Sentences with phrase «efficacy endpoint»

The phrase "efficacy endpoint" refers to a measurable result or outcome that is used to determine the effectiveness or success of a treatment or intervention. It is a specific goal or target that is used to evaluate whether a treatment is achieving its intended purpose. Full definition
In mid October, the company reported that Persist, the Phase 3 clinical trial for its Posimir pharmaceutical, did not meet its primary efficacy endpoint of reduction in pain on movement over the first 48 hours after surgery as compared to standard bupivacaine HCl.
Of the 1,952 patients randomised in ION - 1, ION - 2 and ION - 3, 1,886 patients (96.6 %) achieved the primary efficacy endpoint of SVR12.
The secondary efficacy endpoints include: BCVA reported in LogMAR at 2 - Years post-treatment in the second affected / not yet affected eye compared to both placebo and the first affected eye receiving GS010, OCT, color and contrast sensitivity and quality of life scales.
Wrote the company charter for the Clinical Events Committee (CEC) and collection of clinical data including management of the CEC discussion of adjudication and classification of suspected safety and efficacy endpoint events
Principal efficacy results The trial achieved its primary efficacy endpoint of demonstrating a reduction in one or more of these key biomarkers.
Renal denervation failed to achieve the primary efficacy endpoint of a decrease in systolic blood pressure measured in the doctor's office from baseline to six months or the powered secondary efficacy endpoint of decrease in average 24 - hour levels by ambulatory blood pressure monitoring, which provides more reliable readings.
In January 2014, Medtronic announced that it was halting its U.S. pivotal trial on renal denervation because the study had failed to reach its primary efficacy endpoint, though it did meet its primary safety endpoint.
Patients were randomised to TAF 25 mg daily or to TDF 300 mg daily and the primary efficacy endpoint was the percent of patients with HBV DNA below 29 IU / mL at week 48.
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