Sentences with phrase «efficient gene delivery»
The advent of molecular cloning, DNA sequencing and the many tools of molecular genetics and cell biology has given us sufficient knowledge of the basis for disease and the genes to target, but what has limited the application of gene therapy has been efficient gene delivery systems.
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Initial tests on mice showed the hybrid virus was very efficient: the gene it carried was active in 24 per cent of airway cells after two months, a far better proportion than achieved by other delivery methods (New Scientist, 10 March 2001, p 19).
American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.
Perhaps, a molecule that could stimulate neurotrophic factors, such as NGF in vivo, would be more efficient, more safe and cost effective than gene delivery directly into the brain.
We have established a safe and efficient method of inducing transient (removable) pluripotency based upon state - of - the - art transposon - based gene delivery vectors.