They were also more sensitive to alcohol's
effects than the normal mice were; studies have shown that the more sensitive a person is to alcohol, the less likely he or she is to abuse it.
Not exact matches
To investigate the longer - term
effects of higher -
than -
normal acetylcholine levels on the brain, Hermona Soreq of the Hebrew University of Jerusalem and her colleagues first induced high levels of acetylcholine by forcing 26
mice to swim, an activity stressful to
mice.
To see if the
effect also works in reverse, the team asked whether
mice grown in a germ - free environment would express genes encoding complement components differently
than mice grown under
normal conditions.
It should be noted, however, that while a study on senescent cell ablation in genetically
normal mice would provide at least some evidence on the
effect of senescent cells (and their ablation) on promoting cancer, even such a study would likely show less
effect than could be anticipated in a large mammal model, since even normally - aging
mice rarely suffer metastatic disease to the extent of aging humans, as sheer primary tumor volume is generally sufficient to be fatal to
mice.