Sentences with phrase «effects than function»

It emerges that function at new active sites may be more sensitive to long - range effects than function at «old» highly evolved active sites.

Not exact matches

This team also discovered 3,200 genes that had fewer loss - of - function or missense mutations than would be expected suggesting that these are likely disease - causing variants that are rare or absent in the population because of their detrimental effect on human health.

For, while Hartshorne allowed for the reality of structured societies and only specified that their unity as compound individuals was effected through the presence and activity of a dominant personally ordered subsociety, Ford equivalently wants to eliminate the reality of structured societies altogether, at least insofar as they function as compound individuals rather than as simple aggregates of occasions.

He said: «A decade on from the passing of the controversial anti-smacking law in New Zealand, the law has maintained its very high level of opposition, but most significantly the law has had a «chilling» effect on parenting, and rather than tackling rotten parents who are abusing their children, it has targeted well - functioning parents».

Finding a way to reconcile two competing demands - minimizing contact in practice in order to reduce the number of concussions sustained and the number of hits players sustain over the course of a week and a season that emerging science, now more than ever, suggests may have a deleterious cumulative effect [26] on a player's cognitive function over the long term, while at the same time maximizing the amount of time in practice learning how to tackle and block without head - to - head contact - time that is needed to maximize the protective effect of proper tackling on the number of head - to - head hits players sustain in game action, which can not only result in concussion, but catastrophic neck and spine injuries - is challenging, but clearly not impossible.

Its content in breast milk is variable26 and depends on DHA sources in the maternal diet, 6,27 including fish; infant DHA status in turn depends on the DHA content of ingested breast milk.27 Randomized trials of DHA supplementation during lactation have found beneficial effects of DHA on early motor skills28 and sustained attention29 but not visual motor function or general cognition.28, 30 Our observation may be explained by DHA or nutrients in fish other than DHA.

Until sleep debt is paid back, it's fine to sleep longer than usual; one study found that just one 10 - hour sleep session significantly improved cognitive function following five nights of sleep deprivation Neurobehavioral dynamics following chronic sleep restriction: dose - response effects of one night for recovery.

However, research has shown that a 1 - hour nap has many more restorative effects than a 30 - minute nap, including a much greater improvement in cognitive functioning.

«The work demonstrates that the protective effects of HDL are more dependent upon how it functions than merely how much of it is present,» Rader concluded.

The study also did not have information on children's exposure to swimming pools, which contain much higher chlorine levels than domestic water and could have an additional detrimental effect on skin barrier function and risk of eczema.

Light in the morning — more than any other time of day — leads to powerful brain - boosting effects, helping us to function as best we can, despite the approaching winter.

According to Kramer, their side effects are fewer than we might think, they dramatically reduce the risk of recurrent depressive episodes, and even if they aren't a cure, the person still functions fairly well.

However, for women, endothelial function and the effect of exercise may be related more to menopausal status than fitness.

Mohan says most studies of ataxins and related proteins had focused on the effects of the polyglutamine - expanded versions, rather than the function of the unaltered protein.

Based on the included studies, mainly performed in well - nourished subjects, the combined effect of dietary supplementation on muscle function was less than expected.

The team found that protein intake greater than the RDA had no significant effect on lean body mass, fat mass, muscle performance, physical function, fatigue or other well - being measures.

The mean physical function score was 6 points higher in the GES group than in the control group, consistent with a statistically significant but relatively small effect.

The Review found that compared to no exercise, practising yoga might improve back - related function and may also reduce symptoms of lower back pain by a small amount in the first six to twelve months, although the effect was consistently less than that judged to be clinically important.

A major target of such poor development is the gut and thus any abnormality in gut nerve development (the gut contains more neurones than the spinal cord) would have a significant effect not only on gut functions and probably gut microbiome, but also on information flowing back to the brain that may cause interference in normal brain functions, perhaps precipitating ASD - like behaviour in a developmentally challenged brain.

(6) This is consistent with the deleterious effect of such cells on tissue function, and with the researchers» conclusion that «the observed improvements in skeletal muscle and fat of late - life treated 10 - month - old BubR1H / H; INK - ATTAC - 5 mice reflect attenuated progression of age - related declines rather than a reversal of ageing».

The CDR potential and possible environmental side effects are estimated for various COA deployment scenarios, assuming olivine as the alkalinity source in ice ‐ free coastal waters (about 8.6 % of the global ocean's surface area), with dissolution rates being a function of grain size, ambient seawater temperature, and pH. Our results indicate that for a large ‐ enough olivine deployment of small ‐ enough grain sizes (10 µm), atmospheric CO2 could be reduced by more than 800 GtC by the year 2100.

Their effect on cell fate and function is far wider than we initially thought.

Citing several animal studies, the AAEM concludes, «there is more than a casual association between GM foods and adverse health effects» and that «GM foods pose a serious health risk in the areas of toxicology, allergy and immune function, reproductive health, and metabolic, physiologic and genetic health.»

The conclusions of the study were that a protein intake greater than the RDA amounts had no significant effect on lean body mass, fat mass, muscle mass (or performance), athletic function, fatigue, or other well - being measure.

There are a couple of reasons why menopausal women might be experiencing more digestive problems than previously: hormonal imbalance disrupts the natural transit of food in the gut, and stress has an adverse effect on the normal functioning of hormones.

The ill effects on the thyroid range from abnormal thyroid function test findings to overt thyroid dysfunction, with hypothyroidism resulting more commonly than hyperthyroidism.

For example, cognitive behavioral therapy (CBT) had small positive effects on disability and catastrophic thinking.66 Exercise therapy reduced pain and improved function in chronic low back pain54; improved function and reduced pain in osteoarthritis of the knee51 and hip52; and improved well - being, fibromyalgia symptoms, and physical function in fibromyalgia.48 Multimodal and multidisciplinary therapies helped reduce pain and improve function more effectively than single modalities.55, 67 Multiple guidelines recommended acetaminophen as first - line pharmacotherapy for osteoarthritis68 - 73 or for low back pain74 and nonsteroidal anti-inflammatory drugs (NSAIDs) as first - line treatment for osteoarthritis or low back pain70, 74; first - and second - line drugs for neuropathic pain include anticonvulsants (gabapentin or pregabalin), tricyclic antidepressants, and serotonin - norepinephrine reuptake inhibitors (SNRIs).75 - 78 Nonsteroidal anti-inflammatory drugs have been associated with hepatic, gastrointestinal, renal, and cardiovascular risks.63, 73,79

If we equate de facto ketogenic diets with high - protein diets (which is not always correct) then the risks proposed by critics of this type of dietary approach are essentially those of possible kidney damage due to high levels of nitrogen excretion during protein metabolism, which can cause an increase in glomerular pressure and hyperfiltration.12 There is not wide agreement between studies; however, some infer the possibility of renal damage from animal studies, 99, 100 whereas others, looking at both animal models, meta - analyses and human studies, propose that even high levels of protein in the diet do not damage renal function.101, 102 In subjects with intact renal function, higher dietary protein levels caused some functional and morphological adaptations without negative effects.103 There may actually be renal - related effects, but on blood pressure rather than morphological damage.

However, since PCSA is expected to increase to a greater extent than anatomical cross-sectional area because of the compensatory effects of pennation angle, this is likely a function of methodological weaknesses rather than any failure of resistance - training to produce meaningful changes in PCSA.

Models of student achievement in a given year as a function of prior achievement and other controls tend to give higher correlations than other models, see: Daniel F. McCaffrey, Tim R. Sass, J. R. Lockwood, and Kata Mihaly, «The intertemporal variability of teacher effect estimates,» Education Finance and Policy, 4, no. 4, (2009): 572 - 606.

There's a sliding roof function too, which creates a sunroof type effect rather than lowering the whole roof.

This effect is again a function of options moneyness but this time, in the money put options raise in extrinsic value more than out of the money put options.

The daily reset function means investors holding DGAZ for periods of longer than one trading day will be exposed to the effects of compounding, and could see returns vary greatly from the headline -3 x exposure.

By solving each of them using the «Effect» function, it becomes very clear which rates are higher than others in terms of annual, real returns.

The goal of therapy is to restore normal thyroid function and minimize side effects of treatment without creating lower than normal levels of thyroid hormones (referred to as hypothyroidism).

The paper goes a lot more in depth than that, it basically shows that you can enhance specific brain functions through playing video games and that this effect is so pronounced it even shows up on brain scans.

Agree Deus EX very strong reboot of a great 2 year old game, but for my money AC4 is the best 3rd party game on WiiU... it is technically nealry flawless... Better textures, lighting, effects, and framerate than ps360 versions, get this quick load times (I think the 1.1 gb update on first boot is a core component install), all extra functions like uplay, comapnion app, and online are working and its an awesome game.

By that time, I really had to give up thinking what holds the concept together other than the list of fifty - six works, in effect the gallery's own function with fifty - six arguments.

This is why (absent sufficient solar or other non-LW heating) the skin temperature is lower than the effective radiating temperature of the planet (in analogy to the sun, the SW radiation from the sun is like the LW radiation, and the direct «solar heating» of the part of the atmosphere above the photosphere may have to due with electromagnetic effects (as in macroscopic plasmas and fields, not so much radiation emitted as a function of temperature).

His conclusion was that the CO2 forcing is unquestionably logarithmic, so that each additional molecule we emit has less forcing and warming effect than its predecessors; that the precise value of the coefficient in the CO2 forcing function, which the IPCC has already reduced by 15 %, can not be determined; and that, all things considered, 1 K per doubling was probably in the right ball - park.

• Poles to tropics temperature gradient, average temp of tropics over past 540 Ma; and arguably warming may be net - beneficial overall • Quotes from IPCC AR4 WG1 showing that warming would be beneficial for life, not damaging • Quotes from IPCC AR5 WG3 stating (in effect) that the damage functions used for estimating damages are not supported by evidence • Richard Tol's breakdown of economic impacts of GW by sector • Economic damages of climate change — about the IAMs • McKitrick — Social Cost of Carbon much lower than commonly stated • Bias on impacts of GHG emissions — Figure 1 is a chart showing 15 recent estimates of SCC — Lewis and Curry, 2015, has the lowest uncertainty range.

That is, while the roles of water vapour and cloud effects are very important in the net greenhouse effect, they function as feedbacks rather than primary drivers of change.

People exposed to infrasound and low - frequency noise in a laboratory (at much higher levels than those to which people living near wind farms are exposed) experience few, if any, effects on body functioning.

Dr Gawande notes that, although many practitioners are resistant to the use of checklists, the ultimate effect is to create well - functioning teams and that, rather than stifling creativity, the checklists actually foster it.

Unless the effects of imbecilic and reactionary political dictatorship are even worse than many fear, a functioning and progressive legal machine will continue to operate in one way or another.

The Court chose to indulge these concerns and take the politically easy way out by ruling that EU law (including the Charter) is not applicable to visa applications that would lead to a stay of more than 90 days — instead of ruling for the application of the Visa Code and thus also the Charter of Fundamental Rights, as it would then have been confronted with the impossible task of having to interpret the Charter in a way that would not have a negative effect on the functioning of the Dublin system.

The function of absolute immunity in the performance of judicial duties is not to shield members of the judiciary from liability for their own misconduct, but rather «to protect their offices from the deterrent effect of suit alleging improper motives where there has been no more than a mistake or a disagreement on the part of the complaining party with the decision made.»

Multiple studies on the therapeutic effects of «expressive writing» like poetry found that penning unexpressed feelings for less than an hour a day has positive effects on «frequency of physician visits, immune function, stress hormones, blood pressure, and a number of social, academic, and cognitive variables.»

Rather than simply using it for a Portrait Mode - like function, where the background of a subject is blurred for a cool DSLR effect, Motorola is also offering a wide - angle mode, like LG's V30 and G6, and a few other neat tricks.

It seems that insecure attachment may be more than just toxic to relationship functioning - it could be somewhat corrosive, having long - term, downstream effects on relationships that continue to get worse as the years go on.