Sentences with phrase «efficacy study in»

The first clinical trial was a safety study in Australia, followed by an ongoing efficacy study in Peru to evaluate the ability to treat patients with malaria.

We hope to move from the safety study into a full scale efficacy study in the spring, involving more patients in centres around the UK and Europe.

They are planning to pursue a Phase 1 safety and efficacy study in human volunteers.

This result implies that only large treatment effects can be detected by efficacy studies in hAPP mice, since the number of mice per group will likely not be greater than 50, for practical and ethical reasons.

We produce live and inactivated viruses in our BSL2 and BSL3 facilities, and perform immunogenicity and efficacy studies in pigs (influenza) and sheep (RSV) with a focus on skin vaccination and extended monitoring of humoral and cellular immune responses in the blood and lung.

In the ensuing months, the two companies have published detailed, promising animal studies of their immunotherapies, including preclinical efficacy studies in animal models of human synucleinopathies.

Immunogenicity and efficacy studies in pig (influenza) and sheep (RSV) with a focus on skin vaccination and extended monitoring of humoral and cellular immune responses in the blood and lung.

PFIE will provide access to its facilities for immunogenicity and efficacy studies in pigs or sheep (as well as other species if needed), according to users» requirements.

In this brief, we present evidence from the first of our textbook efficacy studies in California.

Not exact matches

Topics included: early reporting on inaccuracies in the articles of The New York Times's Judith Miller that built support for the invasion of Iraq; the media campaign to destroy UN chief Kofi Annan and undermine confidence in multilateral solutions; revelations by George Bush's biographer that as far back as 1999 then - presidential candidate Bush already spoke of wanting to invade Iraq; the real reason Bush was grounded during his National Guard days — as recounted by the widow of the pilot who replaced him; an article published throughout the world that highlighted the West's lack of resolve to seriously pursue the genocidal fugitive Bosnian Serb leader Radovan Karadzic, responsible for the largest number of European civilian deaths since World War II; several investigations of allegations by former members concerning the practices of Scientology; corruption in the leadership of the nation's largest police union; a well - connected humanitarian relief organization operating as a cover for unauthorized US covert intervention abroad; detailed evidence that a powerful congressional critic of Bill Clinton and Al Gore for financial irregularities and personal improprieties had his own track record of far more serious transgressions; a look at the practices and values of top Democratic operative and the clients they represent when out of power in Washington; the murky international interests that fueled both George W. Bush's and Hillary Clinton's presidential campaigns; the efficacy of various proposed solutions to the failed war on drugs; the poor - quality televised news program for teens (with lots of advertising) that has quietly seeped into many of America's public schools; an early exploration of deceptive practices by the credit card industry; a study of ecosystem destruction in Irian Jaya, one of the world's last substantial rain forests.

People are less likely to be dissatisfied with market volatility if they feel in control of their financial life, according to a study published last month in the Journal of Behavioral Science, entitled, Market Volatility and Financial Satisfaction: The Role of Financial Self - Efficacy.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Other studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator in patients with brain cancer (as seen by increased uptake of the amino acid on a PET scan).

In a study of CMOs, nearly a third of respondents said the «black box» nature of many analytical tools, which makes it difficult for marketers to understand the results they generate, were a primary limitation on their marketing efficacy.

Detailed 48 - week results from a Phase 3 study evaluating the efficacy and safety of switching from a regimen containing abacavir, dolutegravir and lamivudine (600 / 50/300 mg)(ABC / DTG / 3TC) to Biktarvy, a once - daily single tablet regimen, in virologically suppressed adults with HIV.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«What is not clear to us is whether the low yield of eggs was the culprit in the lack of a robust efficacy signal» in the Phase 1 study, he explained.

This webinar follows up on iAcquire's 2011 Quantifying Outreach study wherein they analyzed 300,000 outreach emails to determine what techniques yield the highest efficacy for outreach in link building.

While ANB020 has Dupixent beat in terms of convenience, we really can't make an apples - to - apples efficacy comparison without a head - to - head study.

34 As would be expected, these studies are following those lines that must be considered if room is made for a strong sense of the significance of preaching: church and Scripture in preaching, the faith and character of the priest and the efficacy of preaching.

The group also cited that the application for Direct Use would subject unknowing communities to feeding studies in order to ascertain efficacy of Golden Rice.

NDI1 a producer in N.D., USA of organic ~ flax hull lignans ~ has documented studies related to efficacy against several types of cancer.

Most of the homemade remedies are supported by a study providing evidence in favor of their efficacy, but we can not guarantee that a certain recipe would help you in treating any other similar health condition.

After obtaining the necessary permits and approvals, an independent community nutrition study will be conducted to evaluate the efficacy of Golden Rice; in other words, whether or not it improves vitamin A status.

The title of the study is A Pilot Study: The Efficacy of Virgin Coconut Oil as Ocular Rewetting Agent on Rabbit Eyes and was published in the journal Evidence - based Complementary and Alternative Medicine, February, study is A Pilot Study: The Efficacy of Virgin Coconut Oil as Ocular Rewetting Agent on Rabbit Eyes and was published in the journal Evidence - based Complementary and Alternative Medicine, February, Study: The Efficacy of Virgin Coconut Oil as Ocular Rewetting Agent on Rabbit Eyes and was published in the journal Evidence - based Complementary and Alternative Medicine, February, 2015.

The studies were not intended to address questions related to the efficacy of GR2E Golden Rice in helping to address vitamin A deficiency in affected population sub-groups, which can only be adequately addressed following regulatory authorization.

[1] Lugo JP, et al. «Efficacy and tolerability of an undenatured type ll collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double - blind, placebo - controlled study.»

However, the efficacy of carotenoid - rich foods in the prevention of vitamin A deficiency has been questioned in several recent studies, which reported little or no nutritional benefit of vitamin A from the increased consumption of dark - green or yellow vegetables (11, 12).

The award program, created fifteen years ago, rewards and recognizes companies that are investing in rigorous and measurable scientific studies to show the efficacy of their proprietary ingredients, products or technologies.

Although caffeine is the most common stimulant in these drinks, many other stimulants are used without any studies to support their efficacy or safety.

A recent analysis of the Longitudinal Study of Australian Children (LSAC) found that, in fathers, a higher parenting self - efficacy score was related to lower work - family strain; and a key mechanism by which fathers» work / family strain was decreased was by their doing more than they regarded as their «fair share» of child rearing tasks.

A Dutch study found that among the 65 % of mothers who prevented passive smoking to some extent, success was linked with the mother's self - efficacy in asking others not to smoke (Crone et al, 2001).

Whilst there are no RCT studies available at this time to draw definitive conclusions about the efficacy of this process, many clinical reports exist to indicate that placenta encapsulation is helpful in the postpartum period in terms of increasing milk supply (acting as a galactagogue) and improving mood in the postpartum period.

They have a vested interest in publishing studies that promote the use of their medications and failing to publish study results that call the efficacy or safety of their drugs into question.

In 2001, a Swiss study was conducted to investigate the efficacy of using compression stockings during pregnancy as a method of preventing varicose veins.

Sensory Integration (SI) is somewhat of an unknown in the medical arena, and understandably so — it is just recently that studies are beginning to demonstrate the true efficacy of treatment.

Mothers reported more symptoms of psychological distress24, 25 and low self - efficacy.26, 27 And, although mothers report more depressive symptoms at the time their infants are experiencing colic, 28,29 research on maternal depression 3 months after the remittance of infant colic is mixed.30, 31 The distress mothers of colic infants report may arise out of their difficulties in soothing their infants as well as within their everyday dyadic interactions.32 The few studies to date that have examined the long - term consequences of having a colicky child, however, indicate that there are no negative outcomes for parent behaviour and, importantly, for the parent - child relationship.

In the early 1930s the number of studies on introducing solids to infants increased significantly, and the use and efficacy of commercially prepared canned baby food was integral to this research and the debate.

The randomized study, working with 1,345 third to fifth graders (8 - 11 year olds) in nine US elementary schools, assessed the efficacy of a three - year programme.

Meta - analyses of studies evaluating these programs show positive effects on the competence, efficacy and psychological health of the parents, as well as on the behaviour of the children.49, 50 A recent implementation study of a strategy for parenting and family support showed that families in the treatment group had far fewer cases of substantiated child maltreatment, abuse injuries and out - of - home placements.51

Although professional lactation support can improve the duration of overall breast feeding, its effect in improving exclusive breast feeding is unclear.11 18 22 Thus far, studies that report improvement of rates of exclusive breastfeeding have involved mainly community based peer counselling strategies.23 24 25 Even then, a randomised trial in the UK recently cast doubt on the efficacy of this approach.26 There are current recommendations from NICE for the UK - wide implementation of the baby friendly initiative.4 5 6 The 2006 NICE costing report on routine postnatal care of women and their babies estimates that efforts to improve rates of breast feeding will result in substantial cost savings for the NHS.6

Summary: This study, published in the American Journal of Clinical Nutrition in November 2009, investigated the efficacy of multivitamin supplements at single...

Effects of a mindfulness - based intervention on psychological distress, well - being, and maternal self - efficacy in breast - feeding mothers: results of a pilot study

BY NATHAN RILEY Outraged that Mayor Bill de Blasio continues to sit on a city health department study into the efficacy of establishing safe places for drug users to pursue their high — facilities that are in place all over Europe with proven track records of reducing fatal overdoses — protestors sat down in the middle of Broadway across from City Hall bringing downtown traffic to a halt.

Other studies have shown cannabinoids» efficacy in relieving pain and reducing anxiety and sleeplessness in cancer and AIDS sufferers.

The study is the first to examine preschool teachers» «self - efficacy» — or their belief in their ability and enjoyment for an academic area — in literacy, math and science.

In the new study, the method accurately predicted vaccine efficacy rates for more than 40 years of flu records.

Further studies in animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.

Thomas Smith, who studies the epidemiology of malaria at the Swiss Tropical Institute in Basel, says it may be premature to say exactly what the efficacy is based on this early data from the trial, which is still ongoing.

The study, «The efficacy of the BCG vaccine against newly emerging clinical strains of Mycobacterium tuberculosis,» was published in the journal PLOS One in September.