Sentences with phrase «egg cell donors»

Farm raised dogs were frequently used as surrogates and egg cell donors as that industry came into existence — not to produce meat, but to allow bereaved pet owners to get laboratory - made duplicates of their dogs.

We have proposed simultaneous experiments to optimize the process of cloning Black - footed Ferrets using domestic ferrets as surrogate egg cell donors and mothers, thus avoiding using endangered Black - footed Ferrets for experimental procedures.

Not exact matches

It is far more likely, however, that the egg - cell cytoplasm with its stripping factor will reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.

OAR proponents claim that when the altered donor - cell nucleus with its activated nanog gene is transferred to the enucleated oocyte (egg cell), the presence of nanog will immediately convert the enucleated egg cell to a pluripotent cell, without ever forming a zygote.

The second biological objection is that «the egg - cell cytoplasm» will «reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.»

For instance, the egg - cell cytoplasm strips off all of the many epigenetic factors which differentiate a genetically restricted donor skin cell from a totipotent zygote.

This hypothesis underestimates the opposing power of the egg cell cytoplasm to reprogram the genes in the donor - cell nucleus.

In this process, the nucleus of a donor adult cell is transferred to an egg whose nucleus, and thus its genetic material, has been removed.

Both involve a technique called nuclear transplantation — replacing the nucleus of a donor's egg with the DNA from an adult cell.

One donor gave eight eggs, of which four yielded colonies of hESCs, suggesting several colonies could be made from each set of donated eggs (Cell, DOI: 10.1016 / j.cell.2013.05.006).

Combining an egg's genetic leftovers with donor cells may be a way to double the number of eggs available for IVF in women whose ovarian reserve is running low

They want to explore whether mitochondria from younger donors» cells may stimulate the older eggs» ability to be fertilized and develop normally.

«Before we get too excited about this being a new form of infertility treatment, these cells can not as yet be made into functioning sperm, so we have no idea if they can pass «the acid test» — the ability to fertilise female eggs as is achieved with donor sperm in IVF treatment,» says Malcolm Alison of the London School of Medicine and Dentistry in the UK.

OHSU scientists have also demonstrated that SCNT allows replacement of mutated mitochondrial genes with healthy donor egg mitochondria while retaining the patient cell's nucleus.

In theory, new embryos then could be created by combining converted egg or sperm cells with natural ones, or by combining eggs with sperm cells derived from different donor animals.

McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or chimeric animals to see how human stem cells behave during development.

Scientists had suggested that it might one day be possible to circumvent the shortage of donor eggs from adult women by developing ways of maturing undeveloped egg cells from a fetus in the laboratory (This Week, 15 January).

The scientists removed the DNA - containing nuclei from the eggs and replaced them with DNA from the donor skin cells.

In May 2006, Eggan's lab received approval from Harvard to seek healthy human eggs from female donors, a first step toward using research cloning to create new stem cell lines.

But the next step — transferring the nucleus — was different; rather than fusing the donor cell with the enucleated egg cell, the team removed the donor nucleus with a very fine needle and injected it into the donor egg.

The PPL team used the traditional fusion technique to marry the donor cell nucleus to the egg.

A year after receiving approval to study cloning in human cells, «we have yet to find a woman who's willing to participate as an egg donor,» he says.

Scientists can replace the mitochondria of the mother's egg cell with mitochondria from a healthy donor.

He tested various methods to quickly and precisely remove the nuclear materials from the egg cell and promote the fusion of the nucleus - donor cell and enucleated egg.

Like Dolly's creators in Scotland, Don Wolf of Portland's Oregon Health Sciences University and his colleagues transferred the nuclei from donor cells to eggs whose own DNA had been removed.

In addition, the sources of the replacement nuclei were the egg donors» own cumulus cells, which encircle developing eggs in the ovary.

When the team split this cell line into different dishes, sometimes the donor egg's mtDNA won out; but in others, the carried - over mtDNA dominated.

He points out that the extra eggs also have donor DNA in their mitochondria — small bodies that generate power for the cell.

The new finding brings a measure of closure to a story that first rocked the science world in February 2004, when Hwang and colleagues at Seoul National University announced they had cloned a female donor's cell by transferring its nucleus into one of her egg cells stripped of its nucleus in a procedure known as somatic cell nuclear transfer (SCNT), and harvested embryonic stem cells from the resulting fusion.

Because the egg - donor mother also supplies to each embryo a small number of mitochondria — tiny energy factories within cells that have some of their own genetic material — this approach even affords lesbian couples an approximation of sexual reproduction.

Dolly was created using nuclear transfer, a technique in which an intact donor cell is fused with an egg whose nucleus had been removed.

You inject the nucleus from Archie's cell into the donor egg.

Animal cloning uses a process known as somatic - cell nuclear transfer, where the nucleus from an adult (donor) cell is transferred into an egg (host) cell lacking a nucleus.

In order for all of the clones to have been exact copies of each other, the egg cells would have had to have come from the same female donor.

In a world - wide first, Chinese scientists cloned two monkeys by transplanting donor cells into eggs, they said on Wednesday, a feat that could lead to genetically engineered primates for drug testing, gene editing and brain research.

Hirano, Egli and colleagues have shown that in unusual cases, stem cell clones derived from MR eggs can show substantial drift towards the donors mtDNA haplotype after low level mtDNA carryover during the MR procedure.

After an extended number of cell divisions, random segregation of mitochondria may lead to cells containing a majority of mitochondria from the donor egg.

The second method used somatic cell nuclear transfer (cloning techniques) to exchange all the mtDNA from the patient's cells with normal mtDNA from an egg donor in order to derive embryonic stem cells that are patient - specific with respect to nuclear DNA, but «rescued» with respect to mtDNA.

In essence, these studies suggested that a newly fertilized, enucleated egg has the ability to «reprogram» a much older donor nucleus, making the resultant cell behave as though it were at a very early embryonic state.

The next steps in cloning would be to 1) insert a donor nucleus of a new bird into the enucleated egg cell, 2) stimulate embryonic growth, and 3) implant the embryo into a mother bird or egg.

An adult cell from the mammary gland of a Finn - Dorset ewe acted as the nuclear donor; it was fused with an enucleated egg from a Scottish Blackface ewe, which acted as the cytoplasmic (or egg) donor.

In the case of the human - cow embryo, the «donor egg» is the cow's egg, and the «patient's cell» could be something like a skin cell.

The chimeras then foster the sperm / eggs of the germ - cell donor, meaning when bred they will lay eggs and brood offspring of the donor.

This method transfers less donor mitochondria than other methods, often less than 1 percent of the total in the donor egg cell, Mitalipov said in a Tuesday conference call.

Our writer investigates the benefits of using skin care products that contain plant - derived stem cells — and non-embryonic human cells extracted from consenting egg donors (seriously).

In the process, the donor cells are merged with egg cells extracted from other dogs, zapped with an electrical current to spur splitting, then implanted in more dogs who serve as surrogates, carrying the embryos to pregnancy.

You can also use sperm and / or eggs from a donor if a problem with your own sperm cells or eggs is causing infertility issues.

In a lab, your eggs are mixed with sperm cells from your partner or a donor — this is called insemination.