Sentences with phrase «ejection fraction»

His team is now studying patients who have especially high risk of heart failure with preserved ejection fraction (HFpEF).

Omecamtiv mecarbil is a selective, small - molecule currently being studied in a Phase 3 clinical trial of ~ 8000 patients as a potential treatment for heart failure with reduced ejection fraction in collaboration with Amgen and in partnership with Servier.

A transthoracic echocardiogram demonstrated an inferior wall motion abnormality and a left ventricular ejection fraction of 35 - 45 % (see Figures 2 - 6).

We've gotten our nice randomized study in very sick congestive heart failure patients with low ejection fractions is the V - 4 engine are probiotic use it was actually saccharomyces boulardii and it wasn't that much, about three million.

The study categorized the patients by three distinct ejection fraction subgroups: normal, borderline and reduced.

This is the first study to use national data to specifically categorize heart failure by three distinct ejection fraction subgroups.

Exclusion criteria were congestive heart failure with a cardiac ejection fraction of < 30 %, malignancies, chronic kidney disease with a glomerular filtration rate of < 30 ml / min, severe cardiac arrhythmias, and inflammation (C - reactive protein > 5 mg / l).

Those taking Pycnogenol and Ubiquinol significantly increased their heart ejection fraction by 22.4 percent.

Ejection fraction [pumping ability] was 10 percent.

Doctors use ejection fraction to guide treatment of heart failure patients and estimate their likelihood of re-hospitalization and survival.

They are also more likely to develop myocardial dilatation, whereas women tend to develop hypertrophic cardiomyopathy with diastolic heart failure and preserved ejection fraction more often (305).

Displaying a similar dose - dependent trend, starting from an average of 34 percent, ejection fraction increased 4.9 percent in controls, 3.1 percent in the group receiving less than 14 million cells, 5.8 percent in the group receiving more than 14 million cells, and 10.2 percent in the group receiving more than 20 million cells.

The average starting ejection fraction was 34 percent, a sign of severe injury to the heart.

There are several published studies on Heart Failure patients from mild to severe that see improvement in life expectancy, quality of life, and also improved ejection fraction output.

About eight weeks later they documented ejection fractions going up, walking distance improving, symptoms ameliorating.

He also has a high percentage of stenosis and lower than normal ejection fraction, all signs pointing to a serious heart condition.

These rates apply for aortic and mitral valve repairs with high ejection fraction and little if any regurgitation.

On those echo tests, ask the doctor about your results for ejection fraction (or EF).

I learned a long time ago that to quote without shopping almost never works and to quote without all the facts is only moderately better, so when I am short on what I need, whether it is a copy of a surgical pathology report, a narrative summary of a stress test so I know your exact ejection fraction or a 5 year history of PSA results, nothing goes to the underwriter until you've supplied the supporting records.

The standard test for risk assessment in relation to life - threatening cardiac rhythm disturbances is currently the left ventricular ejection fraction, which represents a measure of the heart's function and measures the volume of the beat in relation to the overall volume of blood in the ventricle.

Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota — Themistoklis Katsimichas — Circulation Journal

Patients treated with processed autologous adipose - derived regenerative cells (ADRCs) injected into the heart muscle demonstrated symptomatic improvement and a trend towards lower rates of heart failure hospitalizations and angina, despite no improvement in left ventricle ejection fraction (LVEF) or ventricular volumes.

The control group did not experience the same increase in heart ejection fraction.

They would have cardiologist testing and imaging with ejection fraction of 60 % or greater and LVEF stability over 5 years.

The TOPCAT trial is the first randomized, double - blind trial to assess the effect of spironolactone on clinical outcomes in these patients with heart failure and preserved ejection fraction.

The rationale for using spironolactone - an inexpensive, generic, medication - stems from the pioneering research of Bertram Pitt, MD, University of Michigan School of Medicine, who showed the benefit of this class of drugs in patients with heart failure and reduced ejection fraction, and who also served as chair of the TOPCAT Steering Committee.

Ultrasound studies of the macaques» hearts showed that the ejection fraction, an indication of the hearts ability to pump blood, improved in some of the treated animals but not all.

A late - breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump function).

Of these, five patients had heart failure with low ejection fraction, when the heart muscle doesn't pump blood as well as it should, and one had heart failure with preserved ejection fraction, when the heart becomes stiff and can not relax or fill properly.

Iron deficiency is present in approximately 50 percent of patients with heart failure with reduced left ventricular ejection fraction (HFrEF; ejection fraction: a measure of how well the left ventricle of the heart pumps with each contraction) and is associated with reduced functional capacity, poorer quality of life, and increased mortality.

In patients with the implantable device, the heart got smaller, the left ventricular diastolic volume decreased significantly and the heart became stronger, with significant improvements in left ventricular ejection fraction.

Ejection fraction is measured by ultrasound and shows how well the heart is pumping.

Contrary to popular practice, a measure of the heart's pumping function known as «left ventricular ejection fraction» is not associated with the long - term outcomes of hospitalized heart failure patients, a UCLA - led study of Medicare patients has found.

Hospitalized heart failure patients in all age groups within the study and with all levels of ejection fraction had significantly lower rates of survival after five years and a higher risk of re-hospitalization than people in the United States without heart failure.

Although the primary endpoint was not met, a statistically significant 4 percent improvement was seen in a secondary endpoint, left ventricular ejection fraction — a measure of how much blood is being pumped out of the left ventricle — in patients whose STEMIs involved the front wall of the left ventricle (the heart's main pumping chamber), he said.

A new study by researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) found comparable long - term outcomes between congestive heart failure patients with preserved ejection fraction commonly known as «diastolic heart failure» and congestive heart failure with reduced ejection fraction also known as «systolic heart failure.»

The 10 - year Warfarin and Aspirin for Reduced Cardiac Ejection Fraction (WARCEF) trial is the largest randomized, double - blind comparison of aspirin and warfarin (also known by its brand name Coumadin) for heart failure, following 2,305 heart failure patients whose heart muscle pumps less oxygen - rich blood into the body, known as reduced ejection fraction, at 168 study sites in 11 countries on three continents.

All runners with decreased left ventricular ejection fraction (LVEF), a measure of cardiac pumping efficiency, after the race compared with baseline underwent a third MRI study after three months of rest to check whether it had reversed.

Mihai Gheorghiade, M.D., of the Northwestern University Feinberg School of Medicine, Chicago, and colleagues randomly assigned 456 patients with worsening chronic HF and reduced left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each beat) to receive placebo or 1 of 4 daily target doses of the medication vericiguat for 12 weeks.

• Subject has congestive heart failure New York Heart Association (NYHA) class 3 or 4, or subject with a history of congestive heart failure NYHA class 3 or 4 in the past, unless a screening echocardiogram performed within 3 months prior to study entry results in a left ventricular ejection fraction that is ≥ 45 %.

Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota

The team analyzed patient demographics such as age and ethnicity, in addition to the patient's ejection fraction (EF)-- the measurement of the percentage of blood leaving the heart each time it contracts — and whether the patient delivered twins, or had a cesarean delivery.

A large - scale metaanalysis on heart failure, using a huge individual patient dataset, found that diabetes was more frequent in women than men, including patients with both reduced and preserved ejection fraction (307).