"Electrophysiological properties" refers to the characteristics or qualities related to the electrical activity of cells, tissues, or organs in the body. It involves measuring and analyzing the electrical signals and activities, such as nerve impulses or brain waves, to understand how they function and communicate within the body.
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Interestingly, Ascl1 alone already induces neuronal properties, but co-expression of the other factors strongly promotes a degree of differentiation, as you can see here in the acquisition of more
mature electrophysiological properties.
«Although responders and nonresponders both produce more electrical impulses and spontaneous activity, when we look at
the electrophysiological properties, the two groups are very different from each other.»
There are 21 different subtypes of GABAergic interneurons in the mammalian hippocampus, identified on their expression of different markers and
their electrophysiological properties.
«These hciNs [human chemical - induced neuronal cells] show similar morphology, gene - expression profiles, and
electrophysiological properties» to neurons derived from pluripotent stem cells, Zhao wrote in an email to The Scientist.