Her research involves preclinical immunology and
efficacy of vaccines against H5N1 pandemic influenza, malaria, and Mycobacterium tuberculosis using mouse, ferret and guinea pig models.
The efficacy of the vaccine against severe malaria in this same group was around 45 %.
Not exact matches
Together with researchers at the CNRS, the group has demonstrated the
efficacy of RNA - based
vaccines produced using the new method
against plant virus infections.
Unintended effects
of this process have reduced
vaccine efficacy against H3N2 the past two years, Deem said.
The study, «The
efficacy of the BCG
vaccine against newly emerging clinical strains
of Mycobacterium tuberculosis,» was published in the journal PLOS One in September.
«A particularly noteworthy accomplishment by the IVI has been the development
of a sublingually administered
vaccine which has demonstrated
efficacy in eliciting mucosal immunity
against respiratory and genital tract infections,» he notes.
One
of the
vaccines, which is based on a recombinant vesicular stomatitis virus expressing the glycoprotein
of the Zaire strain
of the Ebola virus (VSV - ZEBOV), was recently shown to be extremely effective with 100 per cent
efficacy against the lethal Ebola virus disease in WHO - funded studies carried out in Guinea and Sierra Leone.
«Although data clearly indicate better immune responses and
vaccine efficacy against both genital warts and cervical dysplasia when vaccination occurs before age 14, this study suggests that HPV vaccination may be effective in reducing abnormal Pap test results even after sexual debut,» explained co-author Rebecca Perkins, MD, MSc, assistant professor
of Obstetrics and Gynecology at Boston University School
of Medicine and a gynecologist at Boston Medical Center.
Janda and his coworkers reported in a paper in the Journal
of the American Chemical Society in June the successful synthesis
of a
vaccine against heroin that showed
efficacy in monkeys.
Efficacy against malaria infection
of PfSPZ
Vaccine administered to infants 5 - 12 months of age in 3 doses by passive and active surveillance for naturally acquired Pf infection, measured by blood smear microscopy, during 6 months following the last vaccin
Vaccine administered to infants 5 - 12 months
of age in 3 doses by passive and active surveillance for naturally acquired Pf infection, measured by blood smear microscopy, during 6 months following the last
vaccinevaccine dose.
The study, «The
efficacy of the BCG
vaccine against newly emerging clinical strains
of Mycobacterium tuberculosis,» was published in September.
A new paper published in the Journal
of Allergy and Clinical Immunology has reported on a multicentre trial to test the safety and clinical
efficacy of a new
vaccine against grass pollen allergy in patients with grass pollen — induced rhinitis and controlled asthma.
Protective
efficacy of multiple
vaccine platforms
against Zika virus challenge in rhesus monkeys.
The World Health Organisation has announced that a phase III trial
of the VSV - EBOV
vaccine will begin in Guinea on the 7th March, to test its
efficacy against Ebola.
Correlates
of Protection
against Influenza in the Elderly: Results from an Influenza
Vaccine Efficacy Trial.
However, until an AMA1 malaria
vaccine demonstrates clinical
efficacy against genetically diverse natural parasites, the relevance
of growth inhibition assays and other humoral and cellular immunogenicity endpoints for clinical development decisions will remain a matter
of reasoned conjecture.
A research article published in the journal Science has reported the
efficacy of three different
vaccine platforms
against the Zika virus in rhesus macaque monkeys.
The findings were published In the New England Journal
of Medicine (NEJM) and concluded that
vaccines designed to induce higher levels
of V1V2 antibodies and lower Env - specifc IgA antibodies could result in improved
efficacy against HIV - 1 infection.
At the first plenary session
of AIDS
Vaccine 2011, which opened this morning in Bangkok, Thailand, researchers presented the results of a two - year - long effort to try to identify an immunological explanation for the modest 31 % efficacy afforded by the prime - boost vaccine regimen tested in the RV144 trial, the first to show any efficacy in protecting against HIV inf
Vaccine 2011, which opened this morning in Bangkok, Thailand, researchers presented the results
of a two - year - long effort to try to identify an immunological explanation for the modest 31 %
efficacy afforded by the prime - boost
vaccine regimen tested in the RV144 trial, the first to show any efficacy in protecting against HIV inf
vaccine regimen tested in the RV144 trial, the first to show any
efficacy in protecting
against HIV infection.
The same year, the FDA approved the start
of the first human clinical trial
of this
vaccine that demonstrated its safety and
efficacy at inducing an immune response
against the virus.
Model A: Adjuvanted
vaccines head to head comparison Model B: Mouse model for protective
efficacy against clinical (Beijing) strains
of M.tb.
«Now you have a way to test
efficacy of future
vaccines or future therapeutics, whether those therapeutics are drugs that exist already that could be used in a different way for a different purpose, or new classes
of drugs such as antibody - based therapeutics that would be more specifically
against Zika,» Diamond said.
These
vaccine candidates warrant further clinical evaluation
of efficacy against the blood - stage P. vivax parasite.
Current topics include
vaccine efficacy testing and immune correlates
of TB, AMA1 as a malaria blood stage
vaccine candidate in clinical development and development
of new drugs active
against malaria hypnozoites.
The researchers say that the
efficacy of the
vaccine was «high,» but mostly in terms
of protecting
against infection — not cervical cancer.
Introducing VANGUARD ® CIV H3N2 / H3N8, a bivalent canine flu
vaccine with demonstrated safety and
efficacy for protection
against both highly contagious H3N2 and H3N8 strains
of canine influenza virus (CIV).
After all, the best way to help protect horses
against EIV is to vaccinate before exposure to this highly contagious respiratory disease.8 And that's why horse owners can depend on the FLUVAC INNOVATOR
vaccine line, because it helps offer demonstrated protection
against EIV and is backed by the Zoetis commitment to continuously monitor and evaluate the
efficacy and safety
of its products.
Although a
vaccine aimed at protecting
against FIP exists, Dr. Scott notes that its
efficacy has proved to be
of dubious value.
I would consider vaccination
against Bordetella optional, personally — because it is going to be real pain if you insist that it be done correctly and because the
efficacy of the
vaccine is thought to be moderate.
Scientists have looked at the
efficacy of several other intramuscular
vaccines in dogs to see its effect in protecting
against canine kennel cough (9).