«As we identify which bacteria have a similar effect in humans, it should be possible to develop probiotic supplements that specifically
improve efficacy of immunotherapies,» he says.
We offer a number of immunophenotyping kits to evaluate
the efficacy of any immunotherapy against cancer (e.g., CD3 -, CD117 -, CD71 -, and CD25 - expressing cells) and to determine CD4 expression by T cells and macrophages in HIV - infected patients after highly active antiretroviral therapy (HAART).
Dr. Gnjatic's research focuses on human antigen - specific immune responses to tumor antigens, in an attempt to define new targets for the development of cancer immunotherapies, assess
the efficacy of these immunotherapies, and learn why they may fail.
«The most exciting finding was that TAM reprogramming greatly improved
the efficacy of immunotherapy,» says Michele De Palma.
Our objective is to use our microbiome therapeutic approach to improve
the efficacy of immunotherapy in patients with life - threatening cancers.»
In an effort to improve
the efficacy of immunotherapy for solid tumors, Fred Hutch researchers have engineered a new type of protein that can rewire a «kill switch» to stimulate T cells» activity instead.