I've seen the potential for districts to gather local evidence on
the efficacy of their programs in this way through the Proving Ground project at the Center for Education Policy Research (CEPR) at Harvard University, where I am director.
As a leader in the field of social - emotional learning, we take part in international conferences focused on education policy and reform and collaborate with research organizations to study the viability and
efficacy of our programs in individual countries.
Not exact matches
Topics included: early reporting on inaccuracies
in the articles
of The New York Times's Judith Miller that built support for the invasion
of Iraq; the media campaign to destroy UN chief Kofi Annan and undermine confidence
in multilateral solutions; revelations by George Bush's biographer that as far back as 1999 then - presidential candidate Bush already spoke
of wanting to invade Iraq; the real reason Bush was grounded during his National Guard days — as recounted by the widow
of the pilot who replaced him; an article published throughout the world that highlighted the West's lack
of resolve to seriously pursue the genocidal fugitive Bosnian Serb leader Radovan Karadzic, responsible for the largest number
of European civilian deaths since World War II; several investigations
of allegations by former members concerning the practices
of Scientology; corruption
in the leadership
of the nation's largest police union; a well - connected humanitarian relief organization operating as a cover for unauthorized US covert intervention abroad; detailed evidence that a powerful congressional critic
of Bill Clinton and Al Gore for financial irregularities and personal improprieties had his own track record
of far more serious transgressions; a look at the practices and values
of top Democratic operative and the clients they represent when out
of power
in Washington; the murky international interests that fueled both George W. Bush's and Hillary Clinton's presidential campaigns; the
efficacy of various proposed solutions to the failed war on drugs; the poor - quality televised news
program for teens (with lots
of advertising) that has quietly seeped into many
of America's public schools; an early exploration
of deceptive practices by the credit card industry; a study
of ecosystem destruction
in Irian Jaya, one
of the world's last substantial rain forests.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European countries that may increase the amount
of discount required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability
of funding for state AIDS Drug Assistance
Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
Programs (ADAPs); continued fluctuations
in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory
programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; safety and
efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase
program due to changes
in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Most biotechs would have shuttered a clinical
program that showed absolutely no
efficacy whatsoever
in a late - stage trial, but Novavax has instead doubled down on RSV by going forth with its phase 3 trial
of the RSV F vaccine for infants via maternal immunization, and begun planning for another trial
in older adults that's reportedly on track to kick off
in 2018.
The award
program, created fifteen years ago, rewards and recognizes companies that are investing
in rigorous and measurable scientific studies to show the
efficacy of their proprietary ingredients, products or technologies.
I think this Salon article makes an interesting point
in exploring the
efficacy of bystander education
programs that target specific communities.
In the third trial
of the nurse home visitor
program, nurse - visited, 6 - month - old infants born to mothers with low psychological resources (i.e., maternal IQ, mental health, and sense
of efficacy) displayed fewer aberrant emotional expressions (e.g., low levels
of affect and lack
of social referencing
of mother) associated with child maltreatment.18
The brief includes the analysis
of survey data from
program participants on child safety
in the home, observed parenting practices, parental stress and parenting
efficacy, self - reported parenting practices, and rates
of child maltreatment.
Meta - analyses
of this expanded research base confirm the model's impacts on a range
of risk and protective factors associated with child maltreatment.7, 8,9
In addition, all of the major home visitation models in the U.S. are currently engaged in a variety of research activities, many of which are resulting in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parent
In addition, all
of the major home visitation models
in the U.S. are currently engaged in a variety of research activities, many of which are resulting in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parent
in the U.S. are currently engaged
in a variety of research activities, many of which are resulting in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parent
in a variety
of research activities, many
of which are resulting
in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parent
in better defined models and more rigorous attention to the key issue
of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up
of the Early Head Start National Demonstration Project confirm the
efficacy of home visitation
programs with new parents.
In addition to being influenced by the outcome
of interest, the
efficacy of home visiting
programs is dependent upon the population targeted, providers and home visit content.
In order to accurately measure the efficacy of several home visiting programs, a comprehensive assessment that includes measures of multiple child and family outcomes at various points in time should be favoure
In order to accurately measure the
efficacy of several home visiting
programs, a comprehensive assessment that includes measures
of multiple child and family outcomes at various points
in time should be favoure
in time should be favoured.
Personally I am not a fan
of these types
of structured
programs because 1) there is not adequate research to support their
efficacy and 2) they approach literacy development
in a highly contrived manner.
Meta - analyses
of studies evaluating these
programs show positive effects on the competence,
efficacy and psychological health
of the parents, as well as on the behaviour
of the children.49, 50 A recent implementation study
of a strategy for parenting and family support showed that families
in the treatment group had far fewer cases
of substantiated child maltreatment, abuse injuries and out -
of - home placements.51
In the teaching of research ethics, she initiated the Teaching Responsible Conduct of Research (TRCR) certificate program offered through the University of Illinois and done research on the efficacy of and developed materials in wide use, including experiential learning materials ranging from two - minute challenges for incorporation into substantive courses to role playing exercise
In the teaching
of research ethics, she initiated the Teaching Responsible Conduct
of Research (TRCR) certificate
program offered through the University
of Illinois and done research on the
efficacy of and developed materials
in wide use, including experiential learning materials ranging from two - minute challenges for incorporation into substantive courses to role playing exercise
in wide use, including experiential learning materials ranging from two - minute challenges for incorporation into substantive courses to role playing exercises.
Most studies evaluating the
efficacy of AA are not definitive; for the most part, they associate the duration
of participation with success
in quitting drinking but do not show that the
program caused that outcome.
And if it somehow did, Africa is much better equipped to deal with than it was
in the 1980s when chloroquine resistance hit, WHO experts say, with strong national malaria
programs in place and increased monitoring
of drug
efficacy.
The
program works by connecting computer - generated drug profiles — including mechanisms
of action, clinical
efficacy, and side effects — with information about how a molecule may interact with human proteins
in specific diseases, such as ovarian cancer.
During the past year alone, concerns about oversight
of high - containment laboratories; vetting
of personnel (personnel reliability); the
efficacy of security measures
in place for the select agent
program; medical countermeasure research, development and distribution; bioterrorism and pandemic influenza preparedness; misuse
of beneficial biological research and technologies; and microbial forensics have generated several policy evaluations and prompted the development
of policy recommendations and legislation.
Following a lapse
in such
programs, the findings also stress the importance
of including specific coping mechanisms and reinforcing a person's self -
efficacy,
in other words, bolstering their belief
in their own ability to reach their goals.
«We are at a point
in our research where we have validated the
efficacy of this combination treatment approach
in preclinical animal models, and we now need to define its safety through toxicology and pharmacology studies,» says Fisher, Thelma Newmeyer Corman Endowed Chair
in Cancer Research and co-leader
of the Cancer Molecular Genetics research
program at VCU Massey, chairman
of VCU School
of Medicine's Department
of Human and Molecular Genetics and director
of the VCU Institute
of Molecular Medicine.
The language
of program evaluators is framed
in terms
of efficacy: what is the actual outcome
of an intervention, compared with the outcome expected from no intervention?
According to Choe's research team, the current «attract - and - kill» approach, once it is successfully implemented
in practical pest management
programs, could potentially provide maximum control
efficacy with reduced amount
of insecticides applied
in the environment.
«While these results are encouraging, they represent a first step
in exploring the
efficacy of prospective memory training with the Virtual Week training
program,» said Dr. Craik.
Published
in the Journal
of Psychosocial Oncology, «Development and Initial Evaluation
of a Telephone - Delivered Behavioral Activation and Problem - solving Treatment
Program to Address Functional Goals
of Breast Cancer Survivors,» covers two studies looking at feasibility and potential
efficacy.
In the sensitive tumor models, the ability
of anti — cytotoxic T lymphocyte — associated protein 4 or anti —
programmed cell death 1 therapy to increase vessel perfusion strongly correlated with its antitumor
efficacy.
Modulation
of Gut Microbiota: A Novel Paradigm
of Enhancing the
Efficacy of Programmed Death - 1 and
Programmed Death Ligand - 1 Blockade Therapy — Yiming Wang — Frontiers
in Immunology
«The objective
of the Clinical Cell Therapy
Program is to develop new methods to regrow heart muscle and blood vessels, and evaluate the
efficacy of these methods as an approach to improving heart function
in patients with a variety
of heart disorders,» said Anthony DeMaria, M.D., director
of the Sulpizio Family Cardiovascular Center at UC San Diego.
Along with our nonprofit partners, this
program aims to collect, organize, and validate massive amounts
of data generated by clinical trials across our global trial network sites
in order to generate novel insights into biomarkers for safety and
efficacy, novel treatment strategies, and personalization
of treatment regimens.
«The ASGCT decision to include a presentation on AST - OPC1
in its Presidential Symposium signifies the ground - breaking nature
of our
program, and reflects the encouraging
efficacy and safety data we have seen to date
in patients with severe spinal cord injuries that have been treated with AST - OPC1,» commented Steve Cartt, President and Chief Executive Officer
of Asterias.
In the RV144 vaccine trial, led by the U.S. Military HIV Research
Program at the Walter Reed Army Institute
of Research, the
efficacy at 3.5 - years was 31.2 %; however, a higher early effect (60 %) was seen at 12 months.
Cherylynn Marino, Ph.D., a postdoctoral fellow, received $ 198,645 to examine the
efficacy of a mindfulness - based cognitive therapy (MBCT)
program in children and adolescents with TBI.
Immunologic checkpoint blockade with anti — cytotoxic T - lymphocyte — associated antigen 4 (CTLA - 4) or anti —
programmed death 1 (PD - 1) /
programmed death ligand 1 (PD - L1) agents seems to have some degree
of clinical
efficacy in advanced mucosal melanoma, although data are limited to smaller retrospective series or subset analyses
of prospective trials.
With our anti-TIGIT antibody
program, we saw anti-tumor
efficacy and reactivation
of T - cells
in preclinical models which is encouraging for the potential
of this product as a monotherapy
«This finding is consistent with a hypothesis generated out
of the follow - up studies to the RV144 HIV vaccine trial
in Thailand that showed the first
efficacy in humans,» noted COL Nelson Michael, Director
of the U.S. Military HIV Research
Program at the Walter Reed Army Institute
of Research.
Sanjay Gurunathan from Sanofi Pasteur, manufacturer
of one
of the vaccines used
in RV144, said a new partnership
of the US National Institute
of Allergy and Infectious Diseases, The Bill & Melinda Gates Foundation, HIV Vaccine Trials Network, US Military HIV Research
Program (MHRP), and Sanofi Pasteur — known as the Pox Protein Public Private Partnership, or P5 — will aim to increase vaccine
efficacy from the 31.2 percent
of the RV144 trial to 50 percent.
«ECHO - 203 is part
of the broader ECHO clinical development
program investigating
efficacy and safety
of epacadostat as a core component
of combination therapy
in a broad range
of solid tumor types as well as hematological malignancies,» said Naing.
Many
of the formulas we use
in the clinic have been around for over a thousand year and have a high degree
of clinical
efficacy The herbal formulas we use
in the anti-aging
program are classified as tonics
in Chinese medicine.
My Master's project looked at the
efficacy of a mindful eating - based diabetes prevention
program in a primarily Hispanic food pantry population.
In fact, the efficacy of the Atkins program has been documented in at least one other major study, featured in the JAMA (The Journal of the American Medical Association) in 200
In fact, the
efficacy of the Atkins
program has been documented
in at least one other major study, featured in the JAMA (The Journal of the American Medical Association) in 200
in at least one other major study, featured
in the JAMA (The Journal of the American Medical Association) in 200
in the JAMA (The Journal
of the American Medical Association)
in 200
in 2007.
In 2010, The University
of Texas MD Anderson Cancer Center received more than $ 4.5 million — one
of the largest yoga - related grants ever — from the National Institutes
of Health's National Cancer Institute to support an ongoing study
of the
efficacy of yoga as part
of a treatment
program for women with breast cancer.
At Parsley Health, we suggest that any supplementation be part
of a well designed, personalized
program executed
in coordination with a physician to assure appropriateness,
efficacy and, above all, safety.
Short - term safety, tolerability and
efficacy of a very low - calorie - ketogenic diet interventional weight loss
program versus hypocaloric diet
in patients with type 2 diabetes mellitus.
In episode 210, the hosts step into the debate between those that espouse the
efficacy of 12 - step
programs such as AA and those who assert that there is no proof that such
programs are any more effective than traditional medical help.
In Edutopia's integrated studies research review, discover seven key approaches in effective curriculum integration, get our specific recommendations on evidence - based practices and programs, learn about pitfalls to avoid, and dig into an annotated bibliography of studies supporting the efficacy of integrated studies practice
In Edutopia's integrated studies research review, discover seven key approaches
in effective curriculum integration, get our specific recommendations on evidence - based practices and programs, learn about pitfalls to avoid, and dig into an annotated bibliography of studies supporting the efficacy of integrated studies practice
in effective curriculum integration, get our specific recommendations on evidence - based practices and
programs, learn about pitfalls to avoid, and dig into an annotated bibliography
of studies supporting the
efficacy of integrated studies practices.
The
efficacy of running one - to - one
programs in schools is that, through this approach to technology education for students, teachers and families, schools are providing a laboratory
of trial and error and figuring out a way to make sense
of the fast - changing world
of technology.
It is worth pausing to dwell on this fact: there are virtually no data with which to evaluate the
efficacy of this
program, yet the
program has been embraced by two states and by the largest city
in the United States.
For instance, when evaluating the
efficacy of an online professional development
program, an evaluator may randomly select one group
of learners to participate
in an online
program.
In any case, no reputable researcher would rely on a one - year bump in some test scores to judge the efficacy of a new progra
In any case, no reputable researcher would rely on a one - year bump
in some test scores to judge the efficacy of a new progra
in some test scores to judge the
efficacy of a new
program.
Because
of this converging scientific consensus, the No Child Left Behind Act requires school districts to demonstrate that they are using reading
programs that have been tested for their
efficacy through scientific studies
in order to qualify for federal reading funds.