Sentences with phrase «effects on atherosclerosis»

Not exact matches

«Trans - fatty acids increase LDL cholesterol [our «bad» cholesterol], and they don't have much of an effect on HDL [our «good» cholesterol],» contributing to cardiovascular disease risk, says Alice Lichtenstein, a nutritional biochemist at Tufts University in Boston, who published a review on the topic in Current Atherosclerosis Reports in June 2014.

The study constituted part of the extensive, population - based DR's EXTRA study, which was a four - year randomised and controlled intervention study analysing the effects of exercise and nutrition on endothelial function, atherosclerosis and cognition.

Professor Taborsky said: «This is the first randomised trial comparing the effects of red and white wine on markers of atherosclerosis in people at mild to moderate risk of CVD.

The IVV study is the first long - term, prospective randomised trial comparing the effect of red and white wine on markers of atherosclerosis.

Heart specialists have used the test, known as carotid intima - media thickness, or CIMT, for more than a decade in large research studies to monitor the effects of exercise, diet or medications on the progression of atherosclerosis.

To study the effects of hyperinsulinemia on atherosclerosis, Rask - Madsen and his colleagues created mice with fewer insulin receptors in every tissue of the body and compared them to mice with intact insulin receptors.

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.

In an investigation of the effects of bergamot on atherosclerosis in carotid arteries in a clinical setting, just six months of therapy reduced measures of plaque in these important arteries compared to placebo.

Dr. McCully's research over the past 40 years on the pathogenesis of atherosclerosis has shown the role of homocysteine in free radical damage and the protective effect of vitamins B6, B12 and folate.

A Chinese research team published in the journal Atherosclerosis examined the effect of CoQ10 on the delicate endothelial lining of the coronary arteries.

Here we summarize the results of the long - term TEAAM (Testosterone's Effects on Atherosclerosis Progression in Aging Men) study, which also investigated effects of testosterone treatment on muscle performance, physical function, and lean body mass.

«The positive ecological correlations between national intakes of total fat and saturated fatty acids and cardiovascular mortality found in earlier studies were absent or negative in the larger, more recent studies,» the authors wrote, concluding that «the harmful effect of dietary saturated fatty acids and the protective effect of dietary polyunsaturated fatty acids on atherosclerosis and cardiovascular disease are questioned.»

Medical Hypotheses: «Anti-inflammatory effect is an important property of niacin on atherosclerosis beyond its lipid - altering effects.»

The Journal of Molecular Medicine also studied the effect of red wine on atherosclerosis and yielded some interesting results.

the effect of red wine on atherosclerosis and yielded some interesting results.

Published in Atherosclerosis Journal and using the Cochrane's review methodology, the authors of the analysis settled on using 52 studies using a variety of search terms, primarily focusing on cardiovascular and endothelial effects.

Although much of the early work on the link between diet and CVD focused primarily on dietary fats and their effect on total and LDL - cholesterol concentrations, there are many other dietary elements that can operate synergistically to promote atherosclerosis.