Sentences with phrase «efficacy profile of»

There is no question in our confidence in the safety and efficacy profile of BRAVECTO ®.

«The safety and efficacy profile of acetaminophen is supported by more than 150 studies over the past 50 years,» the company added.

Not exact matches

«This investigational single tablet regimen brings together the potency of an integrase inhibitor, bictegravir, with the demonstrated efficacy and safety profile of the FTC / TAF backbone,» said Norbert Bischofberger, executive vice president, research and development and chief scientific officer, Gilead Sciences.

As the only two - dose hepatitis B vaccine for adults that also sports a superior efficacy profile to GlaxoSmithKline's Engerix - B, Dynavax should be able to easily gobble up the lion's share of this market moving forward.

«Until we have further evidence on the efficacy of medical cannabis for the treatment of sleep apnea, and until its safety profile is established, patients should discuss proven treatment options with a licensed medical provider at an accredited sleep facility,» said lead author Dr. Kannan Ramar, professor of medicine in the division of pulmonary and critical care medicine at Mayo Clinic in Rochester, Minnesota.

The program works by connecting computer - generated drug profiles — including mechanisms of action, clinical efficacy, and side effects — with information about how a molecule may interact with human proteins in specific diseases, such as ovarian cancer.

«Results described in this manuscript provide a comprehensive characterization of the efficacy of the PMO antisense platform against Marburg virus in nonhuman primates and its safety profile in humans,» Bavari said.

Pharmacogenomics — the study of how genes affect responses to drugs — is becoming more important in drug - development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.

We also develop in silico chemogenomic approaches to analyze jointly the chemical space of small molecules and biological space of protein targets, leading in particular to efficacy profile and secondary effect prediction.

Based on proof - of - concept pre-clinical studies indicating robust efficacy and favorable safety profile, the company is now advancing to conduct a clinical trial testing the efficacy of this new treatment.

SB models will allow the analysis of such correlations to identify cytokine profiles predictive of efficacy and safety.

The TPP criteria could include the target population, specific number of doses, a certain percentage of efficacy and a clear safety profile.

Although these studies were limited to small patient numbers, given the rarity of this disease, PD - 1 pathway blockade seems to have clinical efficacy in mucosal melanoma, with a tolerable safety profile.

Given the rather divergent toxicology and adverse event profiles seen with bardoxolone and DMF, we conclude that induction of Nrf2 can be advantageous, but that the electrophilic character of the molecule is crucial and thus sets significant limitations on the safety and efficacy of such compounds.

Particularly in the area of neurodegeneration, attention has been drawn to repurposing existing drugs with proven efficacy and safety profiles.

Despite the expansion of genetic profiling, there remains a large percentage of patients for whom no biomarkers of drug efficacy are detected or who become refractory to their targeted therapy or chemotherapy regimen.

Importantly, IMGN632 was effective at concentrations well below those that affected normal bone marrow cells, suggesting the potential for efficacy in AML patients with reduced likelihood of myelosuppressive side effects and favorable safety profile.

Some of these suggestions or advice includes the creation of an efficacy profile, where you can describe yourself and your perfect day.

Jessica Quimby, DVM, leader of the CSU research, said the current undertaking is designed to further test the efficacy of the treatment now that previous research at the school has established a strong safety profile.

A paper reporting a «rigorous double blind» study — the VIGOR trial — was submitted to NEJM in 1998, got through peer review at one of the most up - tight journals in the world of medicine, and — by way of cherry - picking the data submitted (selecting out some study subjects whose adverse events histories which, if considered, would've significantly affected the safety profile for rofecoxib and revealed something that Merck really didn't want us prescribers to learn about their «blockbuster» product — was published to be touted by Merck's marketing weevils as solid proofs of Vioxx's tolerability, efficacy, and safety.

A researcher might work in testing the efficacy of a new medicine, designing engineering programs, creating a historical profile or assisting students or teachers in researching information for term papers, articles or journal publications.