Sentences with phrase «electrospray ionization»

For example, we have built unique probes for real - time NMR studies of catalysts under operating conditions, single - particle laser ablation mass spectrometers for analysis of aerosol particles, and the nanospray desorption electrospray ionization instrument for highly sensitive analysis of minute samples.

The most broadly useful methods for chemical and biochemical samples use electrospray ionization - mass spectrometry (ESI - MS).

That approach — known as electrospray ionization — ionizes large molecules by dissolving them in a solvent and using an intense electric field to pull tiny charged droplets of solution from the end of a needle.

Among the lab's many discoveries are innovative uses of electrospray ionization, which was developed by the late Yale Nobel laureate John Fenn.

Reported here is the use of laser «cut and drop» sampling with a laser microdissection - liquid vortex capture electrospray ionization tandem mass spectrometry (LMD - LVC / ESI - MS / MS) system for online and absolute quantitation of propranolol in mouse brain, kidney, and liver thin tissue sections of mice administered with the drug at a 7.5 mg / kg dose, intravenously.

Moini, M., Jones, B. L., Rogers, R. M. & Jiang, L. Sodium trifluoroacetate as a tune / calibration compound for positive - and negative - ion electrospray ionization mass spectrometry in the mass range of 100 — 4000 Da.

After electrospray ionization, selected ion fragments were detected and quantified in the API4000 triple - quadrupole tandem MSMS (Applied Biosystems / Sciex).

Zoltán Takáts, R. Graham Cooks, and colleagues at Purdue University in West Lafayette, Indiana, describe the new method, dubbed desorption electrospray ionization (DESI), in the 15 October issue of Science.

Two - dimensional polyacrylamide gel electrophoresis combined with chromatographic phosphoprotein pre-enrichment and electrospray ionization mass spectrometry - based protein identification was used to reveal changes of phosphoproteins in cells exposed to cyclic stretching.

The process involving liquid chromatography - electrospray ionization - tandem mass spectrometry relies on a vital step called «charge derivatization» or using a permanently charged reagent to selectively trap the estrogens and isolate them from the lipids and proteins that could interfere with estrogen detection, Schug said.

Liquid chromatography mass spectrometry (LCMS) was carried out using a Shimadzu LC - 20AD spectrometer at The Scripps Research Institute (La Jolla, CA, USA), and electrospray ionization (ESI) mass analysis with a Thermo Scientific LTQ Orbitrap - XL spectrometer at the Salk Institute.

This electrospray ionization kept similar molecules together so that scientists could capture and cool them in an ion trap.

His technique improved the speed and spatial resolution of DESI by adding a second capillary that turns molecules dissolved in the deposited liquid into ions by nano - electrospray ionization.

Roach received his Ph.D. in 2009, shortly before joining PNNL to work in developing EMSL's desorption electrospray ionization (DESI) mass spectrometry facility for application to study aerosol chemistry.