Sentences with phrase «efflux antibiotics»

Not exact matches

Bacteria that use these «efflux pumps» and that are treated with the new compound become sensitive to antibiotics they were previously resistant to.

Bacterial efflux pumps, such as the P. aeruginosa MexAB - OprM pump shown here, are one of the dominant molecular mechanisms available to Gram - negative pathogens for removing toxins, including antibiotics.

«We study a lot of efflux pumps to understand antibiotic resistance,» said Yu, an Iowa State professor with appointments in physics and astronomy; chemistry; biochemistry, biophysics and molecular biology; and the U.S. Department of Energy's Ames Laboratory.

New supercomputer simulations have revealed the role of transport proteins called efflux pumps in creating drug - resistance in bacteria, research that could lead to improving the drugs» effectiveness against life - threatening diseases and restoring the efficacy of defunct antibiotics.

One trick used by some bacteria is to eject antibiotics through so - called efflux pumps embedded in their cellular membranes.

Some coded for multi-drug efflux pumps, which are multi-drug resistance mechanisms embedded in the bacterial membrane that pump specific antibiotics out of the bacteria.

Heterogeneity in a bacterial population that arises through a mechanism of biased partitioning of drug efflux pumps, as we identified in our study, could be a stepping - stone on the path of bacterial populations towards antibiotic resistance.»

The researchers found four new chemicals that seek out and disrupt bacterial proteins called «efflux pumps,» known to be a major cause of antibiotic resistance.

They plan to leverage a recently awarded Innovative and Novel Computational Impact on Theory and Experiment (INCITE) allocation from DOE to perform larger simulations on the Titan supercomputer to gain deeper understanding of how bacterial efflux pumps function, identify more potent efflux pump inhibitors and optimize the best antibiotic - plus - inhibitor combinations to make them suitable for clinical trials.

For those that are not having significant changes by 3 months then I am adding Biocidin to remove biofilms and to decrease antibiotic resistance by blocking efflux pumps that remove antibiotics from germs.

decreases drug resistance in Lyme by blocking efflux pumps that remove antibiotics from germs,

Based on unpublished lab experiments Biocidin breaks down biofilms and decreases antibiotic resistance by blocking efflux pumps that remove antibiotics from germs.

Germs in biofilms use efflux pumps that flush antibiotics out.

The hole in the canoe is the antimicrobial or the antibiotics coming in, and then, the efflux pumps are bailing that water out.