This particular enzyme produces arachidonic acids from the membrane, which is then transformed into prostaglandins, plus other compounds known as
eicosanoids which have a contributing role in the degradative processes.
Not exact matches
Polyunsaturated fats (
which include Omega - 3s, like fish oil, and Omega - 6s) convert to
eicosanoids in the body.
It inhibits the production of
eicosanoids,
which are one of the precursors in the body's signaling pathway for inflammation.
Compared to dietary omega - 6 fatty acids,
which generally give rise to more inflammatory thromboxanes, prostaglandins, and leukotrienes, omega - 3 fatty acids are metabolized into less inflammatory
eicosanoid signaling molecules.
At a mechanistic level, curcumin mitigates inflammation by inhibiting an array of pro-inflammatory signaling molecules, such as the
eicosanoids known as leukotrienes, thromboxanes, and prostaglandins,
which elicit deleterious effects ranging from pain to blood clotting to airway constriction (Chainani, 2003).
This competition effect is troubling because among the many uses the body has for omega - 3s and -6 s, it converts them to signaling molecules called
eicosanoids,
which promote unhealthy amounts inflammation, blood coagulation, and blood vessel constriction.