this: if you want to study the effect of a drug, then you could theoretically give the drug to a random person and a placebo to another random person.

This therapeutic effect was enhanced by combining the Angiopoietin - 2 antibody with a so - called metronomic chemotherapy: In this kind of therapy, chemotherapeutic drugs are given continuously at much lower dose as in the classical high - dose chemotherapy.

«Perhaps giving a person the right dose, at just the right time, of a drug with just the right pharmacokinetic properties so its effect will wear off at the right time would work a lot better than bombarding the brain with benzodiazepines, such as Valium, that knock out the entire brain.»

Frequent tanners experience withdrawal symptoms when given a drug that overrides the effects of opioids, chemicals that can be naturally produced by the body and generate feelings of euphoria.

«This means we can put people on the right medications sooner, spare them the toxic effects of drugs that are ineffective and prevent the development of drug resistant forms of TB that can occur when the wrong medications are given.»

It is worthwhile to give patients expensive new drugs that can cure their hepatitis C much earlier than some insurers are now willing to pay for them, according to a UC San Francisco study that models the effects of treating the disease early versus late in its development.

Perhaps that's not surprising given that the U.S. Office of National Drug Control Policy reports that more than 2 million Americans used cocaine in 2007, which has been linked to ill effects ranging from debilitating addiction to heart attacks.

They found that if mice exposed to bloodstream infections were given a drug that mimics the effect of low oxygen, levels of HIF2alpha and VE - PTP rose and their blood vessels became less leaky.

Previous research, for example, has shown that a majority of never - smokers given a cigarette or dose of nicotine not only report disliking the effects, but later, when offered a nicotine - containing pill, gum or candy, or a placebo — a classic test of the «reinforcement» abilities of an addictive drug — they chose the placebo.

When given in combination, however, the two drugs had a strong synergistic effect and caused cell death across a wide range of concentrations.

However, treatments of psychiatric disorders (e.g., drugs and cognitive behavior therapy) could not increase or decrease a specific connectivity between two regions, because these methods give broad effects on the global network.

Because high doses of opioids have the potential to cause respiratory arrest or other dangerous side effects, doctors may hesitate to give patients as much of the drugs as they need to relieve their pain, says David Soergel, chief medical officer at Trevena.

«More research is needed into the effects of nicotine addiction on the adolescent brain, given converging evidence from other drugs of addiction that exposure during this key developmental period can have lasting effects on the brain extending into adulthood.»

History provides us with many examples of drugs that seemed like a good idea, but had unexpected side effects when given to people.

SciLifeLab gave her a call to learn more about how her team contributes to the understanding of why some people get severe adverse effects from medical drug treatments while others do not.

In fact, scientists suspect that the mood - improving effects of antidepressant drugs and physical exercise arise at least in part from the boost they give to DG neurogenesis.

Patients taking Haldol also were given another drug to prevent tremors and other Parkinson's - like side effects of Haldol; that drug also costs pennies a day.

«Given that aspirin is a cheap, off - patent drug with relatively few side effects, this will have a great impact on health care systems as well as patients,» study lead author Dr. Martine Frouws, of Leiden University Medical Center in the Netherlands, said in a news release from the European Cancer Congress (ECC).

I did try some of the drugs Entocort and Pentasa, I knew the side effects weren't to bad with these particular drugs so I gave it a try.

The medication gave her a whopping headache, a common side effect of the drug.

By this time, the film «First Do No Harm» had been made highlighting the Ketogenic Diet, but when I questioned the doctors, again, I was told it was «Hollywood hype» and the diet really didn't work that well and that this film did not give the details of all the terrible side effects that there were with the Ketogenic Diet and once again I was told that drugs were the best option.

These new biologic drugs, or drugs of any sort, given to a 14 yr old boy for an unlimited amount of time seems careless when there's no other discussion about other healthier alternatives that have less side effects.

The efficacy and necessity of these drugs has long been debated in the natural health world — mainly questioning whether the absolute benefit of the drug justifies the lifetime prescription or whether the approach of «blocking» cholesterol makes sense given that cholesterol is vital for so many other areas of human health — but for those that do decide to take Lipitor, Crestor or other statins, it's important to consider the drug's other effects on the body.

Vitamins, minerals, amino acids and certain other nutrients can have an incredibly potent drug - like effect when given directly into a vein, but without the side effects of many prescription medications.

Side effects from drugs given outside of hospitals may cause an additional 199,000 deaths / year.