When female animals form egg cells inside their ovaries, they deposit messenger RNAs (mRNAs)-- a sort of genetic instruction set — in
the egg cell cytoplasm.
This hypothesis underestimates the opposing power of
the egg cell cytoplasm to reprogram the genes in the donor - cell nucleus.
Not exact matches
It is far more likely, however, that the
egg -
cell cytoplasm with its stripping factor will reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.
The second biological objection is that «the
egg -
cell cytoplasm» will «reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.»
For instance, the
egg -
cell cytoplasm strips off all of the many epigenetic factors which differentiate a genetically restricted donor skin
cell from a totipotent zygote.
Infertility treatments once considered revolutionary are now commonplace: If a man has a low sperm count, sperm
cells can be retrieved from a testicle for direct injection into an
egg's
cytoplasm.
Doctors take the
cytoplasm of a youthful and healthy
egg — containing not the dna but the proteins and enzymes for healthy
cell growth — and inject it into the problematic
egg to boost its quality.
In a healthy
egg Oskar initiates the formation of what's known as the germ plasm — a gathering of proteins and RNAs within the
cytoplasm, which then goes on to form a new germ
cell.
There on the screen was the huge, rotund universe of the female
egg cell, its internal jelly, or
cytoplasm, smooth and evenly grained, and there, just below the equator, two ghostly yolklike circles around the male and female DNA, mere mirages of genetic material, in close proximity, nearly nuzzling.
The female
egg cell is a huge biochemical universe unto itself, with a complex and sophisticated
cytoplasm.
When a sperm
cell meets an
egg cell (the oocyte), it burrows through the thick outer rind surrounding the
egg (the zona pellucida), enters the internal
cytoplasm of the
egg (the ooplasm), and locomotes its male DNA — half of the typical number of chromosomes — to the female half within about three to four hours.
Nucleoli (dark spots indicated by arrowheads, top) disappear in the presence of
egg -
cell cytoplasm (bottom).
The resulting embryos can grow up to be healthy adults, indicating that something in the
egg's
cytoplasm must prompt the nucleus to reverse the biochemical events that turned it into a specialized adult
cell.
Xi says part of the trick is to suck a minuscule amount of
cytoplasm out of
egg cells first to make room for the injected bacteria and prevent
cells from bursting.