Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in
treatment duration; availability
of funding for state AIDS Drug Assistance
Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the
effect of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory
programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase
program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Cold Logic can address the
effect of oil fouling in refrigeration systems operating chillers, freezers and plate freezers through the use
of a refrigerant side
treatment program.
HIV Medicine DOI: 10.1111/j.1468-1293.2011.00918.x IBFAN - Asia Position Statement on HIV and Infant Feeding, 13 October 2008 South African Tshwane Declaration on breastfeeding, S Afr J Clin Nutr 2011; 24 (4) UNAIDS 2010, Strategy Getting to Zero, UNAIDS Strategy 2011 — 2015 UNAIDS 2010, Agenda for Accelerated Country Action for Women, Girls, Gender Equality and HIV, 2010 - 2014 UNAIDS 2011, Countdown to Zero: Global plan towards the elimination
of new HIV infections among children by 2015 and keeping their mothers alive, 2011 - 2015 UNAIDS 2011 Press Release, 9 June, World leaders launch plan to eliminate new HIV infections among children by 2015 UNICEF Convention on the Rights
of the Child UNICEF 2010, Facts for Life UNICEF 2011,
Programming Guide, Infant and Young Child Feeding, 26 May 2011 WHO / UNICEF 2003, Global strategy for infant and young child feeding WHO 2007, Evidence on the long - term
effects of breastfeeding: systematic reviews and meta - analysis WHO, UNAIDS, UNICEF 2009, Towards universal access: scaling up priority HIV / AIDS interventions in the health sector: progress report 2009 WHO 2009, Women and health, Today's evidence tomorrow's agenda WHO 2009, Acceptable medical reasons for use
of breast - milk substitutes WHO 2009, Rapid advice: use
of antiretroviral drugs for treating pregnant womenand preventing HIV Infection in infants WHO 2009, Rapid advice: revised WHO principles and recommendations on infant feeding in the context
of HIV WHO 2010, Priority Interventions — HIV / AIDS prevention,
treatment and care in the health sector WHO 2010, Guidelines on HIV and infant feeding: Principles and recomendations for infant feeding in the context
of HIV and a summary
of evidence WHO 2010, Annexure 7b to Guidelines on HIV and infant feeding.
Meta - analyses
of studies evaluating these
programs show positive
effects on the competence, efficacy and psychological health
of the parents, as well as on the behaviour
of the children.49, 50 A recent implementation study
of a strategy for parenting and family support showed that families in the
treatment group had far fewer cases
of substantiated child maltreatment, abuse injuries and out -
of - home placements.51
«A significant body
of research has resulted in a shift from thinking
of placebos as just «dummy»
treatments to recognizing that placebo
effects encompass numerous aspects
of the health care experience and are central to medicine and patient care,» said the article's coauthor Ted Kaptchuk, Director
of the
Program in Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor
of Medicine at Harvard Medical School.
U.S. Health & Human Services Secretary Sylvia Burwell last year proposed a response, calling for a
program to change doctors» opioid prescribing practices, to expand the use
of naloxone, a drug used to reverse the
effects of an opioid overdoses, and increase patient access to medication assisted
treatments for opioid use disorders.
Instead, researchers told the European Breast Cancer Conference that their findings suggest that extending screening
programs to older women results in a large proportion
of women being over-treated, and at risk from the harmful
effects of such
treatment, because these women were more likely to die from other causes than from any tumors detected in the early stages
of growth.
The Decision Counseling
Program © developed by Dr. Myers and colleagues differs from previous decision aids in that a nurse educator uses the program not only to provide information about options, but also to identify and weigh the importance of things that matter to the patient (e.g., worry about treatment side effects, concern about developing aggressive c
Program © developed by Dr. Myers and colleagues differs from previous decision aids in that a nurse educator uses the
program not only to provide information about options, but also to identify and weigh the importance of things that matter to the patient (e.g., worry about treatment side effects, concern about developing aggressive c
program not only to provide information about options, but also to identify and weigh the importance
of things that matter to the patient (e.g., worry about
treatment side
effects, concern about developing aggressive cancer).
Other projects include an analysis
of regional variations
of cancer
treatment in Texas, a study
of the
effect of smoking bans on hospitalization rates, and a study
of whether shared savings
programs for physicians can reduce overall patient health care expenditures.
«There's a great need in cancer patients to be able to quickly and easily assess if a particular
treatment is working in order to switch to another if it's not, thus avoiding wasted time, potential side
effects and cost,» says Kala Visvanathan, M.D., M.H.S., professor
of epidemiology at the Johns Hopkins Bloomberg School
of Public Health, professor
of oncology at the Johns Hopkins University School
of Medicine and director
of the Clinical Cancer Genetics
Program at the Johns Hopkins Kimmel Cancer Center.
The implications
of these data are that maternal
treatment with antioxidants may provide possible therapy against the
programming effects on vascular dysfunction in pregnancy complicated by fetal hypoxia, such as during placental insufficiency, preeclampsia, gestational diabetes or high altitude pregnancy.
examines long - term sequelae resulting from a diagnosis
of childhood cancer and its
treatment, and health care relating to these late
effects.This multi-study initiative is funded by a Canadian Cancer Society
program project grant, with additional funding from CCS BC and Yukon Division, and has examined long - term health
effects and educational attainment, health care utilization, and quality
of follow - up care among disease survivors.
This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic
effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism
of action, KMT2D mutations
of B - lymphoma cells promote malignant outgrowth by perturbing methylation
of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual
treatment with chidamide and decitabine enhanced the interaction
of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development
of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis
of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action
of chidamide and decitabine may interfere with the differentiation and / or viability
of PTCL - NOS through a PU.1 - dependent gene expression
program.
Research in the Leukemia
Program spans from direction
of clinical trials to basic molecular studies
of leukemia biology, immunotherapy and development
of novel agents, and to mitigating the late
effects of treatment in long - term survivors.
Replacing the chemotherapy with a safe, side -
effect - free
treatment would mean that the established
programs for immune system restoration could immediately expand to become a useful, effective
treatment for immunosenescence, the age - related failure
of the immune system.
November 5, 2015 Richard L. Landau, MD, 1916 - 2015 For more than half a century, Richard L. Landau was a demanding professor
of medicine, performing path - breaking research into the
effects of human hormones and
treatment of hormone - related diseases while building a world - renowned endocrinology
program at the University
of Chicago.
This is a 1st step on the way to vindicating the positive
effects of programs like the Blue Gym and Green Gym, as well as innovative interventions by practitioners which include outdoor exercising as part
of holistic
treatments for those experiencing depression and similar mental conditions.
Some important studies include: • Beneficial
effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men (1976) • Response
of non-insulin-dependent diabetic patients to an intensive
program of diet and exercise (1982) • Diet and exercise in the
treatment of NIDDM: The need for early emphasis (1994) • Toward improved management
of NIDDM: A randomized, controlled, pilot intervention using a low fat, vegetarian diet (1999) • The
effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity (2005) • A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes (2006) • A low - fat vegan diet and a conventional diabetes diet in the
treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial (2009) • Vegetarian diet improves insulin resistance and oxidative stress markers more than conventional diet in subjects with Type 2 diabetes (2011) • Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet (2012)
Past and current research projects have explored the
effect of a diagnosis
of breast cancer on lifestyle and mental health and adherence to lifestyle - based (i.e. nutrition and exercise) and drug therapy
treatment programs.
1935
Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses
of insulin in diabetes mellitus 1958
Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial
effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977
Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982 Response
of non-insulin-dependent diabetic patients to an intensive
program of diet and exercise 1983 Long - term use
of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the
treatment of NIDDM patients 1994 Diet and exercise in the
treatment of NIDDM: the need for early emphasis 1999 Toward improved management
of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The
effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006
Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the
treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial
If one's purpose is to evaluate the
effects of a specific public policy, such as the District
of Columbia Opportunity Scholarship
Program (OSP), then the comparison
of the average outcomes
of the
treatment and control groups, regardless
of what proportion attended which types
of school, is most appropriate.
Specifically, he will work with the PI and core project staff to develop an analysis plan, direct the evaluation
of the efficacy
of the Core Knowledge Language Arts Listening and Learning Read Aloud
Program, articulate the fully specified multi-level models used to estimate
treatment impacts on child - level vocabulary, listening comprehension and domain knowledge outcomes, and guide the secondary analyses that examine whether the quality
of read alouds mediate
treatment effects on child outcomes and the baseline, child - level moderators
of treatment effects.
There have been ten analyses
of random - assignment voucher
program experiments (random - assignment being the gold - standard
of testing
treatment effects).
Researchers often summarize the impact
of programs and practices in terms
of an
effect size that measures the difference between the
treatment and control groups.
Assessing
program effects in the presence
of treatment - baseline interactions: a latent curve approach.
Correlation across HS
programs of effect of treatment on child cognitive scores (xaxis) and
effect of treatment on parent involvement (y - axis)
In
effect, the
treatment group consists
of only those students who complete a year
of preschool, and we would expect their scores to be higher (adjusting for age) than a control group that includes everyone who starts the pre-K
program.
The guidelines that are based on understanding dementia and
effects of music therapy are commonly used to design hypothetical
programs in the
treatment of Alzheimer and dementia Continue reading
In this
program, you will acquire knowledge about mood disorders, causes, symptoms and
treatment options, fostering positive prevention strategies,
treatment and recovery strategies for depression, anxiety, addiction and stress, reducing stigmatizing behaviours, attitudes and
effects, and offering support and resources for recovery and the maintenance
of wellness.
This
program provides knowledge about mood disorders, causes, symptoms and
treatment options, fostering positive prevention strategies,
treatment and recovery strategies for depression, anxiety, addiction and stress, reducing stigmatizing behaviours, attitudes and
effects, and offering support and resources for recovery and the maintenance
of wellness.
Effects were more consistent on physical abuse, however, with mothers in the
treatment group reporting fewer instances
of very serious physical abuse at one year and fewer instances
of serious abuse at two years.54 In Alaska, the HFA
program was associated with less psychological aggression, but it had no
effects for neglect or severe abusive behaviors.55 Similarly, in the San Diego evaluation
of HFA, home - visited mothers reported less use
of psychological aggression at twenty - four and thirty - six months.56 Early Start also reported small
effects in terms
of lowering rates
of severe physical abuse.57
As a family therapist and former clinical director
of adolescent
treatment programs, her concern for the adverse
effects of stress on the social and emotional development
of teens led to pioneering work in the area
of self - compassion for teens.
Participants were drawn from a larger study examining (i) the
effects of trauma on children over time and (ii) the efficacy
of the SAFE Homes intervention, a DCF
program in which children who have been removed from their parents» care are placed temporarily in state - run facilities rather than immediate foster care to facilitate assessment and
treatment planning.
In the Infant Health and Development
program, mothers in the intervention group engaged in higher - quality interactions with their infants, though the
effects were small.82 In New Zealand, Early Start documented higher positive parenting attitudes, a greater prevalence
of nonpunitive attitudes, and more favorable overall parenting scores for families in the
treatment group.83 In Queensland, mothers in the intervention group were rated as significantly higher in emotional and verbal responsivity.84
Although most outcomes were reviewed at
program completion to observe the
effects of a high - intensity comprehensive
treatment program for low - birth - weight infants, 39 certain outcomes were examined after the first year and provide a test
of the home - visiting component on its own.40
Finally, Stahmer and Gist27 examined the
effects of a parent education support group with a parent education
program that focused on pivotal response training, a
treatment program designed to enhance core skill areas in autism by using naturalistic interactions.
Indeed, the difference in surveillance between the
treatment and control groups probably explains why so few home - visiting
programs have measurable
effects on rates
of abuse and neglect.
One evaluation conducted in Queensland, Australia, reported moderate reductions in depressive symptoms for mothers in the intervention group at the six - week follow - up.89 A subsequent follow - up, however, suggested that these benefits were not long lasting, as the depression
effects had diminished by one year.90 Similarly, Healthy Families San Diego identified reductions in depression symptoms among
program mothers during the first two years, but these
effects, too, had diminished by year three.91 In Healthy Families New York, mothers at one site (that was supervised by a clinical psychologist) had lower rates
of depression at one year (23 percent
treatment vs. 38 percent controls).92 The Infant Health and Development
program also demonstrated decreases in depressive symptoms after one year
of home visiting, as well as at the conclusion
of the
program at three years.93 Among Early Head Start families, maternal depressive symptoms remained stable for the
program group during the study and immediately after it ended, but decreased just before their children entered kindergarten.94 No
program effects were found for maternal depression in the Nurse - Family Partnership, Hawaii Healthy Start, Healthy Families Alaska, or Early Start
programs.
Indeed, Jay Belsky incorporated all
of these risk factors into his process model
of parenting, 11 and data from multiple studies support links to child well - being.12 In an experiment on the effectiveness
of a
program for low - birth - weight infants, Lawrence Berger and Jeanne Brooks - Gunn examined the relative
effect of both socioeconomic status and parenting on child abuse and neglect (as measured by ratings
of health providers who saw children in the
treatment and control groups six times over the first three years
of life, not by review
of administrative data) and found that both factors contributed significantly and uniquely to the likelihood that a family was perceived to engage in some form
of child maltreatment.13 The link between parenting behaviors and child maltreatment suggests that interventions that promote positive parenting behaviors would also contribute to lower rates
of child maltreatment among families served.
Of those that examined immunizations (NFP - Memphis, HFA, HSP, EHS, Queensland, and Early Start), only EHS identified a significant program effect on immunizations, though the size of the effect was quite small and applied to the comparison of the entire treatment group to controls, not specifically to those families who had received home visits.70 The one - year follow - up of the Queensland program also suggested a trend in favor of the intervention group's having higher levels of vaccinations than the control group.
Of those that examined immunizations (NFP - Memphis, HFA, HSP, EHS, Queensland, and Early Start), only EHS identified a significant
program effect on immunizations, though the size
of the effect was quite small and applied to the comparison of the entire treatment group to controls, not specifically to those families who had received home visits.70 The one - year follow - up of the Queensland program also suggested a trend in favor of the intervention group's having higher levels of vaccinations than the control group.
of the
effect was quite small and applied to the comparison
of the entire treatment group to controls, not specifically to those families who had received home visits.70 The one - year follow - up of the Queensland program also suggested a trend in favor of the intervention group's having higher levels of vaccinations than the control group.
of the entire
treatment group to controls, not specifically to those families who had received home visits.70 The one - year follow - up
of the Queensland program also suggested a trend in favor of the intervention group's having higher levels of vaccinations than the control group.
of the Queensland
program also suggested a trend in favor
of the intervention group's having higher levels of vaccinations than the control group.
of the intervention group's having higher levels
of vaccinations than the control group.
of vaccinations than the control group.71
However, for both child abuse and parent stress, the average
effect sizes were not different from zero, suggesting a lack
of evidence for
effects in these areas.108 Earlier meta - analytic reviews have also noted the lack
of sizable
effects in preventing child maltreatment — again citing the different intensity
of surveillance
of families in the
treatment versus control groups as an explanation (though the authors did report that home visiting was associated with an approximately 25 percent reduction in the rate
of childhood injuries).109 Another review focusing on the quality
of the home environment also found evidence for a significant overall
effect of home - visiting
programs.110 More recently, Harriet MacMillan and colleagues published a review
of interventions to prevent child maltreatment, and identified the Nurse - Family Partnership and Early Start
programs as the most effective with regard to preventing maltreatment and childhood injuries.
The
program of prenatal and infancy home visiting by nurses, tested with a primarily white sample, produced a 48 percent
treatment - control difference in the overall rates
of substantiated rates
of child abuse and neglect (irrespective
of risk) and an 80 percent difference for families in which the mothers were low - income and unmarried at registration.21 Corresponding rates
of child maltreatment were too low to serve as a viable outcome in a subsequent trial
of the
program in a large sample
of urban African - Americans, 20 but
program effects on children's health - care encounters for serious injuries and ingestions at child age 2 and reductions in childhood mortality from preventable causes at child age 9 were consistent with the prevention
of abuse and neglect.20, 22
Where
program effects were moderated by the child's sex in a coherent way, we have noted this in the presentation
of the findings, in which case the model includes SES as a covariate rather than a classification factor and includes all interactions among
treatment, marital status, and sex.
Behavioral assessment
of psychostimulant
effects on ADD children in a summer day
treatment program.
Identifies seven studies and applies meta - analysis technique to examine, compare, and synthesize the
effects of caregivers» engagement and retention in substance abuse
treatment programs.
Meta - Analysis
of Substance Abuse
Treatment Intervention on Child Welfare Outcomes (PDF - 1,002 KB) Zhang, Huang, & Liu (2014) Identifies seven studies and applies meta - analysis technique to examine, compare, and synthesize the effects of caregivers» engagement and retention in substance abuse treatment
Treatment Intervention on Child Welfare Outcomes (PDF - 1,002 KB) Zhang, Huang, & Liu (2014) Identifies seven studies and applies meta - analysis technique to examine, compare, and synthesize the
effects of caregivers» engagement and retention in substance abuse
treatment treatment programs.
Preventive interventions often find that
treatment effects for certain outcomes vary across subgroups
of study participants.11, 12 In this study, we examine how domestic violence limits the effectiveness
of the home - visitation
program in preventing maltreatment.
In addition, many
of the early intervention
programs that have been shown to have positive
treatment effects are resource intensive and target high - risk families, on the basis
of socioeconomic status, childhood disabilities, parental substance use, or child maltreatment.1
Evaluations
of sustained
treatment effects for other, more - intensive, early childhood interventions have yielded mixed results, with variation being attributed to unevenness in both
program quality and evaluation rigor.10, 11 Less - intensive interventions, such as the Comprehensive Child Development Program, have reported no effect during or after the intervention.12 Intensive interventions with short - term effects seem to be more likely to demonstrate sustained benefits for children's cognitive and social development and parenting behav
program quality and evaluation rigor.10, 11 Less - intensive interventions, such as the Comprehensive Child Development
Program, have reported no effect during or after the intervention.12 Intensive interventions with short - term effects seem to be more likely to demonstrate sustained benefits for children's cognitive and social development and parenting behav
Program, have reported no
effect during or after the intervention.12 Intensive interventions with short - term
effects seem to be more likely to demonstrate sustained benefits for children's cognitive and social development and parenting behaviors.11
The absence
of program effect with the official arrest data may be explained by a significant, 9-fold higher rate
of official arrest records prior to randomization (0.44 vs 0.05) found for
treatment group 4 mothers who were unmarried and
of low SES and whose children remained in Chemung County compared with their
treatment group 1 and 2 counterparts.