Not exact matches
Other humanized
mice have no spontaneous phenotype and can be combined with either genetic spontaneous or inducible models of chronic inflammatory diseases yielding preclinical
efficacy evaluation platforms for Rheumatoid Arthritis, Intestinal Inflammation, Psoriasis and Multiple Sclerosis.
The generation, characterization and use of transgenic
mice for the preclinical
efficacy evaluation of therapeutics constitute one of the main R&D activities of Biomedcode.
TghIL17A
mice in combination with induced psoriasis protocols form a drug
efficacy evaluation platform for testing anti-huIL17A therapeutics.
Today our rich collection of arthritis
mouse models is widely used for the preclinical
evaluation of the
efficacy of anti-arthritic pharmaceuticals and offer an ideal platform for establishing proof of concept for novel technological advances.
Collagen Antibody Induced Arthritis (CAIA) is a simple
mouse model of rheumatoid arthritis that can be used for the fast preclinical
efficacy evaluation of candidate therapeutic agents targeting pathogenic mechanisms and inflammatory processes of arthritis.
Promising drug compounds that pass the initial
evaluation process at Gladstone will be fast - tracked for pre-clinical testing at ALS TDI, which will assess the compounds for activity and
efficacy in various
mouse models of human neurodegeneration.