Sentences with phrase «effects of inflammation in»

By feeding your dog an anti-inflammatory diet (one very low in carbohydrate content), you can help reduce or moderate the effects of inflammation in your pet's body, including the joints.

The polyphenolic compounds and phytochemical substances found in walnuts reduce the effects of inflammation in the body.

Removal of the spleen protected mice from the effects of inflammation in heart failure.

Not exact matches

In 2007, Dr. Rikke Krogh - Madsen, a post-doctoral fellow at the Centre of Inflammation and Metabolism in Copenhagen, decided to test the effects of a sedentary lifestylIn 2007, Dr. Rikke Krogh - Madsen, a post-doctoral fellow at the Centre of Inflammation and Metabolism in Copenhagen, decided to test the effects of a sedentary lifestylin Copenhagen, decided to test the effects of a sedentary lifestyle.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

When inflammation strikes, we are conditioned into reaching for a quick fix in the way of pharmaceutical or prescribed drugs such as aspirin and ibuprofen, temporary panacea's that come with their own adverse side effects and with long term use have the potential to create a host of health problems independently.

Because the toxicity is associated with oxidative stress and inflammation, the study explored antioxidant and anti-inflammatory effect of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.

In fact, one of the primary studied benefits in this regard is the effect that cacao has on improving insulin resistance and downregulating inflammation caused by obesity (6In fact, one of the primary studied benefits in this regard is the effect that cacao has on improving insulin resistance and downregulating inflammation caused by obesity (6in this regard is the effect that cacao has on improving insulin resistance and downregulating inflammation caused by obesity (6).

ST. LOUIS, Nov 14, 2011 — A study published online in Hormone and Metabolic Research showed the positive effects of soy protein isolate in obesity - related conditions such as inflammation and fatty liver disease.

I went looking for it since I see you use it so much and thought it must be great, and found it has Carrageenan in it, which is believed by some to cause inflammation and a list of other supposed effects.

One of my favorite antioxidants they contain is quercetin which can help decrease the inflammatory effects of chemicals in the synovial fluid of the joints for people with inflammatory conditions such as rheumatoid arthritis and other forms of chronic inflammation.

As much as I appreciate the effects of natural melatonin supplies, I am even more swayed by recent studies that indicate that the powerful antioxidants in cherries can play a role in reducing inflammation.

Results: Daily ingestion of wheat - based starch hydrolysates, glucose syrups and maltodextrins, had no deleterious effect on small - bowel mucosal villous architecture or inflammation in coeliac disease patients when compared to the placebo group.

Histidine is another amino acid precursor to a mediator of inflammation, histamine; would the restriction of histidine in the diet have a longevity promoting effect, too?

To investigate the effect of various parenting styles on kids» health, researchers at the University of Oregon examined saliva samples of 102 children who had an average age of 9 to look for levels of C - reactive protein, which measures general inflammation in the body, and secretory immunoglobulin A, which measures immune system activation.

While we don't know the long - term effects of unhealthy fats on infant cardiovascular health, we do know that in adults these fats negatively affect heart health by raising LDL (bad cholesterol), lowering HDL (good cholesterol), and increasing signs of inflammation.

The effects of antibiotics on toothache caused by inflammation or infection at the root of the tooth in adults

In addition, many studies do not take into account the complex interaction of different fatty acid subtypes, such as omega - 3 and omega - 6 fatty acids, on gut inflammation as well as their effect on the intestinal microbiome.

E-cigarette vapors also «produced mild effects on the lungs, including inflammation and protein damage,» notes Thomas Sussan of the Johns Hopkins Bloomberg School of Public Health, lead author of the study, published February 4 in PLOS ONE.

«Our research suggests that in mice, males may be more vulnerable to the effects of maternal inflammation than females, and the impact may be life long,» says study leader Irina Burd, M.D., Ph.D., an assistant professor of gynecology / obstetrics and neurology at the Johns Hopkins University School of Medicine and director of the Integrated Research Center for Fetal Medicine.

For the study, researchers sought to mimic the effects of a maternal infection or other condition that causes inflammation in a pregnant mother.

In addition, the development of therapies that could potentially halt patients» progression from pancreatic inflammation to diabetes has been hampered by the long lead times needed in order to tell whether a given therapy has an effecIn addition, the development of therapies that could potentially halt patients» progression from pancreatic inflammation to diabetes has been hampered by the long lead times needed in order to tell whether a given therapy has an effecin order to tell whether a given therapy has an effect.

One of the side - effects of this therapy is autoimmune intestinal inflammation — analogous to the inflammation that occurs in patients with the CTLA - 4 gene mutation.

A third group first got an injection of a compound known to block the effects of interleukin - 1 beta (IL - 1), a protein involved in activating the inflammatory immune response and shown in previous research to be a key player in modulating fetal brain injury following exposure to inflammation in the womb.

Disease - driving mechanisms vary and include, among others, the pruning of neuronal synapses, effects on CNS development in utero, and inflammation.

«Actively treating bodily inflammation in middle age and beyond may lessen the effects of these conditions on the brain's decline in old age.»

«They have proven effective in combating acne by reducing extremely high levels of acne - causing bacteria, and have other inflammation - dampening effects.»

The potential strategy — which targets metabolic pathways that are active only during intestinal inflammation — prevented or reduced inflammation in a mouse model of colitis while exerting no obvious effect in control animals with healthy, balanced bacterial populations, said Dr. Sebastian Winter, Assistant Professor of Microbiology and co-corresponding author of the study published online today in Nature.

But in 2005 scientists discovered that oleocanthal — the naturally occurring compound that elicits a peppery, burning sensation in the back of the throat — seemed to produce effects strikingly similar to those of ibuprofen, which tamps down inflammation.

Dylan Ryan added: «We've found that itaconate can directly modify a whole host of proteins important for inflammation in a chemical reaction never before described, and that this reaction is important for the anti-inflammatory effects of itaconate.»

But any new therapy can also cause undesirable effects: In our experiments, we saw that blocking apoptosis under inflammatory conditions can result in bililary obstruction (cholestasis) in the context of liver inflammation.&raquIn our experiments, we saw that blocking apoptosis under inflammatory conditions can result in bililary obstruction (cholestasis) in the context of liver inflammation.&raquin bililary obstruction (cholestasis) in the context of liver inflammation.&raquin the context of liver inflammation.»

Dr. Wang plans to continue studying the effects of TNF and IL - 17 on melanocytes, and would like to expand the research to 3D skin models — fabricated samples of tissue in vitro that behave like human skin — that would give a better visual of how the melanin production process is being disrupted by these two cytokines during skin inflammation or wound healing.

In particular, drugs that inhibit production of prostaglandin E2 may curb inflammation and tumor growth, while avoiding the cardiovascular side effects of drugs such as Vioxx and the gastrointestinal problems of the earlier class of NSAIDs.

Activation of NOTCH1 by blood flow causes a domino effect, triggering numerous other genes in the network to turn on or off, resulting in suppression of inflammation and calcification.

The findings suggest that by promoting chronic inflammation through their effect on fat cells, staph superantigens may play a role in the development of diabetes.

Although the reasons why colonoscopy increases the risk of appendicitis remain unclear, the article offers some theories, including asking if bacteria within the colon are altered as the bowel is prepared prior to colonoscopy in ways that increase the likelihood of inflammation, or if the increased air pressure caused by colonoscopy may have effects on the colonic mucosa that can predispose people to appendicitis.

For most available T cell immunotherapies, T cells (which play a central role in defending the body against illness) are engineered to recognize and eliminate tumors, but their activity is not specifically controlled, leading to toxicity and unwanted side effects in patients as a result of inflammation or in some cases suboptimal response to treatment.

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the conditioIn a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the conditioin mice with Crohn's - like disease, but had no substantive effect on those without the condition.

«We know that amlexanox works to reverse obesity and insulin resistance in part by resolving chronic inflammation and increasing energy expenditure, but that's not the whole story of the drug's effects,» said Shannon Reilly, first author of the study.

A new study using two multiple sclerosis (MS) models published in The American Journal of Pathology has found that resveratrol actually worsened MS - like neuropathology and inflammation and had no neuroprotective effects.

However, although the ultrathin films and rubber sheets used in these devices adhere and conform well to the skin, their lack of breathability is deemed unsafe for long - term use: dermatological tests show the fine, stretchable materials prevent sweating and block airflow around the skin, causing irritation and inflammation, which ultimately could lead to lasting physiological and psychological effects.

In addition to effects on the brain, Brody's research with the SAAF participants has found they have lower levels of stress hormones circulating in their bodies, they have lower levels of inflammation, and they are less likely to show biological markers of premature aginIn addition to effects on the brain, Brody's research with the SAAF participants has found they have lower levels of stress hormones circulating in their bodies, they have lower levels of inflammation, and they are less likely to show biological markers of premature aginin their bodies, they have lower levels of inflammation, and they are less likely to show biological markers of premature aging.

Studying the effects of oxygen - sensing proteins in immune cells is especially relevant for patients who often have low levels of oxygen in their body and chronic lung inflammation.

Most products on the market today that are used to treat skin problems target the effects of the disease or wound such as inflammation, which can prolong the healing process and result in scarring.

These trends may be explained in part by the yo - yo effects that high glycemic - index carbohydrates have on blood glucose, which can stimulate fat production and inflammation, increase overall caloric intake and lower insulin sensitivity, says David Ludwig, director of the obesity program at Children's Hospital Boston.

Looking beyond provocative findings like those in Finch's study, Tracy and other researchers on aging say that it may be too simplistic to think of inflammation in terms of straightforward cause and effect.

In addition to cholesterol, eggs contain many beneficial nutrients that can have an effect on, for example, glucose metabolism and low - grade inflammation, and thus lower the risk of type 2 diabetes.

The disease is largely attributed to an abnormal buildup of proteins, which can form amyloid beta plaques and tangles in the brain that trigger inflammation and result in the loss of brain connections called synapses, the effect most strongly associated with cognitive decline.

We hope that by understanding the processes involved in inflammation we will herald the arrival of new and targeted anti-inflammatory drugs that have fewer side effects than what is currently available.»

Inflammation from pain and injury raises acidity, so this molecule could quash pain where necessary, but wouldn't bind to receptors elsewhere in the body, reducing the likelihood of side effects.