Salicylic acid binding of mitochondrial alpha - ketoglutarate dehydrogenase E2 affects mitochondrial oxidative phosphorylation and
electron transport chain components and plays a role in basal defense against tobacco mosaic virus in tomato
One cause of this energy loss is a breakdown in the efficiency of the
electron transport chain, the main pathway through which we extract energy from food (and of which NAD + is an essential
component).23, 38 Disorders ranging from obesity and diabetes to bone loss have been associated with loss of this vital pathway.38, 39