Sentences with phrase «effects seen in the report»

Not exact matches

EY's report concludes this emphasis on frugality is because Gen Z have matured in the aftermath of the financial crisis and, having seen the recession's effect on their families, are more careful with their money.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Thus, while concluding that the NGP is likely to result in significant adverse environmental effects with respect to caribou and grizzly bears, the JRP recommended that these «can be justified in the circumstances, as set out in Chapter 2» (see NGP Report, Volume II, Chapter 8, Environmental Assessment).

From a strictly legal perspective, the relevant question is not whether there is a sufficient connection to any particular existing or proposed oil sands development or other production activity, and certainly not whether such projects or activities were included in the Terms of Reference (ToR), but rather simply whether the GHGs associated with the production of bitumen that will be transported by the NGP are an «environmental effect» of that project (see NGP Report, Volume II, Appendix 4, Terms of Reference, which defines «environmental effect» very broadly to mean «any change that the project may cause in the environment.»

The way he sees it, The Globe and Mail's Barrie McKenna and Brent Jang reported, markets have reacted to the changes in mortgage rules «in a way which has in effect engineered a soft landing, a much more comfortable kind of situation.»

Reading breathless media reports about CO2 «pollution» and about minimizing our carbon footprints, one might think that the earth can not have too little CO2, as Simpson thought one couldn't be too thin — a view which was also overstated, as we have seen from the sad effects of anorexia in so many young women.

The ambassador claimed, in his letter to Clinton, that the inspector general report's authors had «failed to read any of my writing or see its highly positive effect on our bilateral relations.»

Also, we have widely reported here on the incredible effects people are seeing in using coconut oil with dementia and Alzheimer's, but not even the Alzheimer's Association is researching about coconut oil, despite being presented with the evidence for it as far back 2007.

Crop estimate reports are mixed in California and it remains to be seen what effects, if any, the draught will have on the coming crop.

See also Lucy Barbour, «Competition watchdog ACCC head Rod Simms (sic) denies claims an «effects test» would be «economically dangerous» (ABC Rural, 18 August 2014), in which the ACCC Chairman defends the ACCC's proposed effects test (and is also reported as saying that the current case against Coles was brought under the unconscionable conduct provisions rather than under s 46 because the misuse of market power prohibitions is a law that exists only between competitors...)

There has been plenty of media on the Harper Review's draft report released last Monday - including two items in today's AFR: Kate Walsh, «Lawyers see green light for mergers in Harper review» (The Australian Financial Review, 30 September 2014, page 15) and an opinion piece by former Competition Minister, Craig Emerson: «There are ill - effects in an effects test» (The Australian Financial Review, 30 September 2014, p 58).

In most cases, the surcharges were initially met with hostility, but the positive effects have been hard to deny: Immediately following the initiation of zone charging, London saw congestion reduced by a quarter, average speeds increase by 30 percent, and carbon dioxide emissions decrease by 20 percent, per the Fix NYC report.

«We've seen the egregious effects bias - based harassment has on students when there is a failure to intervene, from the violence at South Philadelphia High School in 2009 to reports we received in years past from the former Lafayette High School in Brooklyn,» Mariadason said.

The lingering gravitational effects of a star that passed by our solar system some 70,000 years ago can be seen in the movements of dozens of comets today, Gizmodo reports.

Kathmandu's basin of soft sediments helped amplify low - frequency waves, as seen in its destructive effect on taller buildings, says Youssef Hashash, an earthquake engineer at the University of Illinois, Urbana - Champaign, and the lead author of a report published last week that documented the quake's damage to infrastructure.

Patterns in the waves, when analyzed as if seen by an accelerating observer, appear to re-create the expected signature of the effect, researchers report September 7 at arXiv.org.

The group has also seen this beneficial effect in germ - free piglets, whose physiology is more humanlike than mice, they report.

Dr. Minako Ueda, Dr. Masakazu Nambo of the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University and their colleagues have reported in the journal Plant and Cell Physiology, on the development of a series of triarylmethane compounds, which were tested on plant cells to see their effect on cell division.

The new imaging technique will allow researchers to see the effects of novel drugs on this final stage in the parasite's invasion strategy, researchers report online on this week in Cell Host & Microbe.

We included prospective cohorts with at least 50 cardiovascular disease events (mortality, morbidity, or both) to minimise the potential for reporting bias, in which large but unreliable effects might be seen in small studies.

Although the differing effects of hypoxia reported here are in conflict with previously published data, where no contrasting effect was seen (18 — 20), our data was produced using 13 primary breast cancer samples, as well as established cell lines, and the opposing effects in hormone receptor — positive and negative tumors, measured using multiple in vitro and in vivo CSC assays, were consistent in all cases.

Few of the tested effects of rapamycin in our dataset were seen only in aged mice, not in young animals (RER, fat mass, γδ T cells, and CD44hi T cells); however, previous reports have shown aging - independent effects of mTOR inhibition on CD44 expression in T lymphocytes and fat mass (30, 31, 34).

But I've seen other doctors report that the effects are different on a European or European - American population than on Asian populations (those studies were on its effects in Asian women), and that for most American women, green tea actually enhances estrogen production and leads to higher incidence of estrogen - driven cancers.

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasein neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasein the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasein a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseaseIn addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasein most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasein the treatment of convulsion diseases.

Because of the effective use of the ketogenic diet in reducing seizures (see above), it has been suggested that it may also improve the clinical status in brain injury, especially by reducing the incidence of long - term consequences, such as epilepsy.79 Positive effects of a ketogenic diet have also been reported in reducing the cortical contusion volume in an age - dependent manner in an animal model of cortical injury, which is related to the maturation - dependent variability in brain ketone metabolism.92 These findings were also supported by the demonstration that a ketogenic diet reduced post-traumatic cognitive and motor function impairment, at least in a rat model.93

Although these relatively small - scale intervention trials using viscous Functional Fibers have reported substantial cholesterol - lowering effects and therefore should be protective against CHD, no protective effect against CHD was seen in a large - scale clinical trial with individuals who had a previous myocardial infarction (Burr et al., 1989).

In addition, an inverse relationship between cereal and cereal fiber intake and colon cancer incidence was reported in 24 studies although 7 other studies did not see this effect (Jacobs et al., 1998In addition, an inverse relationship between cereal and cereal fiber intake and colon cancer incidence was reported in 24 studies although 7 other studies did not see this effect (Jacobs et al., 1998in 24 studies although 7 other studies did not see this effect (Jacobs et al., 1998).

However, it should be noted that the positive effects seen in two large prospective studies (Salmerà ³ n et al., 1997a, 1997b) were achieved with the same levels of fiber that have previously been reported as being protective against CHD (Pietinen et al., 1996; Rimm et al., 1996; Wolk et al., 1999).

After the wild sensation over his show last Autumn, when American step dancers paraded his clothes in a choreographed performance, it was reported that orders went up as much as 20 percent, but Owens doesn't see cause and effect there.

It's a pleasure, therefore, to report that Dawn has a much more focused script, that its special effects are as impressive as any seen in this summer's blockbusters, and for those looking for a bit of substance, the film actually has a dark message about humanity and war.

This can be seen in Table 10, which reports estimates of charter and pilot effects using the two designs.

Related, I should note that in a few places the authors exaggerate how, for example, teachers» effects on their students» achievement are so tangible, without any mention of contrary reports, namely as published by the American Statistical Association (ASA), in which the ASA evidenced that these (oft - exaggerated) teacher effects account for no more than 1 % -14 % of the variance in students» growth scores (see more information here).

Secretary DeVos is right when she says that American state schools appear to have grown accustomed to being in receive mode, waiting for orders from on high as to what they are to do next; while independent schools continue to enjoy their autonomy and capacity for innovation, which was once a rationale for the charter sector as well, but that sector has lost its vitality since philanthropists suborned leading educational entrepreneurs into specializing in test prep, so impatient did they become to see the effects of their spending reflected in national test score reports, an improvement that has not been forthcoming.

60 % of school districts in New Jersey report they include student voice in school board meetings to some effect (see «More Info» below).

Seeing effect sizes like those reported in Figure 1.1 tells us that goal setting has a general tendency to enhance learning.

This Cause and Effect Tree Book Report Project contains a bulletin board display of 11 of these signal words (see visual example in Extra Goodies section below.)

A positive effect on your co-signer's credit score will come about if you pay off the loan as a part of the consolidation and have the account closed and notated as «paid in full» on the credit report will see the benefit on their credit as that obligation (or potential obligation) is removed from their credit report.

I want to be able to see in reports the effects of exchange rate flux, e.g. as one currency is worth less relative to the other, I want to see my net worth as expressed in the second currency decline.

Some patients are reported to be sensitive to pyridostigmine bromide (Mestinon Rx) but I haven't actually seen skin rash listed as a side effect, just cautions about using this medication in patients who are sensitive to it.

11/24/09 - Philly Dawg - Crusading for puppies and pigeons 11/21/09 - The Philadelphia Inquirer - Flight to Ohio rescues «puppy mill» dogs 11/02/09 - Pet News and Views - Ohio Dog Auctions Affects All of Us 11/01/09 - Thoughts Fur Paws - Ohio Dog Auction Ban Needs Signatures 10/30/09 - Best Friends Animal Society (Puppies Aren't Products)- Ohio Petition to Ban Dog Auctions 10/30/09 - Ohio.com (Akron Beacon Journal)- Puppy mills muddy Issue 2 debate 10/26/09 - Animal Law Coalition - Ballot Initiative to Stop OH Dog Auctions 10/21/09 - Philly Dawg, Wednesday Wag Oct. 21 - Under the Capitol dome 10/16/09 - Pet News and Views - Dog Auctions and Puppy Mills 10/14/09 - Cleveland Plain Dealer - Group gets OK to pursue dog law 10/14/09 - The Columbus Dispatch - Group gets OK to pursue dog law 10/14/09 - 89.7 WKSU - Effort to ban dog auctions gets approval to gather signatures 10/13/09 - Cincinnati.com - Signature gathering OK'd for dog auction measure 10/13/09 - Dayton Daily News - Signature gathering OK'd for dog aucion measure 10/13/09 - Fox 59 Indianapolis - Ohio panel clears way for supporters to gather signatures to ban dog auctions 10/13/09 - Mansfield News Journal - Signature gathering OK'd to pursue dog law 10/13/09 - Springfield News Sun - Signature gathering OK'd for dog auction measure 10/13/09 - Toledo on the Move - Possible state ban on dog auctions 10/13/09 - Vindy.com Newswatch - Signature gathering approved for dog - auction measure 10/13/09 - WKYC.com - Signature gathering OK'd for dog auction measure 10/13/09 - WLIO.com - Signatures for ban on dog auctions OK'd 10/13/09 - Gongwer Ohio Report - BALLOT BOARD MOVES DOG AUCTION ACT FORWARD 10/13/10 - Statehouse News Bureau - Animal - rights advocates get their proposal banning dog auctions closer to the ballot 10/13/09 - Jennifer Brunner, Ohio Secretary of State - Ohio Ballot Board Approves Dog Auctions Act as One Subject Issue: Petitioner Group May Begin to Circulate 10/05/09 - Jennifer Brunner, Ohio Secretary of State - Certification / Initiative Petition proposing the «Ohio Dog Auctions Act» 10/02/09 - Richard Cordray, Ohio Attorney General - Statewide Ballot Issues Update 09/29/09 - Philly Dawg - «PA kennels shed breeding stock before new kennel law takes effect» 06/10/09 - The Columbus Dispatch - Critics seek ban on dog auctions, see link to «puppy mills» 03/25/09 - The Budget (Sugarcreek, Ohio)- Puppy mill protesters promote awareness in Holmes County 02/28/09 - The Columbus Dispatch - Animal advocates may push for ban on dog auctions 03/07/08 - Newsday - Dog auctions a controversial topic

This alleged person is apparently in the Mass Effect 4 development team at Bioware, and when asked by B - TEN whether to publish this information or not, he replied «You are allowed to report any information you see fit.

Since Facebook's algorithm is notoriously unreliable, I thought I would republish two such brief reports, about works I saw in the past two days, especially since the works presented here propelled me into the studio, an effect of art work that I particularly noted when I began this blog.

It is a sweeping and valuable cross-disciplinary description of ways in which climate and ocean dynamics, pushed by the planet's human - amplified greenhouse effect, could accelerate sea level rise far beyond the range seen as plausible in the last report from the Intergovernmental Panel on Climate Change and the most recent review of what leading experts on sea level think, this 2014 paper: «Expert assessment of sea - level rise by AD 2100 and AD 2300.»

Kristin Møller Gabrielsen of the Norwegian University of Science and Technology in Trondheim and colleagues report in the journal Environmental Research that they examined the liver, muscle and kidney tissues taken from seven polar bears killed by Inuit hunters in East Greenland in 2011 and analysed the effect of more than 50 contaminants in plasma samples from Ursus maritimus, to see what effect organohalogen compounds could have on the bears» thyroid systems.

with the effect that we see on flora and fauna today, i will start believing in such a period, when i see the first medieval report about zebras in middle europe.

They suggest testing the following changes in the PHPP and seeing what effect they have on the reported frequency of overheating:

It will be interesting to see whether IPCC will revise its stand on «the range and effects of natural forces» in its next AR5 report, or if it will continue to stick to its old AGW party line of relegating these to secondary importance if not irrelevance.

Using data from 765,000 survey respondents in the United States from 2002 to 2011, coupled with nighttime temperature data, the researchers found that higher nighttime temperatures are associated with self - reported sleep problems, with the largest effects seen during summer and among lower - income and elderly subjects (who may not have easy access to air conditioning).

The «poor fits» in ocean oscillation effects for 1900 - 1920 (and beyond) in this report combined with the magnetic «poor fit» of 1900 - 1920 would actually cancel each other to cause the measured temps pretty well... Can you see what I mean?

Smith, who is the convening lead author of the second working group report on vulnerability to climate change, says: «The new assessment has increased our confidence that the effects for climate change are beginning to be seen, in terms of rise in temperature, sea levels and heavy precipitation events».