For example, we have built unique probes for real - time NMR studies of catalysts under operating conditions, single - particle laser ablation mass spectrometers for analysis of aerosol particles, and the nanospray
desorption electrospray ionization instrument for highly sensitive analysis of minute samples.
The most broadly useful methods for chemical and biochemical samples
use electrospray ionization - mass spectrometry (ESI - MS).
He adds that the microscope's electron beam is more powerful than natural settings, but the gelling effect could affect the lifetime of
electrospray thrusters in low - Earth and geosynchronous orbit.
The identities of the metabolites as lysine - SMCC - DM1 and lysine - PEG4Mal - DM1 were confirmed in a separate experiment
by electrospray mass spectrometry.
Among the lab's many discoveries are innovative uses
of electrospray ionization, which was developed by the late Yale Nobel laureate John Fenn.
To figure out the function of Gasp further, we attempted to identify proteins associated with Gasp by using liquid chromatography - based
electrospray tandem mass spectrometry (20).
Combining electrospun scaffolds
with electrosprayed hydrogels leads to three - dimensional cellularization of hybrid constructs.
Thomas Priest, a DOE Science Undergraduate Laboratory intern at PNNL, synthesized the gold clusters, creating a purple solution that
Johnson electrosprayed into a high - resolution mass spectrometer at EMSL.
That approach — known
as electrospray ionization — ionizes large molecules by dissolving them in a solvent and using an intense electric field to pull tiny charged droplets of solution from the end of a needle.
«We have demonstrated that we can
electrospray liquid precursors inside a high vacuum environment of an electron microscope and then use electrons to facilitate useful chemical transformations,» said Fedorov.
Reported here is the use of laser «cut and drop» sampling with a laser microdissection - liquid vortex
capture electrospray ionization tandem mass spectrometry (LMD - LVC / ESI - MS / MS) system for online and absolute quantitation of propranolol in mouse brain, kidney, and liver thin tissue sections of mice administered with the drug at a 7.5 mg / kg dose, intravenously.
Composites for delivery of therapeutics: Combining melt electrospun scaffolds with
loaded electrosprayed microparticles.
Johnson
then electrosprayed the solution into a unique custom - built mass spectrometer at EMSL that is specially designed for ion soft landing.
After electrospray ionization, selected ion fragments were detected and quantified in the API4000 triple - quadrupole tandem MSMS (Applied Biosystems / Sciex).
Zoltán Takáts, R. Graham Cooks, and colleagues at Purdue University in West Lafayette, Indiana, describe the new method, dubbed
desorption electrospray ionization (DESI), in the 15 October issue of Science.
Cells were then washed in medium, and metabolites were extracted with acetone and analyzed by reverse - phase high - performance liquid chromatography (HPLC) and
by electrospray mass spectrometry as described previously (19).
Moini, M., Jones, B. L., Rogers, R. M. & Jiang, L. Sodium trifluoroacetate as a tune / calibration compound for positive - and negative - ion
electrospray ionization mass spectrometry in the mass range of 100 — 4000 Da.
The new technique uses
an electrospray jet differently, to shoot ionized droplets of solvent at a sample.
The electrospray produces nanometer - scale charged droplets from a Taylor cone jet just 100 nanometers in diameter, which coalesce upon impingement and form a thin film of the precursor on the solid substrate.
The process involving liquid chromatography -
electrospray ionization - tandem mass spectrometry relies on a vital step called «charge derivatization» or using a permanently charged reagent to selectively trap the estrogens and isolate them from the lipids and proteins that could interfere with estrogen detection, Schug said.
The rocket, called
an electrospray thruster, is a drop of molten salt.
Two - dimensional polyacrylamide gel electrophoresis combined with chromatographic phosphoprotein pre-enrichment and
electrospray ionization mass spectrometry - based protein identification was used to reveal changes of phosphoproteins in cells exposed to cyclic stretching.
Liquid chromatography mass spectrometry (LCMS) was carried out using a Shimadzu LC - 20AD spectrometer at The Scripps Research Institute (La Jolla, CA, USA), and
electrospray ionization (ESI) mass analysis with a Thermo Scientific LTQ Orbitrap - XL spectrometer at the Salk Institute.
The electrospray turns the gold clusters in the liquid into ions in a gaseous stream.
This electrospray ionization kept similar molecules together so that scientists could capture and cool them in an ion trap.
The electrospray process turns the gold clusters in the liquid into positively charged ions in a gaseous stream.
Methods: The researchers began by generating a peptide, a portion of a protein, with two additional protons in
the electrospray ion source.
Thermo Scientific Q Exactive ™ Hybrid Quadrupole - Orbitrap ™ Mass Spectrometers coupled to Vanquish ™ and Dionex ™ UltiMate ™ ultra-high-pressure chromatography systems are capable of ionization using heated
electrospray (HESI), atmospheric pressure chemical ionization (APCI), and nano - flow electrospray (Nano - ESI).
His technique improved the speed and spatial resolution of DESI by adding a second capillary that turns molecules dissolved in the deposited liquid into ions by nano -
electrospray ionization.
Roach received his Ph.D. in 2009, shortly before joining PNNL to work in developing EMSL's desorption
electrospray ionization (DESI) mass spectrometry facility for application to study aerosol chemistry.
Phrases with «electrospray»