Sentences with phrase «efficacy of its approach in»

«Though we do not doubt Your Excellency's bona fide concerns for the peaceful resolution of the crises, we nevertheless have reservations as to the efficacy of this approach in ensuring lasting solutions,» the letter said.

They said: «Though we do not doubt Your Excellency's bona fide concerns for the peaceful resolution of the crises, we nevertheless have reservations as to the efficacy of this approach in ensuring lasting solutions.

Building on strong drug discovery and early clinical development expertise, iTeos intends to demonstrate the clinical efficacy of its approach in proof of concept trials, on its own or in co-development with a partner.

A randomized controlled trial of My Teaching Partner — Secondary — a Web - mediated approach focused on improving teacher - student interactions in the classroom — examined the efficacy of the approach in improving teacher quality and student achievement with 78 secondary school teachers and 2237 students.

Recent work in using problem - based learning in teaching science to high ability learners at the elementary level suggests the efficacy of the approach in enhancing student and teacher motivation (VanTassel - Baska, Bass, Ries, Poland, & Avery, 1998); in improving problem - finding abilities (Gallagher, Stepien, & Rosenthal, 1992); and in promoting intra and interdisciplinary learning (Stepien, Gallagher, & Workman, 1993).

The objectives of this manuscript are to: 1) describe the use of GIS technology in developing and tracking a data - based target for decreasing shelter intake; 2) discuss the types of interventions used in the attempt to decrease intake and 3) document the efficacy of this approach in decreasing shelter intake.

Research has also demonstrated the efficacy of the approach in the treatment of eating disorders, sibling attachment issues, and certain behavioral concerns.

Not exact matches

While this approach to investing can be challenging at times when we find ourselves on the wrong side of market trends, our confidence in its efficacy over a long - term investment horizon is unwavering.

Personally I am not a fan of these types of structured programs because 1) there is not adequate research to support their efficacy and 2) they approach literacy development in a highly contrived manner.

Although professional lactation support can improve the duration of overall breast feeding, its effect in improving exclusive breast feeding is unclear.11 18 22 Thus far, studies that report improvement of rates of exclusive breastfeeding have involved mainly community based peer counselling strategies.23 24 25 Even then, a randomised trial in the UK recently cast doubt on the efficacy of this approach.26 There are current recommendations from NICE for the UK - wide implementation of the baby friendly initiative.4 5 6 The 2006 NICE costing report on routine postnatal care of women and their babies estimates that efforts to improve rates of breast feeding will result in substantial cost savings for the NHS.6

There is a need for interdisciplinary teams of experts in fields such as reproductive health, nutrition and child development to work together to assess the efficacy and effectiveness of various approaches.

It helps to clarify the pre-existing evidence on the effectiveness of these approaches and their side effects in the short term, as well as introducing longer term evidence of efficacy and safety.

Further trials are planned to document the efficacy and safety of the combination in patients infected with the other HCV genotypes and in particularly vulnerable groups, to enable a public health approach to the treatment of hepatitis C.

Given the lack of evidence to support the efficacy of antidepressants in bereavement, physicians should take a conservative approach in prescribing to avoid overtreatment.»

A new study led by University of Kentucky researchers suggests a new approach to develop highly - potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer as well as viral and bacterial infections.

The study, published in PLOS Computational Biology, provides a patient specific approach to tuning parameters that may dramatically improve efficacy of deep brain stimulation.

Some have raised concerns about the safety and efficacy of the procedure, saying the team should have tested the approach in animals first.

«We are at a point in our research where we have validated the efficacy of this combination treatment approach in preclinical animal models, and we now need to define its safety through toxicology and pharmacology studies,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at VCU Massey, chairman of VCU School of Medicine's Department of Human and Molecular Genetics and director of the VCU Institute of Molecular Medicine.

This visual abstract depicts how Wei et al. utilize single - cell phosphoproteomic analysis of patient derived glioblastoma models to identify shifts in signaling coordination following short - term treatment with kinase inhibitors, which facilitates the design of combination therapy approaches with reduced resistance and improved efficacy.

According to Choe's research team, the current «attract - and - kill» approach, once it is successfully implemented in practical pest management programs, could potentially provide maximum control efficacy with reduced amount of insecticides applied in the environment.

«Efficacy of new gene therapy approach for toxin exposures shown in mouse study.»

While humanized mouse models provided a logical first approach to examine in vivo efficacy of CXCR4 disruption, this system does not make it possible to fully assess the functional impact of CXCR4 loss on CD4 + T cell function.

The Transcriptomics Core Facility supports a systems biology approach in vaccine development focusing on the identification of transcriptomic correlates of vaccine immunogenicity and efficacy for a range of novel and licensed vaccines using PBMC or whole - blood and BAL fluid samples.

Our objective is to use our microbiome therapeutic approach to improve the efficacy of immunotherapy in patients with life - threatening cancers.»

We also develop in silico chemogenomic approaches to analyze jointly the chemical space of small molecules and biological space of protein targets, leading in particular to efficacy profile and secondary effect prediction.

«The objective of the Clinical Cell Therapy Program is to develop new methods to regrow heart muscle and blood vessels, and evaluate the efficacy of these methods as an approach to improving heart function in patients with a variety of heart disorders,» said Anthony DeMaria, M.D., director of the Sulpizio Family Cardiovascular Center at UC San Diego.

Title: Combining efficacy and completion rates with no data imputation: a composite approach with greater sensitivity for the statistical evaluation of active comparisons in antipsychotic Trials Author: J. Rabinowitz et al..

• Personalized drug safety can be addressed with patient - derived cells in Organ - Chips, enabling a patient - specific approach for assessing the safety and efficacy of new candidates while taking into account patient variability and the unique biology of individual patients.

Lysogene collaborates with University of Massachusetts Medical School (UMMS) for pre-clinical efficacy studies of innovative AAV - based gene therapy approaches in the GM1 gangliosidosis mouse model.

Current evidence from studies in rodents and humans suggests that IER is capable of promoting weight - loss and / or favourably influencing an array of cardiometabolic health indices, with equal or greater efficacy than conventional continuous ER approaches.

The efficacy and necessity of these drugs has long been debated in the natural health world — mainly questioning whether the absolute benefit of the drug justifies the lifetime prescription or whether the approach of «blocking» cholesterol makes sense given that cholesterol is vital for so many other areas of human health — but for those that do decide to take Lipitor, Crestor or other statins, it's important to consider the drug's other effects on the body.

The efficacy of innate immunity targeted therapeutic approaches (like diet) reiterates the continued role of innate immunity in type 1 and type 2 diabetes.

Dr. Walker uses team - based decision making to advise his patients on the safety and efficacy of herbs, nutrients, food - based and lifestyle approaches so that they can be confident in their comprehensive plan of care.

``... in order to better understand the pathogenesis of AD [Alzheimer's Disease], to study and to monitor the activity and the efficacy of new therapeutic approaches such as KD [Ketogenic Diet] and, finally, to develop a personalized management of the disease».

FODMAPs: Efficacy and Basis for Use in IBS DIET SOURCES OF RAPIDLY FERMENTABLE CARBOHYDRATES Lactose Fructose Fructans GOS Polyols THE FODMAPS APPROACH Got lactose intolerance?

In Edutopia's integrated studies research review, discover seven key approaches in effective curriculum integration, get our specific recommendations on evidence - based practices and programs, learn about pitfalls to avoid, and dig into an annotated bibliography of studies supporting the efficacy of integrated studies practiceIn Edutopia's integrated studies research review, discover seven key approaches in effective curriculum integration, get our specific recommendations on evidence - based practices and programs, learn about pitfalls to avoid, and dig into an annotated bibliography of studies supporting the efficacy of integrated studies practicein effective curriculum integration, get our specific recommendations on evidence - based practices and programs, learn about pitfalls to avoid, and dig into an annotated bibliography of studies supporting the efficacy of integrated studies practices.

The efficacy of running one - to - one programs in schools is that, through this approach to technology education for students, teachers and families, schools are providing a laboratory of trial and error and figuring out a way to make sense of the fast - changing world of technology.

Some school districts have reported decreases in court referrals after implementation of SRO programs, especially for minority students, but there is little rigorous evidence on the efficacy of this approach.

While little impact - evaluation research exists on the efficacy of early - warning indicator systems in reducing the use of exclusionary discipline, implementation research suggests that if early - warning systems are not paired with a behavioral - support approach, they are unlikely to be effective.

An IPPR report, «Freedom's Orphans», published in 2006 described the way that the efficacy of low SES communities was depressed, and how a particular approach to education both inside and outside of the classroom could impact on this.

The modern information - processing approach in cognitive psychology would recommend careful analysis of the goals of instruction and thorough empirical study of the efficacy of instructional approaches.

Unfortunately, unlike in the other briefs in the Carnegie Knowledge Network (CKN) series, there is little evidence about the efficacy of these various approaches.

Heafner and Friedman's (2008) study on the use of wikis demonstrated a pedagogical shift from traditional teacher - centered instructional approaches to student - oriented, constructivist learning, which resulted in increased student self - efficacy and motivation (p. 288).

TXCC will support TEA in gathering the most effective and useful approaches to instructional leadership by convening stakeholders and investigating the efficacy of approaches being used across all five contractors, identifying key components and variables, and providing consulting services to help the agency plan and develop a new state model of instructional leadership for ESC implementation.

This core element of the Mills Teacher Scholars approach to collaborative inquiry plays a central role in creating the conditions for authentic teacher learning, modeling teacher curiosity about their practice and building collective teacher efficacy.

This core element of the Mills Teacher Scholars approach to collaborative inquiry plays a central role in creating the conditions for authentic teacher learning and building collective teacher efficacy.

The Efficacy Institute approach is built on three elements: building consensus on clear targets for academic proficiency; building belief among teachers, parents, and children themselves that proficiency standards can be achieved; and then building a continuous stream of feedback from student assessments to drive changes in curriculum and instructional strategy.

Ten working groups are investigating the role of efficacy research as it relates to (a) K - 12 district and school decision making, (b) higher education decision making, (c) research spending, (d) evidence and quality of efficacy in research approaches, (e) institutional competence, (f) investors and entrepreneurs, (g) the role of federal goals and funding, (h) educational philanthropies, (i) end users, and (j) crowdsourcing.

Amgen's approach is to understand the fundamental biological mechanisms of disease in order to determine what type of medicine is most likely to deliver optimal efficacy and safety.

«We differentiate ourselves a lot in terms of our actual efficacy because it is a personalized approach rather than just somebody signing up and having work done, and that work not necessarily matching the person or their situation,» said John.