We find strong and consistent evidence of positive contributions of teacher assistants, an understudied staffing category, with larger
effects on outcomes for minority students than for white students.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential
for additional forward losses
on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the
effect on aircraft demand and build rates of changing customer preferences
for business aircraft, including the
effect of global economic conditions
on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the
effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals
for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact
on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact
on the demand
for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns
on pension plan assets and the impact of future discount rate changes
on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price
for our announced acquisition of Asco
on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the
effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the
effect of changes in tax law, such as the
effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted
on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the
effect of such changes; 21) any reduction in our credit ratings; 22) our dependence
on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments
on defense; 25) the possibility that our cash flows and our credit facility may not be adequate
for our additional capital needs or
for payment of interest
on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the
outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions
for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
These risks and uncertainties include, among others: the unfavorable
outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings
for our products, including our clinical trial designs, conduct and methodologies and,
for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed
on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement
for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side
effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report
on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available
on the SEC's website at www.sec.gov.
Such risks, uncertainties and other factors include, without limitation: (1) the
effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities
for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the
outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the
effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the
effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU,
on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the
effect of changes in tax (including U.S. tax reform enacted
on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition
on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative
effects of the announcement or the completion of the merger
on the market price of United Technologies» and / or Rockwell Collins» common stock and / or
on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in
effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
Though the Trump White House has acknowledged that Russia meddled — while maintaining that it was not to help Trump and did not have an
effect on the election's
outcome — it has so far fallen short of making a specific statement or calling out Russia
for its aggression.
While the UK economy has already shown signs of slowing and would probably feel the greater
effect as businesses accelerate their contingency measures
for such an
outcome, the possible impact
on the EU may be significant and remains somewhat underappreciated, in our view.
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential
effects of new laws or regulations or changes in existing laws or regulations; the
outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required
for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger;
effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report
on Form 10 - K and subsequent reports
on Forms 10 - Q and 8 - K available
on the Investor Relations section of www.cigna.com as well as
on Express Scripts» most recent report
on Form 10 - K and subsequent reports
on Forms 10 - Q and 8 - K available
on the Investor Relations section of www.express-scripts.com.
This inequitable situation translates into less opportunity and social mobility
for everyone, and is having a corrosive
effect on everything from health
outcomes to social cohesion and the functioning of our democracy.
Related literature
on neighborhood
effects has found that labor market
outcomes for adults are also significantly affected by the type of neighborhoods where people reside.
The researchers also find that parental expectations, proxied by information
on whether parents have set aside savings
for their children's college expenses, have a large
effect on future labor market
outcomes.
Actual results may vary materially from those expressed or implied by forward - looking statements based
on a number of factors, including, without limitation: (1) risks related to the consummation of the Merger, including the risks that (a) the Merger may not be consummated within the anticipated time period, or at all, (b) the parties may fail to obtain shareholder approval of the Merger Agreement, (c) the parties may fail to secure the termination or expiration of any waiting period applicable under the HSR Act, (d) other conditions to the consummation of the Merger under the Merger Agreement may not be satisfied, (e) all or part of Arby's financing may not become available, and (f) the significant limitations
on remedies contained in the Merger Agreement may limit or entirely prevent BWW from specifically enforcing Arby's obligations under the Merger Agreement or recovering damages
for any breach by Arby's; (2) the
effects that any termination of the Merger Agreement may have
on BWW or its business, including the risks that (a) BWW's stock price may decline significantly if the Merger is not completed, (b) the Merger Agreement may be terminated in circumstances requiring BWW to pay Arby's a termination fee of $ 74 million, or (c) the circumstances of the termination, including the possible imposition of a 12 - month tail period during which the termination fee could be payable upon certain subsequent transactions, may have a chilling
effect on alternatives to the Merger; (3) the
effects that the announcement or pendency of the Merger may have
on BWW and its business, including the risks that as a result (a) BWW's business, operating results or stock price may suffer, (b) BWW's current plans and operations may be disrupted, (c) BWW's ability to retain or recruit key employees may be adversely affected, (d) BWW's business relationships (including, customers, franchisees and suppliers) may be adversely affected, or (e) BWW's management's or employees» attention may be diverted from other important matters; (4) the
effect of limitations that the Merger Agreement places
on BWW's ability to operate its business, return capital to shareholders or engage in alternative transactions; (5) the nature, cost and
outcome of pending and future litigation and other legal proceedings, including any such proceedings related to the Merger and instituted against BWW and others; (6) the risk that the Merger and related transactions may involve unexpected costs, liabilities or delays; (7) other economic, business, competitive, legal, regulatory, and / or tax factors; and (8) other factors described under the heading «Risk Factors» in Part I, Item 1A of BWW's Annual Report
on Form 10 - K
for the fiscal year ended December 25, 2016, as updated or supplemented by subsequent reports that BWW has filed or files with the SEC.
These so - called «broker non-votes» will be included in the calculation of the number of votes considered to be present at the meeting
for purposes of determining a quorum, but will not be considered in determining the number of votes necessary
for approval and will have no
effect on the
outcome of the vote
for Directors, the advisory vote
on executive compensation, the amendment of the Restated Certificate of Incorporation and the shareholder proposals.
to Emil Brunner (by which writing, incidentally, Americans still know him best) reflected his sense
for the possible
effect of Brunner's speaking of nature and grace»
on the
outcome of that struggle.
Unconscionable conduct (agrees with NFF that they have not provided protection and support reforms «to provide transparency in the supply chain» and recognise that «certain classes of suppliers... are predisposed to suffering from a special disadvantage...»; misuse of market power (legal framework must «level the balance of market power in negotiations...», «ensure transparency in the transmission of market prices» and «not allow
for final market risks to be borne by the primary producer» and provide «transparency of contract processes» - specifically, Canegrowers supports
effects test and a process giving ACCC greater power to «regulate anti-competitive behaviour and impose penalties», shifting «the decisions framework from the judicial system to a regulatory system» which would make it more accessible to small producers); collective bargaining (notes limits of Sugar Industry Act (Qld); authorisation and notification approval costly and limited and not a viable alternative - peak bodies should be able to «commence and progress collective bargaining with mills
on behalf of their members» and current threshold too restrictive)» competitive neutrality (mixed
outcomes - perverse
outcomes in the case of natural monopolies - suggest remove «application of competitive neutrality provisions to natural monopoly essential services»)
With decisive games coming up against Juventus and Inter, it could all depend
on the
outcomes of these two encounters and it may well have a knock -
on effect in terms of determining their budget
for the summer transfer window.
The contenders
for the title have all strengthened and not many fans would back against Man City with Pep in charge (not my choice) taking top spot with the other 3 places up
for grabs but there are a lot of permutations to take place that can and will have an
effect on the
outcome.
One thing's
for sure, it'll be interesting to see whether the
outcome of next month's Champions League tie between Man City and Liverpool has any
effect on who comes out winner of the award.
Ryan did fumble it, the defender absolutely used the ground
for the INT, Hardy fumbled his catch, and I'm sure Gabriel was held
on fourth and one, but we r too damn good to even let the zebras
effect the the
outcome of the game..
I know I'm ranting
on my own here, but it is deeply depressing that football is being degraded by actions ranging from players diving (cheating) right up to national governments using their wealth to
effect outcomes — what hope is there
for the game?
Childhood obesity can have negative
effects on health
outcomes, including putting kids at risk
for Type 2 diabetes and high blood pressure.
Holding men who use violence fully responsible
for their behaviour and its
effect on their children will provide better
outcomes for the whole family.
For those in the middle though, it can definitely help to know the pros and cons — and the fact that epidurals don't appear to have an
effect on the length or
outcome of delivery could certainly sway that choice.
There is no medical reason
for such high levels of intervention and the
effects of these interventions
on first time mothers will influence the
outcome of any future pregnancies they may have.
No responsible scientist would say «zero»
effect of breastfeeding
on intelligence because it is impossible to measure every intellectual
outcome or do it in a randomized manner
for an appropriate length of time.
We used mean difference (MD) with 95 % confidence interval (CI), employing a random -
effects model
for continuous
outcomes measured
on the same scales.
Two reviews do not report summary measures of effectiveness but suggest that parent training has a positive
effect on children's behaviour problems, parental well - being and social
outcomes [15] and a positive
effect for young children with conduct disorder [16].
Review objective: to compare the
effects of group antenatal care versus one - to - one care
on outcomes for women and their babies.
To examine whether the
effects of breastfeeding varied
for boys and girls, the analyses were extended to include tests of interactions between gender and measures of breastfeeding in their
effects on cognitive and educational
outcomes.
Thus,
for these studies there is a clear reliance
on either matching or statistical adjustment
for the
effects of other factors correlated with feeding method that may also influence child
outcomes such as maternal IQ and / or parenting style.
The
effects of breastfeeding
on children's development have important implications
for both public - health policies and
for the design of targeted early intervention strategies to improve the developmental
outcomes of children at risk as a result of biological (e.g., prematurity) or social adversity (e.g., poverty).
President Akufo - Addo has suspended with immediate
effect, the Minister
for the Upper West Region, Alhaji Sulemana Alhassan, pending the
outcome of the investigation into the unfortunate incidents that occurred at the premises of the Upper West Regional office of the National Disaster Management Organisation (NADMO), in Wa,
on Wednesday, 31st January, 2018.
The problem with predicted
outcomes of AV based
on,
for example, successive YouGov polls looking at voters preferences is that they really only tell us about short term
effects on the relative position of the big established parties.
In 2016 NLGN published All Together Now: Whole systems commissioning
for councils and the voluntary sector, which concludes that raising the scoring
for social value in the commissioning process could have a profound
effect on how local government work with its partners and
on the
outcomes it is able to deliver
for citizens.
Researchers at the Veterans Health Administration conducted a systematic review of 67 published studies to determine the effectiveness of strategies to reduce or discontinue long - term opioid therapy prescribed
for chronic pain and the
effect of dose reduction or discontinuation
on important patient
outcomes.
Those arguments have been largely based
on good treatment
outcomes for talk therapy with fewer side
effects and lower relapse rates, said Greenberg.
She and her colleagues interview each of these women
for several hours every 6 months to try to understand the
effects of genes, crime, poverty, and isolation
on their disease
outcomes.
It may seem surprising to people, but you can look at something like Mars, which has a very thin atmosphere, and you can look at something like Venus which we tend to think of as sort of having this rather heavy, clouded atmosphere, which [is] hellishly warm because of runaway greenhouse
effect, and
on both of those planets you are seeing this phenomenon of the atmosphere leaking away, is actually what directly has led to those very different
outcomes for those planets; the specifics of what happened as the atmosphere started to go in each case [made] all the difference.
The challenge, of course, is to somehow meld a bewildering array of data sets: all sorts of historic and current medical records about each person and all sorts of scientific reports
on a number of drugs, drug tests, potential side
effects and
outcomes for other patients.
For the follow - up study,
outcomes were assessed at 4 years, a time point when any subtle
effects on development should have emerged and can be more reliably assessed.
In addition to postoperative A-fib, researchers are studying,
for example, what factors can improve
outcomes of surgeries performed
on weekends; how many rectal cancer operations a hospital needs to perform
for the best results; and whether having a trauma department confers a beneficial «halo
effect»
on patient
outcomes across the board.
And what
effect does an extremely mobile teacher corps — only one in four taught the same grade at the same school
for both years — have
on student
outcomes?
Tests of drug
effects often rely
on short - term surrogate indicators (say, change in cholesterol level),
for instance, rather than eventual meaningful
outcomes (say, heart attacks).
Of all the mediating factors analysed, the researchers found that a reduction in fear avoidance beliefs (fears that exercise or activity will make symptoms worse, which is an understandable reaction to having CFS) was the strongest, accounting
for up to 60 % of the overall
effect of CBT and GET
on outcomes.
RELAX - AHF was a randomised, double blind controlled trial that evaluated the
effects of a 48 - hour infusion of the intravenous drug, serelaxin,
on clinical
outcomes in 1 161 patients admitted to hospital
for acute heart failure.
The USPSTF found no studies that evaluated the
effect of screening
for OSA
on health
outcomes.
These results need to be interpreted with caution, say the authors, but overall, the financial crisis in Europe seems to have had mixed
effects on health
outcomes, with the evidence being most consistent
for suicides and mental health.
Further analysis was conducted
on two variants
for effects on additional health - care related
outcomes.
Although there was no
effect of dietary sodium
on blood pressure
for those in the low range, there were more deaths and cases of cardiovascular disease
outcomes.
RAND researchers evaluated thousands of studies to assess the available evidence
for the
effect of 13 common gun policies
on a range of
outcomes, including injuries and deaths, mass shootings, defensive gun use, and participation in hunting and sport shooting.
Story number 1: A new study found that praying
for heart surgery patients had no
effect on the patient's medical
outcomes.