Sentences with phrase «effects of the treatment included»

Side effects of the treatment included skin rashes, thyroid problems and diarrhea as the therapy caused the immune system to attack other parts of the body.
Side effects of the treatment included hot flashes, heart palpitations, and burning sensations in the skin, which were reversed by adjusting the DBS settings, according to the study.

Not exact matches

CAR - T treatments, including competing products from Novartis rivals Kite Pharma and Juno Therapeutics, come with the risk of potentially deadly side effects such as cytokine - release syndrome (CRS), in which a glut of T - cell - assisting cytokines can cause high fever, low blood pressure, and problems with lung oxygenation.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Contraindications of TEOSYAL ® PURESENSE treatments include pregnancy and breast feeding since the effect of the injections in these circumstances is not known.
Examples might include a 30 - year - old healthy woman without a family history of ovarian cancer wanting to have her ovaries removed to prevent such a cancer; a woman with fibroids wanting an experimental surgical treatment whose long - term effects are still unknown; or an 18 - year - old woman without children wanting a sterilization procedure.
While HELLP syndrome is rare, effecting only 1 or 2 out of every 1000 births, without early treatment HELLP syndrome carries with it a high risk of severe health complications, including death, for the mother and fetus.
In a trial that included separate treatment groups of nurse and paraprofessional home visitors, the nurses produced effects that were twice as large as those of the paraprofessionals.18
In future updates, if more eligible studies are included, we will explore the impact of including studies with high levels of missing data in the overall assessment of treatment effect by using sensitivity analysis.
The difference in the average treatment effect in overall fetal loss and neonatal death across included trials between women allocated to midwife - led continuity models of care and women allocated to other models has an average risk ratio (RR) of 0.84, with 95 % confidence interval (CI) 0.71 to 0.99 (participants = 17561; studies = 13).
The difference in the average treatment effect in all fetal loss before and after 24 weeks plus neonatal death across included trials between women allocated to midwife - led continuity models of care and women allocated to other models has an average RR of 0.84, with 95 % CI 0.71 to 0.99.
The difference in the average treatment effect in all fetal loss before and after 24 weeks plus neonatal death across included trials between women allocated to midwife - led continuity models of care and women allocated to other models has an average risk ratio (RR) of 0.84, with 95 % confidence interval (CI) 0.71 to 0.99 (participants = 17561; studies = 13).
In future updates we will explore the impact of including studies with high levels of missing data in the overall assessment of treatment effect by using sensitivity analysis.
And at this year's conference, sessions included «Avoiding Unnecessary Guilt When Breast - Feeding Does Not Happen,» «Medications & Mother's Milk,» «The Effect of Media Violence on Children» and «Complementary Treatments to Postpartum Depression.»
The difference in the average treatment effect in overall fetal loss and neonatal death across included trials between women allocated to midwife - led continuity models of care and women allocated to other models has an average risk ratio (RR) of 0.84 and a 95 % confidence interval (CI) of 0.71 to 1.00 (12 trials, n = 15,869, RR 0.84, 95 % CI 0.71 to 1.00, random - effects).
Again, there was some evidence that the treatment effect may be partly due to bias; sensitivity analysis including only those studies assessed as being at low risk of bias for allocation concealment showed that results still favoured the intervention group although the treatment effect was less pronounced in the studies at lower risk of bias (Analysis 1.8).
Topics include the rights of persons with disabilities; the rights and responsibilities of drug users and ethical considerations for dignified addiction treatment; improving maternal and child health through advancements in women's rights; the effects of violence; access to affordable and appropriate health care and treatment; health disparities between different population groups; health during war and conflict; the health of internally displaced persons and refugees; and recognition of social and structural forces that impact the health of individuals and groups.
«Most researchers have relied on cell lines to screen the effect of drugs and other treatments including viruses,» said Dr. Cripe, who also is a professor at The Ohio State University College of Medicine.
«Given the current state of the opioid overdose epidemic, it is critical that patients seeking help for opioid addiction have access to comprehensive treatment that includes highly effective medications whose effects may be enhanced with the provision of psychosocial interventions,» according to the report by Karen Dugosh, PhD, of Treatment Research Institute, Philadelphia, and ctreatment that includes highly effective medications whose effects may be enhanced with the provision of psychosocial interventions,» according to the report by Karen Dugosh, PhD, of Treatment Research Institute, Philadelphia, and cTreatment Research Institute, Philadelphia, and colleagues
While lithium carbonate has been very effective for the treatment of mania in bipolar disorder, and credited for reducing suicides in depressive phases of the disease, patients who take lithium carbonate are often noncompliant because of adverse effects, including hand tremor, diarrhea, vomiting, weight gain and decreased thyroid function.
Whilst they are highly effective, they also have numerous disadvantages: in some cases treatment had to be abandoned due to acute side effects, including marked increases of liver enzymes, with the result that CGRP receptor antagonists have not been approved to date.
New findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments.
New findings by a biomedical engineer and his team at the University of Houston (UH) raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease.
Possible long - term interventions to reduce mortality and morbidity after high exposures end include disease screening, reducing important co-exposures, treatment and health services resource planning, and increasing public awareness of arsenic health effects.
The authors address difficulties that arise from conditions of field implementation, including the estimation of treatment effects under partial treatment implementation, the prevention and analysis of attrition, analysis of nested designs, new analytic developments for both regression discontinuity designs and short interrupted time series, and propensity score analysis.
According to researchers, antibiotic resistance and side effects limit the efficacy of the current treatments, which include benzoyl peroxide, retinoids, antibiotics and Accutane (isotretinonin).
The researchers continue to study the effects of treatment in both mice and dogs, improve the photoswitch, and develop ways of attaching the photoswitch to other receptors, including some that could amplify the signal and allow perception of fainter light, as occurs normally in rods and cones.
The paper, written by authors at King's College London and Baylor College of Medicine, reviews contraceptive devices available including those already used by military and aviation personnel, and calls for more research into the effect of hormone treatments on bone mineral loss in space.
Because loss of bone mineral density is known to occur on spaceflight missions, we need more data regarding health effects, including bone health, with long - term use of hormone treatments not just for contraception (as most women use them), but also for the less - common use to suppress menses.»
In addition to prevalence estimates, the reports also include data on cancer treatment patterns, survival, and information on common short - and long - term effects of cancer and its treatment for eleven selected cancers.
«While there are clearly other factors that can cause these types of abnormalities, including genetic vulnerabilities, demonstrating that immune activation alone can produce these effects offers new hope for treatments that might reduce their severity, or prevent them altogether, in certain individuals.»
If, for example, the crucial effects of neutrinos were included in some detailed treatment, the computer simulations could only be performed in two dimensions, which means that the star in the models was assumed to have an artificial rotational symmetry around an axis.
«This research is important because it identifies a way to reduce some of what, in medical treatment, are usually thought of as THC's unwanted side effects, while maintaining several important benefits including pain reduction.»
Both psychotic symptoms and treatment side effects are more extreme in other types of dementia, including Parkinson's Disease Dementia and Lewy Body Dementia.
But treatment to reduce 5HT2AR did not change other effects of THC, including pain relief.
And yet the majority of men who are diagnosed via a PSA test end up having treatment with a high risk of side effects including erectile dysfunction, urinary incontinence and heart attack.
Older traditional treatments that included interferon and ribavirin were less effective and caused a variety of side effects, including fatigue, as well as flu - like symptoms, depression and lowered blood cell counts.
Other projects include an analysis of regional variations of cancer treatment in Texas, a study of the effect of smoking bans on hospitalization rates, and a study of whether shared savings programs for physicians can reduce overall patient health care expenditures.
Survivorship includes issues related to health care access, follow - up treatment, late - and long - term effects of treatment, recurrence, and quality of life.
Active tuberculosis is treatable (and curable), but disease control and treatment adherence are complicated by a variety of factors, including availability of healthcare resources, multidrug - resistant tuberculosis strains and potentially toxic side effects of treatment.
The scientists also found that the surgery and radiation treatments sometimes caused severe side effects, including sexual dysfunction, incontinence and bowel problems, that hurt the patients» quality of life.
For example, mutants may be characterized by comparing their transcript profiles to those obtained in other experiments querying the effects on gene expression of many experimental factors including treatments, mutations and pathogen infections.
Written by two experienced oncology nurses, this compassionate and comprehensive guide explains in plain English everything you need to know about your treatment, including what you can expect at each stage of chemotherapy and what you can do to prevent or minimize side effects.
Differences in age, hearing level, duration of tinnitus of the included patients, and the condition of sham treatment may influence the effect.
Although effective in the treatment of anxiety, they can cause significant side effects, including orthostatic hypotension (drop in blood pressure on standing), constipation, urinary retention, dry mouth, and blurry vision.
Areas of focus include: understanding how tumour - reactive T cells and B cells promote patient survival in cancer; defining the effects of standard treatments on tumor immunity; and using genomic approaches to identify novel tumour mutations that can serve as target antigens for immunotherapy.
He also developed the first treatment protocol for MS involving the transplantation of stem cells in the U.S. Along with his peers, Dr. Kraft identified the importance of treating the secondary effects of MS, known as hidden disabilities, including cognitive impairments, pain, fatigue, sleep disturbance, and depression.
«A lot of the treatments have effects on sexual health,» Hill said, including hormone therapy and chemotherapy.
Her current focus is on developing clinical protocols for the treatment of head and neck and lung cancers with a goal of providing enhanced tumor control, including control of metastases, with minimal effect of quality of life.
Urinary problems, including frequency, urgency, incontinence and pain, are common in patients with prostate cancer, due to the disease itself, and as a side effect of cancer treatments like radiation and prostate surgery.
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