Sentences with phrase «effects on brain cells»

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

Fang's team decided to test xanthohumol's effects on brain cells.

The automated method could also be used to easily test the effects on brain cells of a range of molecules and see which might be drug candidates.

They found that the TLR3 inhibitor significantly tempered Zika virus» severe effects on brain cell health and organoid size, underscoring TLR3's role linking infection and brain damage.

IGF - 1 has a similar protective effect on brain cells.

Not exact matches

You have probably heard a number of rumors about the effects of technology on your health; that having a cell phone next to your head can cause brain cancer, for example, or that pregnant women shouldn't stand near a microwave that is running because it may harm the fetus.

Markram's model will electronically mirror the real brain's biological behaviors, imitating mathematically the interactions among individual neurons and the effects of neurotransmitters on those cells.

The virus does this because, unlike most microbes, Zika can pass from blood into the brain, where it infects and kills stem cells, having severe effects on developing brains.

Previous research had shown that nicotine seems to have conflicting effects on different types of nicotinic acetylcholine receptors, proteins on the surface of brain cells that respond to nicotine and the naturally occurring neurotransmitter acetylcholine.

He examined the direct impact of the substance on neural effects using tests involving brain cells.

Morphine and its derivatives seem to exert their effects by binding to specific receptor sites on cells in the brain and the spinal cord.

As microglia are very long - lived, the scientists were keen to find out whether environmental factors change these immune cells over time and what effect this can have on brain health.

Ringer's lactate solution (Lactec) was irradiated with plasma for 3 - 5 minutes, after which it demonstrated anti-tumor effects on brain tumor cells.

This metabolic demand makes brain cells particularly vulnerable to damage from oxidative stress, in which reactive oxygen species (ROS), sometimes called free radicals, exert toxic effects on cellular components.

Nevertheless, «as time goes on, the cavitation effects from the bullet itself» are likely going to continue to kill off brain cells, Rhee noted.

«This lets us keep age - related signatures in the cells so that we can more easily study the effects of aging on the brain,» says Rusty Gage, a professor in the Salk Institute's Laboratory of Genetics and senior author of the paper, published October 8, 2015 in Cell Stem Cell.

To study brain cell's operation and test the effect of medication on individual cells, the conventional Petri dish with flat electrodes is not sufficient.

The researchers also found that activating these brain cells while the mice were awake had no effect on wakefulness, but did make them eat more.

They focused this effect on the hypocretin neurons, which are brain cells in the lateral hypothalamus.

After concluding that increased stem cell production in a certain area of the brain had a positive effect on behavioral deficits of Alzheimer's, Prof. Offen has moved to research into the area of the brain that controls memory.

Previous studies have shown that a special type of cortical interneurons, called basket cells, exerts a strongly inhibitory effect on brain circuits.

«More importantly, a retrovirus can infect only dividing cells such as reactive glial cells, but it does not affect neurons, which makes it ideal for therapeutic use with minimal side effect on normal brain functions.»

Thus, this study offers real hope for combating the bad effects of HIV / AIDS on stem cells in the brain.»

Concussion: Examining the Effect of Neuronal Oxidative Stress on the Pathophysiology of Brain and Blood Brain Barrier Cells.

Immediate and lasting effects of chronic daily methamphetamine exposure on activation of cells in hypothalamic - pituitary - adrenal axis - associated brain regions.

Understanding the effects that variations of these genes have on brain - cell function could lead to explanations of how they contribute to the condition and how it might be better prevented or treated.

The team used genetically engineered mice to study the effects of different human apoE variants on the maturation of neural stem cells or progenitor cells, from which new neurons develop in the adult brain.

«This new, well - conducted study published in the respected journal Nature Medicine investigated the effects of low doses of one of the major active ingredient in cannabis, delta - 9 tetrahydrocannabinol (THC), on memory function and brain cells in mice.

But all of this is about the effects of an agricultural pesticide on the brain, which immediately presses the question: does it really tell us anything about how senescent cells contribute to «regular» PD, driven by the intrinsic aging processes responsible for the great majority of cases of PD?

«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.

Glial cell line - derived neurotrophic factor (GDNF) was selected based on clear evidence that it increases neuronal sprouting, prevents cell death [20], [21] and has neuroprotective effects in the brain [11], [22]--[24], spinal cord [12] and retina [25]--[30], and because receptors for GDNF are expressed within mature retina [26], [31]--[34].

The Zika virus is known to negatively impact the growth of fetal brains and a group of researchers publishing in the journal Cell Stem Cell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatCell Stem Cell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatCell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatcell death and reduced proliferation.

Additional exploratory objectives include assessing the impact that each compound has on the toxic mutant protein known to cause loss of brain cells in HD, as well as evaluating potential clinical effects and impact on brain atrophy as measured by magnetic resonance imaging (MRI).

The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.

Ashwaganda — This herb helps to correct cortisol levels by either boosting energy by day or calming the individual at night, and also stabilizing blood sugar, improving memory and reducing the effects on stress on brain cells (Pratte et al., 2014).

In this episode Rhonda talks about how heat stress from using the sauna makes the body more resilient to the stresses of aging, possible reasons why one study associated sauna use with up to a 40 % lower all - cause mortality as well as a 50 % lower cardiovascular disease related mortality, how it enhances athletic endurance, staves off muscle atrophy, improves regrowth of muscle after disuse, and some of the profound effects on the brain, including the growth of new brain cells, improvement in focus, learning, and memory, and even potentially ameliorating depression and anxiety.

The effect of EMF on your nerves, cells, heart and brain is proven and substantial — which you'll learn about later in this book.

In other words, increasing plasma GSH by supplementing with whey protein may not necessarily have the desired effect on the appropriate brain cells and tissues.

These foods increase blood flow to the brain and protect brain cells from oxidative stress and also decrease the effects of age - related conditions like dementia and Alzheimer's (study on blueberries and Alzheimer).

You probably already know some of the harmful health effects of these foods, but long term effects on your brain are yet another... Trans fats — strongly inflammatory in your entire body including damage to cell membranes throughout your body.

Recent research on the effect of aromatic turmerone, a turmeric extract, shows that the plant extract may help regenerate damaged brain cells after things like a stroke.

Nearly every cell in your body was designed to use glucose for energy — especially your brain cells — but fructose breaks down into a variety of toxins that can have devastating effects on your health.

Ketones not only provide a high quality source of energy for the brain but trigger the activation of special proteins that function in brain cell maintenance, repair, and growth, thus providing a therapeutic effect on the brain.

Dietary fibre modifications that are low in fat and glucose reduce the risk for AD by not only effecting cell membranes and nutrient sensing G coupled receptors but also by regulating number of nuclear receptors such as histone deacetylases (HDAC) and peroxisome proliferator activated receptors (PPAR) that control glucose, fatty acids and cholesterol and have significant effects on the brain cholesterol homeostasis and amyloidosis.

But, what about the consideration (even with moderate alcohol consumption) of its effect on liver health and brain cells?

Titled, «Aromatic - turmerone induces neural stem cell proliferation in vitro and in vivo,» German researchers evaluated the effects of this turmeric - derived compound on neural stem cells (NSCs)-- the subgroup of brain cells capable of continuous self - renewal required for brain repair.

I can assure you that so far as my own experiences have shown me, and some of my instrumentation has been part of everything from measuring re-entry temperatures on the Space Shuttle to research studying the effects of small temperature changes on types of brain cells, that I've rarely found anything that made me question the theories I was taught.

Effects on Brain Development from Terbutaline, Pesticides Both chemicals independently caused brain injuries not seen in the control rats, including the loss of brain cells and the nerve cell projections critical to communication among neurons; and the effects persisted into adultBrain Development from Terbutaline, Pesticides Both chemicals independently caused brain injuries not seen in the control rats, including the loss of brain cells and the nerve cell projections critical to communication among neurons; and the effects persisted into adultbrain injuries not seen in the control rats, including the loss of brain cells and the nerve cell projections critical to communication among neurons; and the effects persisted into adultbrain cells and the nerve cell projections critical to communication among neurons; and the effects persisted into adulthood.

[2] An August 2016 study looking at the effect of Zika infection on the adult brain suggests that adult brain cells responsible for replacing lost or damaged neurons throughout adulthood, cells that are likely critical to learning and memory, may be vulnerable to infection.

Animals exposed to enriched environments high in stimulation have been shown to display increased hippocampal cell proliferation and neurogenesis compared with those reared in relative deprivation.7 Poverty represents a form of human deprivation that may parallel this animal model, raising the question of whether low levels of stimulation and relative psychosocial neglect associated with poverty have a similar negative effect on human brain development.