Sentences with phrase «electrostatic interactions»
Electrostatic interactions refer to the force or attraction between electrically charged particles. They occur when positively charged particles are attracted to negatively charged particles or when similar charges repel each other. These interactions are based on the principle that opposite charges attract, while similar charges repel each other. Full definition
«The negative surface charge of nanoparticles enabled electrostatic interactions with therapeutics thus resulting in the slow release of therapeutics.»
sciencedaily.com
This suggests to the researchers that the first step in these reactions is dominated by weak electrostatic interactions between the reactants.
By applying DC and AC biases between the AFM probe and sample surface, DREEM can detect very weak electrostatic interaction differences when it scans over protein versus DNA regions.
This finding, along with a few other papers last year, emphasizes the importance of electrostatic interactions for protein stability, he says, and will enable protein chemists to create more stable protein - based drugs.
This suggested that the binding was largely based on electrostatic interactions, as observed in dengue virus.»
They identified other mechanisms that can produce hysteretic responses such as strong electrostatic interactions (similar to the force between a proton and electron).
On the basis of structural analysis of this protein, scientists demonstrated that specific mutations within the EGFR gene increase electrostatic interactions between the two dimer subunits of EGFR, stabilizing it in an «active» state, leading to cancer.
The bonds that prop proteins into their three - dimensional structure are the stuff of chemistry textbooks: electrostatic interactions from positively and negatively charged amino acids, hydrophobic entanglements of nonpolar amino acids that prefer similar company, and other more tenuous fasteners.
Contribution of electrostatic interactions, compactness and quaternary structure to protein thermostability: lessons from structural genomics of Thermotoga maritima.
Recent successful steps in this direction were for example identifying that hydrophobic mismatch and electrostatic interaction with the lipid PIP2 are driving the formation of active complexes of the SNARE protein synatxin - 1 in plasma membrane.
This is due to electrostatic interactions between the positive charges on the protein surface of photolyase and the negatively charged backbone of the DNA.
Charge separation on peptides creates permanent dipole moments that can be aligned with an electric field to provide optimal orientation of the molecules and the amount of peptide immobilised can also be tuned by the electrostatic interactions when the peptides have an overall charge.
By tinkering with the bonds that these dozen contribute to, the researchers determined that one electrostatic interaction and one hydrophobic interaction help the proteins handle hot water.
Their various adhesive, frictional and electrostatic interactions are computationally problematic, but the real challenge comes from sheer weight of numbers.