Sentences with phrase «effects on human cells»

Anti-oxidants and phyto - nutrients are known to have protective effects on human cells, retard or reverse growth of cancer cells, and prolong healthy life.

Researchers have long sought to understand how it is that using a chemical designed to specifically target bacteria could actually bring about such damaging effects on human cells.

The science behind this has been little understood until now, and possible effects on human cells were not previously investigated.

Since bacterial cell walls and human cell walls are very different, penicillin has a big effect on certain species of bacteria but no effect on human cells.

They reasoned that the same three genes could have the same effect on human cells.

Not exact matches

With proper repetitions, negative controls and statistical analyses, the effects of carrageenan exposure on human cells can be better understood.

And if you don't deny it, then why discredit the fact that food, the very substance that all humans need in order to keep organs functioning, blood pumping, toxins dispelling, cells forming, could be causing severe effects on our health if the wrong foods are eaten?

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

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Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

While testing the effect of many normal, non-cancerous, human cells on the sensitivity of cancer cells to chemotherapy, they found a specific sample of normal human skin cells that rendered pancreatic cancer cells resistant to gemcitabine.

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.

«It's true that many laboratory studies have examined the effect of nanomaterials on human and animal cells.

First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests using human lung cells.

With a view to clinical studies (tests on humans) it is important to note that the effects on the tumor vasculature were even observed at chloroquine concentrations that had little effect on autophagy in the cancer cells.

In an accompanying paper, MacKinnon's team notes that scorpion toxin — a potent potassium channel inhibitor — has the same effect on pores in S. lividans and those of the fruit fly Drosophila, whose nuclei are organized similar to those of human cells.

They then examined genetic variants throughout the human genome for their effects on gene expression in these two representative populations of immune cells.

The IBS research team (Center for Genome Engineering) has successfully confirmed that CRISPR - Cas9 has accurate on - target effects in human cells, through joint research with the Seoul National University College of Medicine and ToolGen, Inc..

In the lab, the antibiotics had no harmful effect on normal cells, and since they are already approved for use in humans, trials of new treatments should be simpler than with new drugs — saving time and money.

By now, European astronauts had hoped to be established in their space laboratory called Columbus, where they would be melting and solidifying conductive metals, studying microgravity effects on single - celled organisms, investigating human balance disorders, and carrying out dozens of other experiments.

«We hypothesize that older humans might be especially susceptible to the effects of sleep deprivation on the disruption of glucose homeostasis via cell stress.»

In this study, the researchers tested the effects of Olaparib on the tumors formed by human breast cancer cells injected into mice.

«With the help of animal biologists, we found that chem7 had no effect on budding yeasts and human cells, which indicates that chem7 does not inhibit the cell division of animal cells.»

Sood and his team first studied the effects of stress hormones on human ovarian cancer cell anoikis in culture.

«Natural resistance to malaria linked to variation in human red blood cell receptors: First study to identify protective effect of glycophorin gene rearrangements on malaria.»

Prins investigated the effect of BPA on human cells by implanting human prostate stem cells taken from deceased young - adult men into mice.

The Simon lab is now working on testing the effects of the chimera on human liver cells and in mouse livers, to further elucidate its role in the disease.

Cell - based biosensors can simulate the effect of various substances, such as drugs, on the human body in the laboratory.

The investigators studied application of various doses of a common PBDE flame retardant on human adrenal cells in culture dishes and compared the effects with those of only the vehicle, the inactive substance used to deliver the chemical.

«The introduction of mitochondria into damaged cells has beneficial effects on the health of cells and, in the long term, we believe that mesenchymal stem cells could even be engineered to create more effective therapies for lung disease in humans.»

Since the thyroid absorbs nearly all of the iodine in the human body, radioactive iodine given to a patient will concentrate in thyroid cancer cells, killing them with little effect on the rest of the body.

They then used human stem cells derived from bone marrow that would normally become bone cells to test the effects of the nanoparticles on stem cell proliferation and differentiation.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.

In her most recent paper, Ennis describes how her team looked at the effects of ultra-dilute solutions of histamine on human white blood cells involved in inflammation.

This adds the possibility of in vivo experiments on therapeutic effects using human - derived cells in the mouse embryo.

«While genetic modification of crops can introduce new beneficial traits into existing crops, the resulting products need to be tested for long - term health effects before making assumptions about their impact on human health,» said senior investigator Frances Sladek, a professor of cell biology and neuroscience at UC Riverside.

It is a continuation of previous research, published in 2011, that focused on the effect of decitabine on glioblastoma human cell cultures.

Beilhack and colleagues found that a slightly modified version of STAR2 has a similar effect on human T reg cells, suggesting that the approach could also prevent GvHD in leukemia and lymphoma patients after bone marrow or hematopoietic stem cell transplants.

To determine whether the reactivation of methylation - silenced genes by EGCG is a general phenomenon that also occurs in other cell lines, we studied the effects of EGCG treatment on the methylation status and mRNA levels of p16INK4a or RARβ in three other human cancer cell lines (Fig. 3C) ⇓.

This thesis primarily investigates the effects of mechanical cyclic stretching, a 5 % low oxygen atmosphere and the Rho - kinase inhibitor, Y - 27632, on protein responses in chondrocytic human chondrosarcoma (HCS - 2 / 8) cells.

Recombinant human granulocyte colony - stimulating factor: effects on normal and leukemic myeloid cells.

Effect of Saturated Stearic Acid on MAP Kinase and ER Stress Signaling Pathways during Apoptosis Induction in Human Pancreatic ß - Cells Is Inhibited by Unsaturated Oleic Acid.

By combining SNP - targeting allele - specific silencing and gain - of - function approaches, we showed that a 46 - glutamine expansion in human HTT was sufficient for a dominant - negative effect on spindle orientation and changes in the distribution within the spindle pole and the cell cortex of dynein, p150Glued and NuMA in neural cells.

In cultured human cells and in rabbits with implanted stents, Finn and colleagues showed that metformin augmented the effect of mTOR inhibitors on regrowth of the blood vessel lining.

Palmitate and oleate have distinct effects on the inflammatory phenotype of human endothelial cells.

Investigating the effects of preinduction on human adipose - derived precursor cells in an athymic rat model.

Multiple effects of a novel epothilone analog on cellular processes and signaling pathways regulated by Rac1 GTPase in the human breast cancer cells.

Recently, his lab used induced pluripotent stem (iPS) cells — adult cells made to act like embryonic stem cells — made from skin cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of human neurons.

Effect of Local Anesthetics on Human Mesenchymal Stromal Cell Secretion.