Sentences with phrase «effects on blood cells»

Periodic blood testing is required to monitor liver function and for any toxic effects on blood cells

Not exact matches

In diseases such as malaria and sickle cell disease, red blood cells break down, with harmful effects on the rest of the body — particularly the lining of small blood vessels.

And if you don't deny it, then why discredit the fact that food, the very substance that all humans need in order to keep organs functioning, blood pumping, toxins dispelling, cells forming, could be causing severe effects on our health if the wrong foods are eaten?

Studies have shown that chlorophyll found in food or small purified amounts of chlorophyll have a favorable effect on red blood cell formation in the bone marrow.

However, rEPO actually the opposite effect on blood: blood gets thicker because there are more red cells.

Once the baby begins to mature and the red blood cell amounts diminish, the jaundice will subside with no lasting effects on the baby.

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

The boosted genes had three main effects: improving cellular energy efficiency; upping insulin production, which improves control of blood sugar; and preventing the breakdown of caps on chromosomes that help prevent cells wearing out and ageing.

Based on what is already known about fostamatinib toxicity, Shih says that patients using a combination of fostamatinib and paclitaxel may experience side effects that include low white blood cell counts, nausea, vomiting and diarrhea.

The virus does this because, unlike most microbes, Zika can pass from blood into the brain, where it infects and kills stem cells, having severe effects on developing brains.

The study, recently published in Cell Metabolism, also found that beige fat, unlike the better - known white and brown fat, has interesting anti-diabetic effects on blood sugar metabolism that seem independent of temperature regulation.

Using a surgical technique called parabiosis to join the circulatory system of a young mouse with that of an old one, the researchers studied the effects of young blood on elderly cells, and vice versa.

Therefore, they must explore the effects of deactivating it on the body's ability to fight infections and other diseases — as hampering the gene's effects only in red blood cells would be difficult.

Most importantly, the doxorubicin - decorated diamonds had no effect on white blood cell count, an indicator of immune system activation that's often the deciding factor in whether a patient can continue chemotherapy.

In this study, we found that chloroquine not only has an effect on the growth of the cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.

The researchers examined the in vitro effects of insulin - like growth factor 1 (IGF - 1) on lithium sensitivity in blood cell lines of both lithium - responsive and non-responsive bipolar patients.

The toxicity of chokeberry extract on normal blood vessel lining cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in cancer cell growth.

Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging - independent, mechanisms.»

«Natural resistance to malaria linked to variation in human red blood cell receptors: First study to identify protective effect of glycophorin gene rearrangements on malaria.»

In her most recent paper, Ennis describes how her team looked at the effects of ultra-dilute solutions of histamine on human white blood cells involved in inflammation.

«Numerical simulations of tensile tests of red blood cells: The researchers investigate the effects of the hold position of the red blood cells on strain field during tensile testing using numerical simulations.»

ASH is alarmed about the opioid crisis; however, it is concerned about potential adverse effects that policy changes could have on the administration of necessary and appropriate pain medicine for patients with hematologic conditions such as sickle cell disease (SCD), blood cancers, and other bleeding disorders.

In cultured human cells and in rabbits with implanted stents, Finn and colleagues showed that metformin augmented the effect of mTOR inhibitors on regrowth of the blood vessel lining.

Concussion: Examining the Effect of Neuronal Oxidative Stress on the Pathophysiology of Brain and Blood Brain Barrier Cells.

Under the mentorship of Micheala Aldred, PhD, Associate Staff of the Genomic Medicine Institute, Dr. Drake has studied the effect of experimental drugs on cultured lung or blood cells isolated from PAH patients.

By the end of the two years, we will have worked out how good this experimental approach is at preventing blood vessel growth, and also any possible side effects on healthy eye cells.

«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.

The cell assays are based on blood samples or tissue biopsies from these patients, and readouts are either specific, such as antibody production or the production of proinflammatory cytokines, or wider, such as proteomic effects of the probes.

We came across a compound that had been isolated from a plant species and shown to have effects on blocking the growth of blood vessel cells, both in the culture dish and also in animal models.

We found that it is very selective and potent at stopping the growth of blood vessel cells without having negative effects on the growth of other cell types from the eye and elsewhere in the body.

This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

The scientists then isolated immune cells from human blood and studied the effects GABA had on these cells.

Our goal is to create a microfluidic 3D cell culture system representing a «placenta - on - a-chip» in order to mimic the nutrient / waste transfer between maternal blood and fetal blood that occurs in the cotyledon section of the placenta, and to test and observe the effects of ethanol within the maternal bloodstream and compare it to a similar in vivo situation.

Garlic is said to have detoxifying effects on the body; cleansing the blood, eliminating age - accelerating toxins stored in the cells and clearing the skin.

Furthermore, saturated fat has been shown to have numerous positive effects on health, such as improving liver health by encouraging the liver cells to get rid of their fat cells, improving the immune system's response by helping white blood cells to recognize and destroy invaders more effectively, enabling the absorption of fat - soluble vitamins by acting as their carriers, as well as improving hormonal activity by providing the building blocks for a variety of hormones that are essential to human health.

It also appeared to lower levels of a marker of inflammation found in the blood of people with Alzheimer's (called high - sensitivity c - reactive protein)-- although it had no effect on other biomarkers of cell damage or inflammation.

Check immune markers such as your white blood cell count and high sensitivity c - reactive protein, as well as cholesterol, to see what impact it has on these markers — for some people the positive effects are astounding.

Insulin allows blood sugar to enter the cells to supply the body with energy, but continually choosing foods — and drinks — high in sugar, combined with being overweight, has a strong effect on the delicate balance between blood sugar and insulin levels.

Depending on the formulation, treatment can cause skin irritation, breast enlargement and tenderness, sleep apnea, acne, reduced sperm count, increased red blood cell count, and other side effects.

Here's why: When you eat sugars (good and bad ones), your body produces insulin to regulate the effect on your blood, metabolism, and cell growth.

Histamine four has an effect on the intestines, the spleen the colon, white blood cells and the inflammatory response.

Ashwaganda — This herb helps to correct cortisol levels by either boosting energy by day or calming the individual at night, and also stabilizing blood sugar, improving memory and reducing the effects on stress on brain cells (Pratte et al., 2014).

This effect is achieved by the lowering of blood pressure in cases of diabetic patients, decreasing oxidative stress on the sensitive sperm cells and therefore minimising damage to their DNA cargo4.

A group of scientists recently published a paper describing what happened when they ordered some dioxin from Dow Chemical, grabbed some DDT while they were at it, and dripped the chemicals on some human white blood cells, with and without a variety of phytonutrients, to see if they could have a protective effect.

Another consequence of low aldosterone is electrolyte imbalance and cell dehydration, which both have negative effects on almost all physiological reactions in the body: aside from salt cravings, low blood pressure and light - headedness, patients with adrenal fatigue often experience an irregular heart beat, lethargy, muscle weakness, and increased thirst.

Consuming 0.5 ml peppermint oil in a drink for 10 consecutive days was found to improve body performance since it increases respiratory system efficiency through increasing capacity of lungs, oxygen supply to muscle cells, and its inhibitory effect on blood pressure.

These foods increase blood flow to the brain and protect brain cells from oxidative stress and also decrease the effects of age - related conditions like dementia and Alzheimer's (study on blueberries and Alzheimer).

• widespread effects on circulation, muscles and sugar metabolism • raised heart rate • increased heart output • increased rate and depth of breathing • increased metabolic rate • increased force of muscular contraction • delayed muscular fatigue • reduced blood flow to bladder (muscular walls relax and sphincters contract) • reduced blood flow to intestines • increased blood pressure • increased sugar (glucose) in the blood • increased break - down of glucose for energy *, especially in muscle cells • increased free fatty acids in the blood * • more oxidation of fatty acids to produce energy * • more ATP (the cells» primary energy compound) produced * • blood vessels constrict

Professor Oliver like many experts, believes that the very lowering of blood cholesterol may actually be dangerous: «Very little is known about the long - term effects of lowering cholesterol concentrations on the composition of cell membrane».