Sentences with phrase «efficient models of disease»

Not exact matches

Mardinoglu says the team's network modeling approach, which relied on data from the Sweden - based Human Protein Atlas project and The Genotype - Tissue Expression (GTEx) project consortia, can be used in the identification of drug targets and eventually in the development of efficient strategies for treating a number of chronic liver diseases.

In order to an early detection or a correct medication of potentially chronic diseases, we need more efficient models in the primary health care to identify those who are at risk.

Many of these devices resemble sleeker, more efficient models of instrumentation used by research labs to record brain activity during sleep, physiological changes during stress, migraine triggers, activity levels and even early symptoms of debilitating neurological diseases.

Furthermore, new genome - editing technologies such as CRISPR / Cas9 now enable the efficient derivation of precision disease models incorporating patient - specific genetic variants as a means of recapitulating essential aspects of human disease in mouse and other model organisms.

The efficient genome editing shown here demonstrates that these pigs can serve as a powerful tool for dissecting in vivo gene functions and biological processes in a temporal manner and for streamlining the production of genome - edited pigs for disease modeling.

By developing a simple chemically defined culture system permitting efficient differentiation of numerous human iPS cell lines toward cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin whose phenotypes are a consequence of complex protein dysregulation within adult cells.

Efficient effective integrated systems are needed to reduce the impact of increasing chronic disease and an aging population and these concepts can be applied for long - term models.