Chance, along with Henry Lardy and later Ron Williams, worked out methods to separate mitochondria from cells and preserve their metabolic activity in vitro and invented the dual wavelength spectrophotometer to analyze mitochondrial
electron transport coupled to ATP synthesis.
Her current research focuses on understanding mass and
electron transport behavior at the atomic - scale, as well as
coupling materials physics with local lattice strain, bonding, and chemistry.
Dr. Rosso's current projects include the following: (1) characterizing the kinetics and mechanisms of elementary charge and ion
transport processes in redox transformation of iron oxide minerals, (2) predicting molecular - scale
electron transfer kinetics in microbially - mediated reduction of bioavailable iron in subsurface environments, (3) studying mechanisms of heterogeneous reduction of contaminant U (VI) and Tc (VII) by Fe (II)- bearing minerals, (4) simulation of
coupled charge and ion
transport in transition metal oxide electrodes for advanced materials applications, (5) probing mechanisms and kinetics of mineral transformation to metal carbonates for geological carbon sequestration, and (6) studying mechanisms of uptake and retention of uranium in sediments.